Cancer Weekly

Glottic Cancer - Multidimensional voice evaluation in pretreatment glottic carcinoma advised

Gynecologic Cancers - Long-term complications associated with Indiana pouch urinary diversion

Gynecology - Hormone antagonist stops experimental endometrial cancer

Gynecology - Recent studies add new data to gynecology research

HIV/AIDS Vaccine - Enrollment in protease inhibitor program for HIV/AIDS patients to begin in fall

HIV/AIDS Vaccine - U.S. NIH center places HIV vaccine production order for phase 2 trials

Head and Neck Cancer - Epstein-Barr virus latent membrane protein 1 triggers cancer invasion factors

Head and Neck Cancer - Glycobiology of head and neck squamous epithelia and carcinomas discussed

Helicobacter Pylori - Probiotics improves tolerance to Helicobacter pylori eradication therapy

Hematology - Reports add new data to hematology research

Hepatitis C - Hepatitis C treatment given orphan medicinal product designation in Europe

Hepatitis Vaccine - First sales of hepatitis A&B vaccine to Hunan Province, China CDC announced

Hepatocellular Carcinoma - Prior hepatitis B virus infection contributes to liver cancer formation

Herpesvirus - History of chickenpox and shingles recalled

Hormones - Clear cell variant of eccrine syringofibroadenoma described

Hormones - Hormone therapy for patients with hormone refractory prostate cancer discussed

Human Papillomavirus - Gene expression profile of cervical cells harboring HPV-16 reported

Human Papillomavirus - Survey finds women and doctors aren't talking about HPV

Human Papillomavirus Vaccine - Adenoviral vectors carrying IL-12 and E7 enhanced immunity to HPV-16

Human Papillomavirus Vaccine - HPV-16 vaccine elicits broad cytokine response in whole blood

Hypoxia - Hypoxia studied, protective role of vitamin C defined

Imaging - Company begins customer shipments of hand-held ultrasound imaging system

Imaging - Medical device company introduces newest member of computed tomography system

Inhibitory Factors - Leukemia inhibitory factor blocked early differentiation of skeletal muscle

Internuclear Ophthalmoplegia - Unusual causes of internuclear ophthalmoplegia tracked

Intracranial Meningioma - Intracranial meningiomas of childhood and adolescence studied

Ketoconazole - Long-term outcome for men with androgen-independent prostate cancer reviewed

Kidneys - MDCT urography of upper tract urothelial neoplasms evaluated

Laryngotracheal Resections - Laryngotracheoplastic resection for primary tumors of proximal airway described

Leiomyoma - Leiomyoma of the external auditory canal discussed

Leiomyosarcoma - Case of leiomyosarcoma of the renal vein reported

Leucovorin - Combinatory chemotherapy for metastatic colorectal cancer entered phase II trial

Leukemia - Leukemogenesis linked to covalent modifications of chromatin

Lipoma - Giant omental lipoma detected in an infant

Liposomes - Multidrug resistance modulator interacted with neutral and anionic liposomes

Liposomes - Novel mechanism of hybrid liposomes-induced apoptosis in human tumor cells found

Liver Abscess - Frequency and risk factors for liver abscess determined

Liver Cancer - Data advance knowledge in liver cancer research

Liver Transplantation - Guidelines recommended for surgical treatment of pediatric hepatoblastoma

Liver Transplantation - Urgent liver retransplantation extended survival

Liver Transplants - Hepatic transit time indicated therapeutic response to radiofrequency ablation

Liver Transplants - Interventional radiology advised for liver transplantation

Liver Transplants - Liver transplant outcomes for hepatocellular carcinoma reviewed

Liver Transplants - Recommendations for surgical treatment of hepatoblastoma outlined

Lung Cancer - Celecoxib chemoprevention trial has been reactivated

Lung Cancer - Clinical relevance of imaging proliferative activity in lung nodules evaluated

Lung Cancer - DNA scans reveal possible location of lung cancer genes

Lung Cancer - High-powered gene profiles provide clues to genes involved in lung cancer

Lung Cancer - Poor lung function increases cancer risk, especially in women

Lung Cancer - Researchers find lung cancer may begin in newly isolated lung stem cells

Lung Cancer - Researchers improve lung cancer survival rates

Lung Cancer - WHO launches project to minimize risks of radon

Lymphoma - Co-morbidity among elderly associated with decreased chemotherapy regimen

Lymphoma - Lymphoma-associated chromosomal abnormalities detected by FISH

Lymphoma - Management of non-Hodgkin lymphoma of the thyroid described

Lymphopenia - Adult thymus appears capable of regeneration until middle age

Marjolin Ulcer - Adequacy and efficacy of surgical excision alone in Marjolin's ulcer examined

Medical Devices - New supply agreement with St. Jude Medical for vascular closure device announced

Medullary Cancer - Calcitonin level increased in thyroid nodules without medullary carcinoma

Melanoma - Incidence of brain metastases in cutaneous head and neck melanoma seen rising

Melanoma - Incidence of brain metastases increased in cutaneous head and neck melanoma

Melanoma - Lovastatin induced apoptosis in human melanoma cell lines

Melanoma - Monster cells in malignant melanoma described

Melanoma - Primary site prognosis affected diagnosis of cutaneous malignant melanoma

Melanoma - Prognosis impacted by anatomical locations of cutaneous malignant melanoma

Meningiomas - Growth pattern changes of meningiomas analyzed

Meningitis - Neoplastic meningitis (NM) treatments described

Meningitis - Outcomes of patients with neoplastic meningitis revealed

Mergers & Acquisitions - Biotechnology company acquires intellectual property assets

Mergers & Acquisitions - Medical device company announces acquisition of Sensant Corp.

Mucinous Cancer - Clinicopathologic findings of mucinous carcinoma discussed

Multiple Myeloma - Azaspirane hinders cancer proliferation factors in the bone marrow environment

Multiple Sclerosis - Phase 3 2-year study of interferon beta-1b in early multiple sclerosis completed

Myelodysplastic Syndromes - U.S. FDA grants priority review for REVLIMID

Myeloma - Erk5 analyzed multifunctional role in multiple myeloma defined

Myeloma - International Staging System for multiple myeloma developed

Nephrogenic Diabetes Insipidus - Viagra shows potential vasopressin-independent cGMP signaling in NDI

Neuroblastic Tumors - Researcher looks at molecular pathology of neuroblastic tumors

Neuroblastoma - Fine tuning drug levels in neuroblastoma patients is effective, researchers show

Nocardiosis - Underlying diseases common in patients with nocardiosis

Omega 3 Fatty Acids - Report describes potential for omega-3 fatty acids to prevent CV conditions

Oncology - Cardiac hormones help decrease cancer cells

Oncology - Gene profiles support clinical management of large B-cell lymphoma

Oncology - Human papillomavirus genotype distribution

Oncology - Insulin receptor substrate 1 participates in breast cancer progression

Oncology - Raf signals drive VEGF in Kaposi sarcoma-associated herpesvirus-infected cells

Oncology - Researchers' data advance oncology research

Oncology - Transcription factor Spz1 sends tumor cell proliferation into overdrive

Oncology - Triterpenes found to induce apoptosis of cancer cells

Orofacial Tumors - Orofacial tumors in suburban Nigerian children and adolescents evaluated

Osteosarcoma - Clinicopathologic features of dedifferentiated parosteal osteosarcoma discussed

Osteosarcoma - Pharmacokinetics of cisplatin explained

Otorhinolaryngology - CT and MR imaging findings of selective neck dissection revealed

Ovarian Cancer - Absence of estrous cycle associated with paclitaxel hypersensitivity reaction

Ovarian Cancer - Ovarian cancer surgery quality indicators developed using unique Delphi approach

Ovarian Health - Lineage infidelity of epithelial ovarian cancers controlled by HOX genes

Pain Management - Companies announce antibody drug conjugate collaboration

Pancreatectomy - Laparoscopic spleen-preserving distal pancreatectomy detailed

Pancreatic Adenocarcinoma - Multidetector-row computed tomography eliminated role of diagnostic laparoscopy

Pancreatic Cancer - Accuracy of EUS diagnosis of vascular invasion in pancreatic cancer examined

Pancreatic Cancer - Efficacy of laparoscopic duodenopancreatectomy evaluated

Pancreatic Cancer - Keyhole limpet hemocyanin affected breast and pancreatic cancer

Pancreatic Cancer - LY293111 improved efficacy of gemcitabine therapy for pancreatic cancer

Pancreatic Cancer - Pancreatic tumors associated with pancreas divisum

Pancreatic Cancer - Researchers detail new studies and findings in the area of pancreatic cancer

Pancreatic Cancer - Therapeutics company initiates phase 2 trial of talabostat in pancreatic cancer

Pap Test - Physician recommendation improves likelihood of Pap testing

Patents - Biopharm company associated with U of Texas awarded additional Advexin patent

Patents - IMI announces three new skin sterol patents

Pediatric Oncology - S100A4 antisense oligodeoxynucleotide chokes neuroblastoma cell invasion

Personnel - Biopharmaceutical company forms 9-member head and neck cancer advisory board

Personnel - Biotechnology company builds senior management team

Personnel - Cancer-focused company announces three senior management promotions

Personnel - Cancer-focused company elects George Bickerstaff and Garry Willis to board

Personnel - David Sidransky, MD, named ImClone vice chairman

Personnel - Diane E. Paul, MS, RN, rejoins National Comprehensive Cancer Network

Personnel - Hematologist Pierre Laneuville, MD, named to cryogenics company advisory board

Personnel - Julia R. Brown appointed to biotechnology company's board of directors

Personnel - Paul J. Crowe, Keith Jacobsen named to board of surgical devices company

Pharmaceutical Research - Italian biotech experts visit Temple U to discuss genetic cancer research

Pharmaceutical Trends - First-line therapies significantly outspend second- and third-line drugs

Philanthropy - Gift from Ivey family, financial group is to accelerate brain disorder research

Premature Ovarian Failure - Model predicts induced sterility from radiotherapy to abdominal region

Product Licensing - GGTase Inhibitor compounds licensed to Duke University

Product Licensing - Genentech licenses antibody-drug conjugates directed against the PR1 antigen

Product Licensing - Helsinn and Angelini announce a license agreement for Aloxi in Portugal

Product Licensing - License agreement signed for intellectual property on Methylation Specific PCR

Product Licensing - License granted to cancer marker assays

Prostate Cancer - Biotech company published paper on phase II Onyvax-P trial

Prostate Cancer - Chromosomal changes characterized in Asian patients

Prostate Cancer - Definition of recurrence after radiation for prostate cancer revised

Prostate Cancer - Efficacy of unilateral nerve sparing in radical perineal prostatectomy evaluated

Prostate Cancer - Erectile dysfunction followed radical prostatectomy

Prostate Cancer - FAK required for bombesin-induced prostate cancer cell motility

Prostate Cancer - Intention to test for prostate cancer among men surveyed

Prostate Cancer - Limitations in use of serum prostate specific antigen levels uncovered

Prostate Cancer - Long-term outcome of radical prostatectomy reviewed

Prostate Cancer - Phase III enrollment complete in Provenge trial for early-stage prostate cancer

Prostate Cancer - Sca-1-enriched prostate-regenerating cells can initiate prostate tumorigenesis

Prostate Cancer - Statins should be tested as adjuvant therapy in prostate cancer trials

Prostatectomy - Radical perineal prostatectomy appraised from contemporary perspective

Proteomics - Endosialin has cell-specific expression in tumors

Pseudomonas Aeruginosa - Mab against P. aeruginosa protective against fatal pseudomonas sepsis

Pseudomonas Aeruginosa - Substance P regulates NK cell IFN-gamma production/resist to P. aeruginosa

Pulmonary Medicine - Limited resection trial conducted for pulmonary ground-glass opacity nodules

Radiation Medicine - Reticulocyte micronucleus assay detect radiation levels in affected individuals

Radiation Therapy - Hypopharyngeal carcinoma in Finland from 1990-1999 reviewed

Radical Cystectomy - Laparoscopic radical cystectomy performed in females

Rectal Cancer - Fruit and vegetable consumption did not decrease colorectal cancer in Japan

Rectal Cancer - Laparoscopic excision compared to open total mesorectal excision

Renal Cancer - Gastrin releasing peptide receptor may affect tumor microcirculation

Renal Cell Cancer - Primary tumor classification for renal cell carcinoma updated

Risk Assessment - Mode of action aided risk assessment

Saccharomyces Cerevisiae -  Saccharomyces cerevisiae fungemia is an emerging infectious disease

Smoking - Association of tooth loss with disease risk was not confounded by smoking

Soft Tissue Sarcoma - Radiation morbidity compared between preoperative and postoperative radiotherapy

Squamous Cell Cancer - Conjunctival squamous cell carcinoma with perineural invasion resulted in death

Stem Cell Blood Banking - Umbilical cord blood banks for transplantation differ in levels of quality

Stem Cell Research - Mesenchymal stem cells remain of host origin long after APBSCT or BMT

Stem Cell Research - PI-MECs are cellular targets for pregnancy-enhanced mammary tumorigenesis

Stem Cell Transplantation - Clinical sequelae following microbially-contaminated SC infusions are rare

Stem Cell Transplantation - Mismatched-related cells are a viable therapy for patients with acute leukemia

Stem Cell Transplantation - T-cell chimerism molecular monitoring early after SCT predicts GVHD grades II-IV

Stress - Hydrogen peroxide stress resistance studied, role of nitric oxide clarified

Surgical Residency - Recent reduction in working hours impacted surgical resident cancer education

T Cells - Transcription factor analyzed, effect of expression on T cells defined

Testicular Cancer - Researchers find first gene for inherited testicular cancer in mice

Therapeutic Vaccines - Poor T-cell responsiveness limits current development approaches

Thrombosis - Resection of jugular vein necessitated by radical neck dissection

Thyroid Cancer - Combined suicide/cytokine gene therapy kills thyroid carcinoma cells

Thyroid Cancer - Recognition of thyroid carcinoma in rapid-consultation specimens improved

Thyroid Gland - Management of recurrent laryngeal nerve paralysis after thyroid surgery assessed

Thyroid Gland - Response to treatment in children with differentiated thyroid carcinoma assessed

Transcriptional Repression - Transcriptional repression of p21 studied

Transitional Cell Cancer - Endoscopic treatment of upper tract transitional cell carcinoma evaluated

Tumor Distribution - Different pneumoperitoneal pressures influenced tumor cell distribution in rats

Urothelial Cancer - Prognostics factors for recurrence after organ-preserving tumor resection found

Uterine Papillary Serous Carcinoma - Pap smear useful in cytomorphological tumor analysis

Vaccinia Virus - Cancer drug can slow poxvirus in mice

Vector Development - Reports advance knowledge in vector development research

Wound Closure - Carbon dioxide pneumoperitoneum technique used for wound closure in rat model