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Head and Neck Cancer

Genetic profiles classify oral squamous cell carcinomas

Published in Cancer Weekly, July 26th, 2005

Genetic profiles classify oral squamous cell carcinomas.

In a recent study, researchers in Spain conducted research "to study the gene expression profile of oral squamous cell carcinomas. Gene expression profile was investigated in oral squamous cell carcinomas in 5 patients using the Atlas Glass Human 3.8 I Microarray (which detects cDNA obtained from cellular total RNA)."

"Data were normalized by the LOWESS method. Statistical significances of deviations from a 1:1 ratio were evaluated by t tests, with p<0.05. Of the 3757 genes analyzed, 322 (8.6%) were significantly overexpressed in tumoral tissue with respect to normal tissue, while 104 (2.8%)...

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