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Human Papillomavirus

HPV 63 targets keratinocytes in or around eccrine ducts in plantar skin

Published in Cancer Weekly, July 26th, 2005

Human papillomavirus 63 targets keratinocytes in or around the eccrine ducts in the plantar skin.

According to a study from Japan, "The primary target cell of human papillomaviruses (HPVs) is an unsettled issue. Recent studies have suggested that the hair follicle is an important candidate as the reservoir of certain HPV types. However, little is known about the cells which serve as the target or the reservoir of HPVs in nonhairy palmoplantar skin."

"To investigate whether the eccrine sweat gland," wrote K. Egawa and colleagues at Kumamoto University, "the only skin appendage in nonhairy palmoplantar skin, also serves as the target or the reservoir...

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