Published in Cancer Weekly, July 26th, 2005
Gene amplification is a process that often happens in cancer cells when the normal DNA replication process is altered, causing many copies of the gene to be produced instead of a single copy of a region of a chromosome.
The researchers found that the MITF (microphthalmia-associated transcription factor) master regulator is the target of gene amplification in melanoma. MITF amplification also was more prevalent in metastatic disease and was correlated with decreased overall patient...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.