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Apoptosis

Environmental UV-A and UV-B threshold doses for treating fibroblasts estimated

Published in Cancer Weekly, August 9th, 2005

Scientists estimated the environmental UV-A and UV-B threshold doses needed for inducing apoptosis in human fibroblasts.

"Apoptosis involves a highly organized and programmed series of events aimed at maintaining genomic stability by eliminating defective host cells. The purpose of this study was to determine the threshold doses and environmental UV-A and UV-B exposure times necessary to produce apoptosis and necrosis in the normal cells of a human fibroblast cell line," researchers in the United States reported.

"Environmental UV-A and UV-B doses were measured over a 6 year period with a four-channel UV radiometer. The fibroblasts were irradiated...

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