Cancer Therapy
Antitumor drug NK109 interacted with PNxxxxP
Published in Cancer Weekly, August 16th, 2005
"The synthetic compound NK109 shows antitumor effects against a number of human cancer cell lines. The mechanism of action is thought to involve the inhibition of DNA topoisomerase II," scientists in Japan reported.
"However, NK109 also exhibits potent antitumor activities against doxorubicin-, cisplatin- and etoposide-resistant human cell lines. This paper describes target validation of NK109 using biotinylated NK109 and a T7 phage library screening procedure," explained K. Morohashi and colleagues, Genome & Drug Research Center.
"Phage particles displaying...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
Source: Cancer Weekly (2005-08-16)
More Articles from Cancer Weekly
- Cognitive Science
Cancer listed as risk factor for long-term cognitive deficits and dementia - Coping Strategies
Social support and hopelessness examined in Turkish cancer patients - Drug Development
Continuous toxicity monitoring advised in oncologic phase II trials - Epidemiology
Correctable sources of disparities in cancer among minority elders identified - Prostate Cancer
Pilot study aimed to determine support during pre-treatment of prostate cancer - Actin
SPECs examined, role in synapse F-actin accumulation clarified - More from this issue of Cancer Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
