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Cancer Treatments

Changes of thymidine kinase helped monitor effects of chemotherapy

Published in Cancer Weekly, August 23rd, 2005

Researchers suggested that changes of thymidine kinase (TK) could help monitor the effects of adjuvant and palliative chemotherapy.

"Thymidine kinase is involved in nucleic acid synthesis and is, therefore, considered to be an important proliferation tumor marker. For this reason, we monitored this marker in the course of colorectal cancer chemotherapy. We examined TK levels in 30 patients with colorectal cancer who underwent adjuvant or palliative chemotherapy (CHT schemes)," scientists writing in the journal Anticancer Research reported.

"The condition for being included in the study was a minimum of 3 cycles of chemotherapy. TK was always...

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