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Thyroid Gland

MIB-1 compared with topoisomerase II-alpha immunostaining

Published in Cancer Weekly, August 23rd, 2005

Researchers compared the proliferative markers, molecular immunology borstel (MIB)-1 and topoisomerase II-alpha immunostaining, against one another.

"The differential diagnosis of well-differentiated tumors of follicular cell origin remains a most problematic task in thyroid pathology. Therefore, various diagnostic/prognostic thyroid markers are currents being studied," investigators in Czech Republic reported.

"The aim of our study was to evaluate the proliferative MIB-1 and topoisomerase II-alpha markers in both oncocytic and non-oncocytic epithelial thyroid tumors. Proliferative activity was analyzed by means of immunohistochemistry in 215 thyroid...

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