Breast Cancer

Low levels of 25(OH)D and polymorphisms in VDR increased risk of breast cancer

Published in Cancer Weekly, August 23rd, 2005

Low levels of 25-hydroxy vitamin D [25(OH)D] and polymorphisms in the vitamin D receptor gene (VDR) increased the risk of breast cancer.

"Low levels of 25(OH)D and polymorphisms in VDR have been found separately to increase risk of breast cancer. The aim of this study was to determine whether low 25(OH)D levels, alone and in combination with BsmI VDR genotype, increased breast cancer risk in a United Kingdom (UK) Caucasian population," investigators in England reported.

"Breast cancer patients (n=179) and control women (n=179) were recruited and 25(OH)D levels measured by enzyme-linked immunosorbent assay (ELISA). VDR genotype was determined by...

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Source: Cancer Weekly (2005-08-23)

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