Leukemia
Novel induction therapy for refractory acute myeloid leukemia reported
Published in Cancer Weekly, September 27th, 2005
"Purine nucleoside analogues, cladribine (2-chlorodeoxyadenosine, 2-CdA) and fludarabine (FAMP) are active agents in AMLs. Synergistic interaction between FAMP or 2-CdA with cytarabine (cytosine arabinoside, Ara-C) has been demonstrated in preclinical and clinical studies," researchers in Poland reported.
"The current multicenter phase II study was initiated to evaluate the efficacy and toxicity of induction treatment consisting of 2-CdA (5 mg/m2), Ara-C (2 g/m2), mitoxantrone (MIT, 10 mg/m2) and granulocyte...
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Source: Cancer Weekly (2005-09-27)
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