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Breast Cancer

Tamoxifen compared with anastrozole for treatment of early breast cancer

Published in Cancer Weekly, September 27th, 2005

Tamoxifen was recently compared to anastrozole for treatment of early breast cancer.

Tamoxifen, which is actually the gold standard adjuvant treatment in estrogen receptor-positive early breast cancer, is associated with an increased risk of endometrial cancer and other life-threatening events," according to recent research from Italy. "Moreover, many women relapse during or after tamoxifen therapy because of the development of resistance."

"Therefore new approaches are required," stated F. Boccardo and colleagues. They "conducted a prospective randomized trial to test the efficacy of switching postmenopausal patients who were already receiving...

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