Breast Cancer Vaccines

Researchers' data advance breast cancer vaccines research

Published in Cancer Weekly, September 27th, 2005

Data on breast cancer vaccines are outlined in reports from Sweden, Italy and the United States.

Study 1: A single vaccination with polyomavirus VP1/VP2Her2 virus-like particles prevents outgrowth of HER-2/neu-expressing tumors.

According to a study from Sweden and Italy, "Murine polyomavirus (MPyV) VP1 virus-like particles (VLPs), containing a fusion protein between MPyV VP2 and the extracellular and transmembrane domain of HER-2/neu (Her2), Her2_1-683 PyVLPs, were tested for their ability to vaccinate against Her2-expressing tumors in two different in vivo models. Protection was assessed both against a lethal challenge with a BALB/c...

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Source: Cancer Weekly (2005-09-27)

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