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Hepatitis B virus subtypes in African strains indicate stable variants

Published in Cancer Weekly, October 4th, 2005

Hepatitis B virus subtypes in African strains indicate stable variants.

"Hepatitis B virus (HBV) is a major cause worldwide of liver disease, including hepatocellular carcinoma. There are eight known genotypes (A-H), of which genotype A has been divided into two subtypes: A2, prevalent in Europe, and A1, which is prevalent in sub-Saharan Africa, but also occurs in southern Asia," scientists in Sweden report.

"In this study, which includes 14 new complete genomes of non-European genotype A HBV, it was found that West African strains seem to constitute a new subgroup, A3. The high degree of genetic diversity within Africa indicates that genotype A...

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