Virology

Findings in virology provide new insights

Published in Cancer Weekly, October 4th, 2005

Reports from the United States and Germany highlight recent research on virology.

Study 1: Transposon-based systems seek insertion sites to improve viral gene delivery.

According to a study from the United States, "therapeutic gene delivery from an oncolytic adenovirus (Ad) is one approach to enhancing the potency of Ad-based virotherapies for cancer. To identify therapeutic transgene insertion sites compatible with the replicating virus, a methodology that broadly scans the viral genome is needed."

"To address this we modified a transposon (Tn7)-based in vitro transposition system to take advantage of its nonprejudiced scanning...

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Source: Cancer Weekly (2005-10-04)

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