Oncology
53BP1 is required for RPA2 hyperphosphorylation following DNA damage
Published in Cancer Weekly, October 11th, 2005
According to recent research from South Korea, "P53-binding protein 1 (53BP1) acts as an 'adaptor/mediator' for transducing DNA damage signals, especially following detection of DNA double-strand breaks. In an effort to broaden our understanding of the protein network surrounding 53BP1, we isolated possible 53BP1 binding partners by co-immunoprecipitation, and identified them via tandem mass spectrometric analysis."
"The 53BP1-associated proteins included RPA1 and RPA2, two components of the replication...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
Source: Cancer Weekly (2005-10-11)
More Articles from Cancer Weekly
- Breast Cancer
Molecular tumor subtype influences preoperative chemotherapy efficacy - Cancer Therapy
Cone-beam-CT guided radiation therapy used as model for on-line application - Cancer Therapy
Intensity-modulated radiation therapy used in head and neck cancers - Lung Cancer
Asian ethnicity and adenocarcinoma histology predicted response to gefitinib - Prostate Cancer
Active Stat5 predicts early recurrence - Acute Lymphoblastic Leukemia
Rapamycin stimulates apoptosis of childhood acute lymphoblastic leukemia cells - More from this issue of Cancer Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
