Published in Cancer Weekly, October 11th, 2005
"Rare, highly penetrant germ line mutations in BRCA1 strongly predispose women to a familial form of breast and ovarian cancer," scientists in the United States report. "Whether common variants (either coding or noncoding) at this locus contribute to the more common form of the disease is not yet known."
M. L. Freedman and colleagues "tested common variation across the BRCA1 locus in African American, Native Hawaiian, Japanese, Latino, and White women in the Multiethnic Cohort Study. Specifically, 28 single nucleotide polymorphisms (SNPs) spanning...
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