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Diagnostics

Physical basics and clinical applications of first-pass DSC MRI evaluated

Published in Cancer Weekly, October 18th, 2005

Researchers discussed the physical basics and clinical applications of first-pass dynamic susceptibility-weighted contrast-enhanced (DSC) MRI.

"Perfusion imaging in the central nervous system (CNS) is mostly performed using the first-pass DSC MRI. The first-pass of a contrast bolus in brain tissue is monitored by a series of T2*-weighted MR images," scientists writing in the journal Radiologe reported.

"The susceptibility effect of the paramagnetic contrast agent leads to a signal loss that can be converted, using the principles of the indicator dilution theory, into an increase of the contrast agent concentration. From these data, parameter...

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