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Breast Cancer

Use of blue dye for sentinel lymph node biopsy should be minimized

Published in Cancer Weekly, October 18th, 2005

Although blue dye for sentinel lymph node biopsy in breast cancer provided marginal benefits, its use should be minimized due to allergic reaction.

"The use of isosulfan blue dye in sentinel node biopsy for breast cancer has been questioned because of its risk of allergic reaction. We hypothesized that blue dye could be safely omitted in the subgroup of patients who have evidence of successful sentinel node localization by lymphoscintigraphy. A retrospective review of patients with breast cancer and sentinel node biopsy was conducted," scientists in the United States reported.

"Information was collected on lymphoscintigraphy results, use of blue dye,...

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