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Brain Cancer

Anaplastic brainstem oligodendroglioma associated with allelic loss

Published in Cancer Weekly, October 18th, 2005

Researchers associated anaplastic brainstem oligodendroglioma with allelic loss in the tumor suppressor candidate region D19S246 of chromosome 19.

According to a study from Germany, "We report the case of a 9-year-old boy clinically presenting with severe headache, vomiting, head retroflexion, nystagmus, and ataxia. Magnetic resonance imaging showed brainstem enlargement leading to the diagnosis of an inflammatory process."

"In addition, the clinical picture, a monocytic cerebrospinal fluid pleocytosis with elevated protein and lactate and serum IgM antibodies to Mycoplasma pneumoniae favored this diagnosis. Subsequently, corticosteroid...

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