Lung Cancer

Troxacitabine used to treat patients with advanced non-small-cell lung cancer

Published in Cancer Weekly, October 18th, 2005

A phase II study of troxacitabine (BCH-4556) was conducted in patients with advanced non-small-cell lung cancer (NSCLC).

According to recent research published in the journal Lung, "Troxacitabine, a promising new L-nucleoside, inhibits DNA polymerase and leads to complete DNA chain termination. The National Cancer Institute of Canada Clinical Trials Group (NCIC-CTG) conducted a phase II study to assess the efficacy and toxicity of troxacitabine in untreated patients with advanced NSCLC."

"Previously untreated patients were eligible if they had inoperable stage IIIB or IV NSCLC, ECOG PS {{<=}}2, adequate hematology and biochemistry, and at...

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Source: Cancer Weekly (2005-10-18)

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