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Cancer Risk Factors

Hepatitis C virus may account for some cases of splenic large B-cell lymphoma

Published in Cancer Weekly, October 25th, 2005

Hepatitis C virus (HCV) may account for some cases of splenic large B-cell lymphoma.

"Hepatitis virus infection, especially type C, has been suggested to be one of the important pathogenetic factors for low- and high-grade B-cell lymphoma, including splenic marginal zone lymphoma (SMZL), in southern Europe," according to investigators in Japan.

"Here, we analyzed the incidences of HCV and hepatitis B virus (HBV) infections, and the clinicopathologic features in 29 cases of splenic diffuse large B-cell lymphoma (DLBCL), 10 SMZL, 3 splenic mantle cell lymphoma, 1 hairy cell leukemia, 13 B-chronic lymphocytic leukemia, and 12 hepatosplenic T-cell and...

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