Breast Cancer
Estrogen receptor-alpha regulates SOCS-3 expression in breast cancer cells
Published in Cancer Weekly, November 1st, 2005
According to a recent report from Sweden, "The suppressor of cytokine signaling (SOCS) protein family negatively regulates cytokine action. In this study, we investigated the effects of estrogen (E2) on SOCS-3 expression in T47D and MCF-7 human breast cancer cells."
"Real-time PCR analysis of E2-treated T47D cells revealed a ligand and time-dependent increase in of SOCS-3 mRNA levels. Cloning of a 1.7 kb fragment of the human SOCS-3 5' flanking sequence, and subsequent analysis of potential transcription factor-binding sites identified an incomplete ERE motif located -1493 to...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
Source: Cancer Weekly (2005-11-01)
More Articles from Cancer Weekly
- Anticancer Drugs
TrxR inhibition contributes to cytotoxicity of anticancer compounds - Cancer Risk Factors
Susceptibility to carcinogens increased with early-life exposure - Cancer Therapy
Adjuvant chemotherapy proposed for stage II colorectal cancer - Leukemia
AMN107 performed better as inhibitor of Ph-positive leukemia than imatinib - Paclitaxel
Combination therapy had significant effect on reduction of prostate tumor volume - Alternative Surgery
Median sternotomy proposed as alternate approach to extrapleural pneumonectomy - More from this issue of Cancer Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
