Adverse Drug Reaction
Case study suggests hydroxyurea therapy may be implicated in neuroendocrine carcinoma
Published in Cancer Weekly, November 8th, 2005
According to recent research from France, "Many cutaneous side-effects of long-term use of hydroxyurea therapy are well-known. We report the first case, to our knowledge, of a neuroendocrine carcinoma located on the finger associated with other cutaneous changes due to this drug."
"Our patient received HU for 2 years for a thrombocytemia. This treatment was stopped because of a dermatomyositis-like eruption. Two years later, she developed multiple keratotic lesions, and 8 years later, a Merkel cell carcinoma on the third left finger with metastasic...
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Source: Cancer Weekly (2005-11-08)
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