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Cancer Therapy

Mechanism for chemopreventive therapy may be similar for pre- and postmenopausal women

Published in Cancer Weekly, November 8th, 2005

Researchers determined that the post-resection mechanism for chemopreventive metastases is similar, but of different magnitude, in both pre-and postmenopausal women.

"The aim of" recent research from Italy "was to better understand human breast cancer biology by studying how the timing of metastasis following primary resection is affected by adjuvant CMF (cyclophoshamide, methotrexate, 5-fluorouracil) chemotherapy."

R. Demicheli and colleagues described their study: "Discrete hazards of recurrence and recurrence risk reductions for treated patients relative to controls were analyzed for all patients enrolled in two separate randomized clinical trials...

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