Published in Cancer Weekly, November 15th, 2005
"Extravasation has been described as a rate-limiting step in the process of hematogeneous metastasis formation. Thereby, transendothelial migration of tumor cells consists of a complex series of events involving multiple cell-cell and cell-matrix interactions," investigators in Germany reported.
"3D-extravasation assays are valuable tools for the identification of genes, which are the key players at switchboards of the intracellular signaling pathways," explained B. Brandt and colleagues, University of Witten Herdecke.
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