Cancer Weekly

Cancer Risk Factors - Cell phone use not related to risk of acoustic neuroma

Cancer Risk Factors - Maternal history of miscarriage associated with increased risk of childhood AML

Genetics & Genomics - Atypical protein kinase C iota identified as oncogene in lung cancer

Acute Myeloid Leukemia - Phase II study to evaluate Xanafide in combination with ara-C for secondary AML

Angiology - The JAK2/STAT5 pathway maintains neovascular growth during oxygen deprivation

Apoptosis - Accumulation of p53 sensitizes human cells to tumor necrosis factor alpha-induced apoptosis

Apoptosis - Activator protein 2 alpha status determines chemosensitivity of cancer cells

Apoptosis - Apoptotic specific regulator of p53 discussed

Apoptosis - Bile acids affected cell growth and death in human colonic adenocarcinoma cells

Bladder Cancer - Research in bladder cancer provides new insights

Apoptosis - Eicosapentenoic acid induced apoptosis in human pancreatic cancer cells

Apoptosis - Fluorescence-enhanced flow cytometry developed for screening of apoptotic statins

Apoptosis - Full-length p73 alpha repressed drug-induced apoptosis in lung carcinoma cells

Apoptosis - Hyperthermia induced apoptosis in ras-transformed lung cells

Apoptosis - Immunosuppression by morphine-induced lymphocyte apoptosis did not occur

Apoptosis - Paclitaxel induces apoptosis via caspase-3 activation in human osteogenic sarcoma cells

Breast Cancer - Findings describe new data in breast cancer research

Bioterrorism - U.S. grants $20 million for developing compounds to treat radiation damage

Bladder Cancer - Findings in bladder cancer provide new insights

Brachytherapy - Age found to be an indicator of sexual function after brachytherapy

Brain Cancer - Chest CT and brain MRI provide optimal evaluation of patients with newly detected brain mass

Brain Cancer Therapy - Pemetrexed has limited distribution to brain

Breast Cancer - New findings in the area of breast cancer described

Breast Cancer - CAD company introduces program for digital mammography screening

Breast Cancer - Clues may help early detection of breast cancer

Breast Cancer - Couple-focused group intervention helps women coping with breast cancer

Breast Cancer - Deregulation of X-linked genes may promote mammary gland tumorigenesis

Breast Cancer - Findings advance knowledge in breast cancer research

Breast Cancer - New research in the area of breast cancer detailed

Breast Cancer - HPLC method detects quercetin, kaempferol and isorhamnetin in human breast cancer cells

Breast Cancer - Herceptin plus chemotherapy shown to reduce risk of breast cancer recurrence

Breast Cancer - IHC is better predictor of Her2 gene amplification by FISH than HercepTest

Breast Cancer - Incidence of male breast cancer in California, 1988-2000, discussed

Breast Cancer - Insertion technique doesn't affect performance of MammoSite brachytherapy catheter

Breast Cancer - IoGen clinical trial to focus on proliferative benign breast disease

Breast Cancer - Researchers detail new studies and findings in the area of breast cancer

Breast Cancer - MRI detects increased vessel growth in breasts containing cancer

Breast Cancer - Phase II trial of combination therapy for advanced breast cancer underway

Breast Cancer - Researchers' data advance breast cancer research

Breast Cancer - Targeted ultrasound proven effective in correlating MRI abnormalities

Breast Cancer - U.S. radiation oncologists are warming up to hyperthermia

Breast Cancer Risk Factors - Study found cystic disease is not significant risk factor for breast cancer

Breast Cancer Risk Factors - Study shows obesity reduces risk of breast cancer in premenopausal women

Breast Cancer Treatment - Chemotherapy-related bone loss is attenuated by tamoxifen treatment

Business & Finance - Genomics company reports first quarter net loss of $16.7 million

Cancer Therapy - Reports add new data to cancer therapy research

Cancer Clinical Trials - Recommended phase II dose for T900607 determined

Cancer Diagnosis - Gastrointestinal stromal tumors should be considered as new lesions

Cancer Fatigue - Fatigue in cancer patients not related to changes in oxyhemoglobin dissociation

Cancer Impact - Impact of cancer on labor market analyzed

Cancer Management - Conference explores issues in cancer patient management, including depression and gender bias

Cancer Pain Management - Age and tumor type significantly influence transdermal fentanyl absorption

Cancer Therapy - Researchers report details of new studies and findings in the area of cancer therapy

Cancer Prevention - Long-term interferon therapy for chronic hepatitis C prevents liver cancer

Cancer Prevention - New strides are being made in cancer chemoprevention

Cancer Prevention - Researchers provide details of new studies and findings in the area of cancer prevention

Cancer Research - New European legislation impacts both cancer trials and drug approval

Cancer Research - Patient enrollment begins in phase I trial of Tarvacin anticancer

Cancer Research - Resource inadequacies hamper cancer surveillance research

Cancer Therapy - Studies advance knowledge in cancer therapy research

Cancer Research - UVA and UVB induce melanoma-associated growth factors in fibroblasts

Cancer Risk Factors - Bladder cancer risk elevated in painters

Cancer Risk Factors - CAV-I haplotype associated with familial aggressive prostate cancer

Cancer Risk Factors - Meat consumption correlated to colon and rectal cancers

Cancer Risk Factors - Polymorphism in 5' flanking region of SMYD3 linked to risk of human cancers

Cancer Risk Factors - Polymorphism in 5'-flanking region of CYP2E1 gene linked to lung cancer risk

Cancer Vaccines - Recent findings in cancer vaccines provide new insights

Cancer Therapy - Administering dendritic cells in cancer nodules in hepatocellular carcinoma appears safe

Cancer Therapy - Anticancer drug gets fast track for elderly with acute myelogenous leukemia

Cancer Therapy - Anticoagulant treatment improved survival in cancer patients

Cancer Therapy - Antitumor activity of 3-chlorodeoxylapachol demonstrated

Cancer Therapy - Antitumor agent JNJ-7706621 inhibits cyclin-dependent kinases and aurora kinases

Cancer Therapy - Central nervous system chemoprophylaxis in non-Hodgkin lymphoma requires standardization

Cancer Vaccines - Research add new data to cancer vaccines body of knowledge

Cancer Therapy - Chemophase phase I trial initiated for superficial bladder cancer

Cancer Therapy - CoFactor, in combination with 5-FU and oxaliplatin, may be effective against colorectal cancer

Cancer Therapy - Cost of epoetin alfa and darbepoetin alfa treatment in Sweden evaluated

Cancer Therapy - Emesis adversely affected clinical and economic outcomes of cancer therapy

Cancer Therapy - Gemcitabine plus Apo2L/TRAIL resulted in a greater antitumor effect

Cancer Therapy - IRFAPA recommended over PRFA therapy if patients' conditions permit laparotomy

Cancer Vaccines - Research in cancer vaccines provides new insights

Cancer Therapy - Interleukin-21 enhances tumor rejection through a NKG2D-dependent mechanism

Cancer Therapy - Intraperitoneal hyperthermic chemotherapy used for peritoneal surface malignancy

Cancer Therapy - Modification of treatment protocols improved outcome of childhood leukemia

Cancer Therapy - New sensors developed to help improve cancer radiation treatment

Cancer Therapy - New studies highlight promising potential of cancer immunotherapy

Cancer Therapy - Nonsteroidal inhibitors of 17beta-HSD317 were identified for prostate cancer treatment

Cancer Vaccines - Researchers' work adds to cancer vaccines body of knowledge

Cancer Therapy - Paclitaxel was well tolerated but showed limited efficacy in bronchioloalveolar carcinoma

Cancer Therapy - Pennsylvania researchers study the use of ultrasound for cancer treatment

Cancer Therapy - Photodynamic therapy with mTHPBC is safe and feasible treatment for liver metastases

Cancer Therapy - Porphyrin superoxide dismutase mimetic enhanced tumor radio-responsiveness

Cancer Therapy - Progressive muscle relaxation training reduced chemotherapy side effects

Cancer Therapy - Quality of life considerations impact choice of cancer treatment

Cancer Vaccines - Studies describe new findings in cancer vaccines research

Cancer Therapy - Recent studies add new data to cancer therapy research

Cancer Therapy - Second-line chemotherapy showed modest activity in patients with hormone-refractory prostate cancer

Cancer Therapy - Sentinel node biopsy recommended before neoadjuvant chemotherapy

Cervical Cancer - Researchers' findings advance cervical cancer research

Cancer Therapy - Tarceva now available in Europe to tackle growing lung cancer epidemic

Cancer Therapy - Tumor types selected for phase II trials of Coramsine

Cancer Vaccine - Bacterial mimic under study as cancer vaccine may also help protect tumors

Cancer Vaccines - Findings in cancer vaccines provide new insights

Hematology - Researchers' findings advance hematology research

Carcinogenesis - Interleukin-1 receptor antagonist gene polymorphism linked to colorectal cancer

Cervical Cancer - Cytokine pattern in women with CIN III lesions shifts during carcinogenesis

Cervical Cancer - Reports describe recent advances in cervical cancer research

Hepatocellular Carcinoma - Recent findings in hepatocellular carcinoma described

Cervical Cancer - Similar outcome seen in pregnant and non-pregnant women treated with neo-adjuvant chemotherapy

Chemotherapy - 5-aza-2'-deoxycytidine sensitizes hepatoma and pancreatic cancer cell lines

Chemotherapy - Cardiac toxicity in breast cancer treated with doxorubicin and paclitaxel

Chemotherapy - Chemotherapy induced toxic myelopathy

Chemotherapy - Cisplatin plus epirubicin deemed effective regimen in malignant mesothelioma

Leukemia - Studies add new findings to leukemia body of knowledge

Chemotherapy - Delayed onset bleomycin-induced pneumonitis observed

Chemotherapy - Dose-dense chemotherapy may be superior to CHOP for primary mediastinal large B-cell lymphoma

Chemotherapy - Dosimetry of docetaxel plus estramustine performed for prostate cancer

Chemotherapy - Early efficacy of epoetin alfa superior to darbepoetin alfa

Chemotherapy - Etoposide, leucovorin, and 5-fluorouracil used to treat resected gastric cancer

Chemotherapy - Intracavitary chemotherapy used to treat recurrent glioblastoma

Leukemia - Studies describe new findings in leukemia research

Chemotherapy - Razoxane was combined with radiotherapy for treatment of melanoma brain metastases

Choroidal Melanoma - Local tumor control achieved after Ru-106 brachytherapy of choroidal melanoma

Clinical Trials - Cost of insurance policies for investigator-initiated cancer clinical trials in Italy discussed

Clinical Trials - Dolastatin-10 ineffective in phase II clinical trials

Clinical Trials - Phase I dose-escalation trials in healthy volunteers overviewed

Collaborations - Agreement signed with M.D. Anderson Cancer Center for emerging recurrent cervical cancer prognostic

Oncology - Findings in oncology provide new insights

Collaborations - Alliance to focus on production of a novel protein targeting cancer

Collaborations - Development, commercialization agreement targets pulmonary hypertension

Collaborations - NAT maker to collaborate with Molecular Profiling Institute to bolster oncology strategy

Collaborations - Strategic agreement extended to discover blood diagnostics for cancer detection

Colon Cancer - Aberrant cytochrome c oxidase subunit I expression is biomarker for increased colon cancer risk

Colon Cancer - Colorectal cancer treatment is not consistent between races and ethnicities

Oncology - New data illuminates research in oncology

Colon Cancer - Findings in colon cancer provide new insights

Colon Cancer - Scientists develop colon cancer blood test by quantifying cancer gene mutations

Colorectal Cancer - Colorectal cancer screening research, recommendations presented at European cancer conference

Colorectal Cancer - Epidemiological features of colorectal cancer in Iran analyzed

Complementary & Alternative Medicine - Black tea induced tumor cell apoptosis of Ehrlich ascites carcinoma

Complementary & Alternative Medicine - Cancer patients' use of complementary and alternative medicine presented at European conference

Oncology - Recent findings in oncology described

Complementary & Alternative Medicine - Gamma-linolenic acid boosts effectiveness of Herceptin on cancer cells

Complementary & Alternative Medicine - Green tea extract cocktail blocks angiogenesis

Complementary & Alternative Medicine - Laminin receptor mediated suppressive effect of EGCG on Fc epsilon RI expression

Cytotoxicity - Diphtheria toxin fused to variant human interleukin-3 induces cytotoxicity of acute myeloid leukemia

DNA Research - Anticancer agent EZZ induces cell cycle arrest in S phase by inhibiting DNA replication

Oncology - Researchers provide details of new studies and findings in the area of oncology

Diagnostics - Biochemical marker health assessment tool now widely available

Diagnostics - Body mass index linked to prostate cancer detection rates in urologic patients

Diagnostics - Brain abscess and cystic brain tumor discriminated with perfusion MRI

Diagnostics - CD13 immunostaining used as diagnostic marker for hepatocellular carcinoma

Diagnostics - CT and FDG-PET image fusion impacted treatment planning and management of esophageal carcinoma

Diagnostics - Cancer core distribution diagnosed by extended transperineal prostate biopsy

Prostate Cancer - Research add new data to prostate cancer body of knowledge

Diagnostics - Diffusion-weighted imaging used to diagnose breast cancer

Diagnostics - Digital rectal examination cited as barrier to prostate cancer screening

Diagnostics - Early detection of hepatocellular carcinoma contributed to treatment efficacy

Diagnostics - Evaluation of telomerase subunits in urine as a biomarker of bladder cancer

Diagnostics - Feasibility of acoustic radiation force impulse imaging of abdomen confirmed

Diagnostics - Long screening time recommended for secondary tumors after curative treatment

Diagnostics - Lymphoscintigraphy shown to have limited usefulness in staging breast cancer

Diagnostics - MRI determined size of infiltrating lobular carcinoma

Diagnostics - MRI of axial skeleton enabled objective measurement of tumor response

Diagnostics - Nonpalpable breast lesions managed by alternatives to surgical excision

Diagnostics - Office-based cystoscopy and cytology correlated well with histologic diagnosis

Diagnostics - Predictive medicine company provides progress report on Prevu(x) and LungAlert

Diagnostics - Prostatic fossa biopsy not recommended in patients with normal clinical findings

Diagnostics - Radiation resistance in cervical cancer was associated with increased ICAM-3 expression

Diagnostics - Raman spectroscopy used for diagnosis of bladder and prostate cancer

Diagnostics - Researchers investigating use of imaging system for early lung cancer detection

Diagnostics - Semiautomated measurements of mesothelioma tumor thickness taken by CT scans

Diagnostics - Vector machines show accuracy in selecting appropriate gene extracts for cancer diagnosis

Diet & Nutrition - Barley varieties touted for cancer preventive effects

Disease Associations - Case of pemphigus vulgaris accompanied by multiple myeloma reported

Disease Associations - Familial associations between cancer sites implicate familial clustering

Disease Associations - Lung cancer metastasis induced acute pancreatitis

Drug Development - 5-caffeoylquinic acid identified as matrix metalloproteinase-9 inhibitor

Drug Development - CEO details progress on development of cancer drugs

Drug Development - Imidazole-4,5-dicarboxamide derivatives showed antiproliferative activity

Drug Development - Microtubule targeting agents sway tumor angiogenesis through hypoxia inducible factor-1

Drug Development - Preliminary results suggest drug may prevent breast cancer, treat vaginal atrophy