Oncology
Ephrlin receptor B2 upregulated in 75 gastrointestinal tumor types
Published in Cancer Weekly, November 22nd, 2005
In a recent study, researchers in Switzerland sought to "comprehensively evaluate ephrlin receptor B2 (EphB2) expression in normal and neoplastic tissues."
"EphB2 is a tyrosine kinase recently implicated in the deregulation of cell-to-cell communication in many tumors," explained A. Lugli and coauthors at the University of Basel Hospital. In their study, "experimental EphB2 protein expression was analyzed by immunohistochemistry on tissue microarrays that included 76 different normal tissues, >4,000 samples from 138 different cancer types, and 1,476 samples of colon...
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Source: Cancer Weekly (2005-11-22)
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