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Prognostics

Side effects during chemotherapy predicted tumor response in advanced colorectal cancer

Published in Cancer Weekly, November 29th, 2005

Side effects observed during chemotherapy could be used to predict tumor response in advanced colorectal cancer.

According to a recent article published in the British Journal of Cancer, "To investigate whether a relationship between chemotherapy-associated adverse events and treatment efficacy exists, we have analyzed the toxicity, objective response and survival data of 303 patients with advanced colorectal cancer. Patients were divided into 2 groups: the first with beneficial effect (I, n=245), and the second with progressive disease (II, n=58)."

"Differences in terms of incidence rates, type and severity of adverse events were analyzed...

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