Diagnostics
Proteomic analysis differentiated varying forms of childhood leukemia
Published in Cancer Weekly, November 29th, 2005
"Childhood acute lymphoblastic and myeloid leukemias are stratified into molecular and cytogenetic subgroups important for prognosis and therapy. Studies have shown that gene expression profiles can discriminate between leukemia subtypes," investigators in the United States reported.
"Thus, proteome analysis similarly holds the potential for characterizing different subtypes of childhood leukemia. We used surface-enhanced laser desorption/ionization time-of-flight mass spectrometry to analyze cell lysates from childhood leukemia cell lines as well as pretreatment...
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Source: Cancer Weekly (2005-11-29)
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