Susan Hasty, Publisher
Table of Contents . . . December 13th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Cancer Weekly | Other Publications
Cancer Risk Factors - Night work might be related to breast cancer risk
Cancer Therapy - Interferon treatment increases virotherapy for advanced hepatocellular carcinoma
Healthcare Costs - Taxane test-dose reduced cost associated with hypersensitivity reaction
Anemia - First long-term phase II study of CERA in renal patients shows control of anemia
Apoptosis - 2-cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) induced apoptosis in pancreatic cancer
Apoptosis - Biological stimuli of neuroblastoma cell response analyzed
Apoptosis - Micromolar taxol induced cell necrosis in HeLa cells
Apoptosis - Programmed cell death pathways targeted with experimental therapeutics
Apoptosis - Role of gangliosides in fenretinide-induced apoptosis of neuroblastoma examined
Breast Cancer - New findings in the area of breast cancer detailed
Birth Defects - Fruit fly research may revolutionize the study of birth defects secondary to methotrexate use
Bladder Cancer - New brochure helps patients understand radiation therapy treatment for bladder cancer
Borna Disease - CD8 T cells require gamma interferon to clear Borna disease virus from brain
Brain Tumors - Malignant neuroblastic tumors in adolescents reviewed
Brain Tumors - Malignant transformation of intracranial epithelial cysts into squamous cell carcinoma reviewed
Breast Camcer - First patients enrolled in three breast cancer studies for Modrenal
Breast Cancer - Recent findings in breast cancer described
Breast Cancer - Anti-estrogen-resistant breast cancer cells require activated protein kinase B/Akt for growth
Breast Cancer - Breast cancer cells are prone to apoptosis and growth arrest after protein silencing
Breast Cancer - Decoy chimera prevents urokinase receptor expression and breast cancer migration
Breast Cancer - Glut-1 expression is not predictive of race-specific breast cancer recurrence
Breast Cancer - New findings in the area of breast cancer described
Breast Cancer - Recent findings in breast cancer provide new insights
Breast Cancer - Pap test for the breast may identify disease 8 years earlier than mammogram
Breast Cancer - Researchers detail new studies and findings in the area of breast cancer
Breast Cancer - Study reveals many older women refuse follow-up breast cancer tests
Breast Cancer - The distance a patient lives from a radiation therapy facility impacts breast cancer treatment
Breast Cancer Complications - Tokuhashi score predicted life expectancy of breast cancer patients with spinal metastases
Breast Cancer Diagnosis - Hormonal etiology of breast cancer may help identify reversible biomarkers
Breast Cancer Research - Minority participation in health behavior research lags behind Whites
Breast Cancer Risk Factors - Breast cancer risk is not seen with certain estrogen metabolizing polymorphisms
Breast Cancer - Researchers report details of new studies and findings in the area of breast cancer
Breast Cancer Risk Factors - Decreased risk of breast cancer is seen in long sleepers
Breast Cancer Risk Factors - Estrogen-progestin combination increases breast cancer risk
Breast Cancer Risk Factors - Further study is needed to assess toremifene for chemoprevention
Breast Cancer Risk Factors - Similarity is seen between risk of breast cancer for passive and active smokers
Breast Cancer Risk Factors - Vitamin D, calcium intakes are related to lower mammographic density
Breast Cancer Screening - Age and race are likely determinants for mammography screening in elderly women
Breast Cancer Screening - CAD system proves accurate in identifying solid breast nodules
Cancer Therapy - Reports describe recent advances in cancer therapy research
Breast Cancer Screening - Digital mammography is more accurate in premenopausal or perimenopausal women
Breast Cancer Screening - Low-cost mailings of reminders increase repeat mammography interventions
Breast Cancer Screening - Preoperative lymphoscintigraphy is a useful tool for lymphatic mapping
Breast Cancer Survival - Age is not an independent prognostic factor for breast cancer survival
Breast Cancer Survival - Early physiotherapy after breast cancer surgery improves overall quality of life
Breast Cancer Therapy - Anastrozole decreases plasma lipids during neoadjuvant therapy
Cancer Therapy - Researchers' data advance cancer therapy research
Breast Cancer Therapy - Fat necrosis is common after breast-conserving surgery
Breast Cancer Therapy - Improved quality of life is seen with surgical treatment of breast cancer in the elderly
Breast Cancer Therapy - Medicinal herb induces cell growth arrest and apoptosis in breast cancer cells
Breast Cancer Therapy - Women switched to anastrozole treatment have improved event-free survival
Business & Finance - Brachytherapy seed producer stock quoted on OTCBB
Cancer Gene Therapy - HER-2 protein expression can be inhibited in ovarian cancer cells
Cancer Therapy - Researchers' findings advance cancer therapy research
Cancer Gene Therapy - Knockdown of c-Met by small interfering RNA inhibits hepatocellular carcinoma
Cancer Gene Therapy - Papillary thyroid carcinoma after recombinant GH therapy for Turner syndrome
Cancer Gene Therapy - Zebularine has antimitogenic and chemosensitizing effects in ovarian cancer
Cancer Invasion - Runx2 transcription factor regulates cancer cell metastasis and invasion
Cancer Prevention - Reports add new data to cancer prevention research
Cancer Therapy - Researchers' work adds to cancer therapy body of knowledge
Cancer Research - AKT cancer cell pathway demonstrates an unexpected function
Cancer Research - AmpliMed research shows preliminary evidence of antitumor activity
Cancer Research - Pediatric cancer research launches new research infastructure initiative
Cancer Research - Plant gene research may lead to the development of new oncology drugs
Cancer Research - Study demonstrates XL880 is generally well tolerated
Cancer Research - Testing for transitional cell carcinoma will improve outcome of dialysis patients
Diagnostics - Researchers describe findings in diagnostics studies
Cancer Research - The role of melatonin in cancer therapy is described as compelling
Cancer Research - Vascular disrupting agents combined with antiangiogenics offer tumor strategy
Cancer Risk Factors - Carriers of death receptor 4 haplotype 626C-683C linked to increased breast cancer risk
Cancer Risk Factors - Manipulating elevated LH levels in BRCA1 mutation carriers may reduce cancer risk
Cancer Risk Factors - Radiation exposure detected in personnel performing endoscopic retrograde cholangiopancreatography
Cancer Risk Factors - Relationship between sunbed use and cutaneous melanoma in Europe assessed
Diagnostics - Researchers publish new studies and findings in the area of diagnostics
Cancer Survival - Prognostic factors and survival in familial melanoma discussed
Cancer Therapy - A specific microdomain controls phenotypic behavior of bladder cancer cells
Cancer Therapy - Advantages and disadvantages of management strategies for stage I seminoma discussed
Cancer Therapy - Anti-Helicobacter pylori therapy used to treat MALT lymphoma
Cancer Therapy - Breast cancer drug may help combat weight loss during radiation therapy
Cancer Therapy - Chemoradiotherapy improved tumor control of nasopharyngeal carcinoma
Oncology - Research in oncology provides new insights
Cancer Therapy - Continuous endostatin infusions stabilize advanced cancer cases
Cancer Therapy - Curcumin reported to suppress growth of head and neck squamous cell carcinoma
Cancer Therapy - Data from phase I trial of XL999 establishing MTD presented at cancer conference
Cancer Therapy - Decreasing cancer-suppressing protein activity increases lifespan in fruit fly model
Cancer Therapy - Epigallocatechin-3-gallate blocks photocarcinogenesis by thwarting proangiogenic activity
Cancer Therapy - High dose 3DCRT when combined with long-term androgen deprivation benefited unfavorable prostate cancer
Oncology - Researchers detail new studies and findings in the area of oncology
Cancer Therapy - High dose L-asparaginase therapy evaluated for standard risk acute lymphoblastic leukemia
Cancer Therapy - High-content screening of cytotoxic agents achieved
Cancer Therapy - Inhibition of MDM2 proposed as therapeutic strategy for neuroblastoma
Cancer Therapy - Late effects of pelvic rhabdomyosarcoma in female survivors analyzed
Cancer Therapy - Lower dose of hyperfractionated whole brain radiation delayed neurotoxicity from chemoradiation in lymphoma patients
Cancer Therapy - Macrophage migration inhibitory factor marks hypoxia-dependent chemosensitivity
Cancer Therapy - Magnesium depletion enhanced cisplatin-induced nephrotoxicity
Cancer Therapy - Management strategies of non-seminomatous germ cell tumors discussed
Cancer Therapy - Meningoceles are induced by an antitumor agent in rat fetuses
Cancer Therapy - Older women who receive pelvic irradiation may be at increased risk for pelvic fractures
Cancer Therapy - Oncolytic viral therapy approved for head and neck cancer
Cancer Therapy - One thousandth prostate cancer patient treated with IsoCord at Kuopio University Hospital
Cancer Therapy - Positive Panzem NCD phase Ib clinical trial results reported
Cancer Therapy - Promising results presented for tubulin binding agent, ENMD-1198
Cancer Therapy - Radiotherapy advised after parotidectomy for parotid area lymph node metastases from squamous cell carcinoma
Cancer Therapy - Recent studies add new data to cancer therapy research
Cancer Therapy - Study highlights needed improvements in management of women with cancer
Cancer Therapy - Thrombospondin-1 helps cyclooxygenase inhibitors fight cancer invasion
Cancer Therapy - Use of imatinib mesylate in malignant mesothelioma demonstrated limited efficacy
Cancer Therapy - Valproate activates bovine leukemia virus gene expression and induces leukemia/lymphoma regression
Cancer Therapy - [I-131]MIBG and topotecan combination therapy evaluated for neuroblastoma
Cancer Vaccine - Anti-CD3 priming generates heterogeneous antigen-specific memory CD4 T cells
Cancer Vaccine - Exosomes prepared from heat-stressed CEA-positive tumor cells induce efficient CTL response
Cancer Vaccine - Trial to study response to adjuvant therapy with melanoma cancer vaccine
Cancer Vaccine - Tumor immunology and targeted immunotherapy for CNS malignancies are reviewed
Cancer Vaccine - Tumor-targeted viral vectors are delivered by hitchhiking on antigen-specific T cells
Carcinogenesis - Natural selection in neoplastic progression of Barrett esophagus analyzed
Caregiving - Perceptions of supportive communication in Chinese patients with cancer examined
Cervical Cancer - Current treatment for premalignant cervical lesions have proven safe & effective
Cervical Cancer - Defining disease extent has potential to improve cervical cancer survival
Cervical Cancer - Laminin-5 gamma 2 chain expression aids identification of invasive cervical lesions
Cervical Cancer - Reseachers offer review of treatment options for recurrent cervical cancer
Cervical Cancer - Researchers report new drug could change management options for cervical cancer
Cervical Cancer Risk Factors - Leukocyte antigen-A polymorphism decreases risk of cervical cancer in Chinese women
Cervical Cancer Risk Factors - Women with folate deficiency showed increased risk of cervical dysplasia
Cervical Cancer Screening - 2-D gel analysis provides protein expression profiles of squamous cell carcinoma tissues
Cervical Cancer Screening - Cervical neoplasia is hard to detect due to natural cervical topography
Cervical Cancer Screening - Follow-up of abnormal Pap smears is increased by use of outreach intervention
Cervical Cancer Screening - Hybrid Capture II test proves useful for detection of high-risk HPV
Chemotherapy - Clinical and nonclinical ispinesib results reported at AACR-NCI-EORTC meeting
Chemotherapy - Efficacy of cisplatin and platinum(IV) complexes unaffected by tumor microenvironmental factors
Chemotherapy - Etoposide, cisplatin, and irinotecan triplet used to treat advanced-stage small-cell lung cancer
Chemotherapy - First-line doxorubicin and docetaxel deemed effective in patients with metastatic breast cancer
Chemotherapy - Gemcitabine and treosulfan used to treat patients with metastatic uveal melanoma
Chemotherapy - Methylene blue considered for possible use in chemotherapy
Chemotherapy - Pemetrexed plus gemcitabine did not improve overall survival in pancreatic cancer patients
Chlamydia - Male circumcision could reduce Chlamydia trachomatis infection in female partners
Clinical Trials - Drugmaker plans filing strategy for orBec
Clinical Trials - Merck makes $1 million payment on start of DNA cancer vaccine trial
Clinical Trials - Phase I clinical trial begins for anticancer small molecule drug for leukemias
Clinical Trials - Phase II cancer trials designed using total and complete response endpoints
Clinical Trials - Preclinical data demonstrate potential of prodrug technology
Clinical Trials - STIR could be used as sole imaging technique for inflammatory lesions in spine
Clinical Trials - Study data on forodesine in leukemia treatment presented at hematology meeting
Collaborations - Companies announce license, collaboration agreement for assay technology
Collaborations - South Korean firm to commercialize humanized monoclonal antibody in Asia
Collaborations - Stem cell focused company, Wayne State collaborate on prostate cancer research
Colon Cancer - Cells with MUTYH gene mutations are defective in DNA damage binding and repair
Colon Cancer - Vegetables affect the expression of genes involved in anticarcinogenic processes
Colorectal Cancer - MGMT promoter methylation proposed as mediator of field defect in sporadic colorectal cancer
Complementary & Alternative Medicine - Antitumor-promoting effects of triterpene acids from Eriobotrya japonica leaves evaluated
Complementary & Alternative Medicine - Milk thistle used in treatment and prophylaxis of cancer
Complementary & Alternative Medicine - Role of laughter in medicine reviewed
DNA Research - Cells co-opt machinery for DNA strand repair, researchers report
DNA Research - DNA hypomethylating agents improve overall response rates in myelodysplastic disorders
Dendritic Cell Vaccine - Leukemia-derived dendritic cells can be generated from blood or bone marrow cells
Depression - New findings in the area of depression detailed
Dermatology - Normal human fibroblasts bolster melanoma-induced angiogenesis
Diagnostics - Abnormal gene promoter methylation detected in paraffin-embedded sputum from patients with NSCLC
Diagnostics - Abnormal patterns of antigenic expression detected in follicular lymphoma
Diagnostics - Ameloblastomas assessed using MRI and dynamic contrast-enhanced MRI
Diagnostics - Common ultrasonographic features of pilomatricoma described
Diagnostics - Diffusion-weighted magnetic resonance imaging needed to monitor disease progression of glioma
Diagnostics - EUS-guided FNA underutilized for lymph-node staging of non-small cell lung cancer
Diagnostics - Intraoperative ultrasonography used to detect small colonic polyps
Diagnostics - L-[methyl-C-11] methionine-positron emission tomography used to monitor treatment of glioma
Diagnostics - Lowering prostate-specific antigen threshold to 2.5 ng/mL not recommended
Diagnostics - MR imaging corresponded well with clinical examination of children with diffuse pontine tumors
Diagnostics - MR imaging used to assess leukoencephalopathy in children treated for acute lymphoblastic leukemia
Diagnostics - Monopolar radiofrequency devices in minimally invasive treatment of renal cell carcinoma compared
Diagnostics - N-2 laser excited autofluorescence spectroscopy used to diagnose formalin-fixed human breast tissue
Diagnostics - New disposable biopsy and tumor marking instruments introduced
Diagnostics - PET/CT used in head and neck tumor staging
Diagnostics - Percutaneous Harlow Wood needle biopsy diagnosed spinal lesions
Diagnostics - Prostate cancer screening prevalence differed between Caucasian and low-income African-American men
Diagnostics - QMSP gene patterns in urine sediment distinguished prostate cancer patients from control subjects
Diagnostics - Raman spectroscopy used for diagnosing larynx
Diagnostics - Recent findings illuminate research in diagnostics
Diagnostics - Reporting recommendations for tumor marker prognostic studies encouraged
Diagnostics - Risk of long-time arm morbidity after sentinel node biopsy (SNB) deemed minimal
Diagnostics - SN biopsy associated with lower midterm morbidity than ALN dissection for breast cancer
Diagnostics - Technically difficult endorectal ultrasounds increase the likelihood of inaccuracy
Diagnostics - Ultrasonographic characteristics helped differentiate between metastatic and benign lymph nodes
Digestive Tract Cancer - Higher heme iron intake is associated with risk of upper digestive tract cancer
Disease Associations - Cirrhosis associated with hepatic expression of Ki-67 and p53 protein
Disease Associations - Hypophosphatemic osteomalacia associated with multiple myeloma
Disease Associations - Oral lichen planus associated with human oral carcinogenesis
Disease Associations - Risk of malignant mesothelioma increased in testicular cancer survivors
Drug Delivery - Coformulated N-octanoyl-glucosylceramide improves liposomal doxorubicin efficacy
Drug Development - AEG35156 phase I oncology trial demonstrates target response in cancer patients
Drug Development - Boronic acid bioisostere of combretastatin A-4 synthesized
Drug Development - Data from phase I trial of XL647 presented at cancer conference; therapy generally well tolerated.
Drug Development - Data suggests EOquin as a radiation sensitizer slows tumor growth
Drug Development - Endothelial cell lactosylceramide is an upstream mediator of angiogenesis
Drug Development - Mapatumumab may be the first apoptosis modulator to live up to its potential
Drug Development - Mechanism of action of multi-functional class of defense proteins discussed
Drug Development - Phase I trial of temozolomide plus O-6-benzylguanine conducted for patients with malignant glioma
Drug Development - Positive preclinical data on camptothecin compound presented
Drug Development - Study shows INGN 241 and celecoxib combination kills breast cancer cells
Drug Development - Study to define the prevalence of the molecular marker N-cadherin among a variety of tumor types
Drug Resistance - Compounds transported by MRP1 could be predicted
Drug Resistance - Disrupting thrombin-PAR1 interaction may reduce tumor drug resistance
Endocrinology - Gonadotropin-releasing hormone analogs resensitize breast cancer cells to tamoxifen
Endometrial Cancer - Epidemiological risk factors define etiology of endometrial cancer
Endometrial Cancer Screening - MRI provides better performance in endometrial carcinoma than other modalities
Finance - Cancer-focused biotech reports third-quarter revenues of $58,000
Finance - Cancer-focused company reports revenue of $3.2 million for quarter
Finance - Cancer-focused technology services company announces $15 million private placement of common stock
Finance - Carbohydrate compound developer reports net loss of $1.68 million
Finance - ComfortScan maker announces third-quarter 2005 results, revenue of $65,000
Finance - Gastrointestinal cancer drug developer records loss of $0.06 per share
Finance - Imaging company reports third quarter revenue increase of 19%
Finance - Imaging company reports third-quarter revenue of $13.4 million
Finance - Molecular therapies firm reports financial results, Colgate-Palmolive alliance
Finance - Pharmaceutical company reports $5.8 million loss in first quarter
Finance - Radiation therapy developer announces second $4.5 M institutional financing
Finance - Small molecule therapeutics developer reports third quarter net loss of $5.6 M
Finance - Telomerase-focused company reports 2005 third-quarter financial results and events
Gastroenterology - Angiopoietins are amplified in human gastric cancer
Gastroenterology - Patients with cholangiocarcinomas bear response-predicting gene mutations
Gene Research - Acute lymphocytic leukemia gene profiles reveal transformation mechanisms
Gene Research - Androgen receptor genotype might affect prostate cancer outcome
Genetics & Genomics - At least two distinct intracellular gene products required for MLV infection
Geriatrics - Lobectomy for non-small cell lung carcinoma should not be denied to elderly based on age alone
Germ Cell Tumors - Retroperitoneal germ cell tumors studied
Glioma Vaccine - EphA2 glioma-associated antigen is target for glioma vaccines
Gynecology - Somatostatin may play a role in ovarian cancer angiogenesis
HIV/AIDS Research - Resistance selection study of PPL-100 shows potentially high genetic barrier
Head & Neck Cancer - Major cytokines reflect the angiogenesis of salivary gland adenoid cystic carcinoma
Health Promotion - Broccoli sprouts boost body's ability to eliminate cancer-causing toxins
Hematology - Marine product aplidine combats overexpressed VEGF in leukemia cells
Hepatitis B Therapy - Data show chronic hepatitis B vaccine shown to be generally well tolerated
Hepatitis B Vaccine - DNA vaccine adsorbed on microparticles enhances immune responses
Hepatitis B Virus - Hepatitis B surface antigenemia and alpha-fetoprotein detected from dried blood
Hepatitis D Virus - Hepatitis delta virus RNA genome evolution occurs during long-term replication
Hepatocellular Carcinoma - Protein up-regulation is a prognostic marker of hepatocellular carcinoma
Hepatology - High methotrexate doses cause changes to functional integrity of rat liver hepatocytes
Human Papillomavirus - Modulators regulated by HPV 16 E7 oncogene in HaCaT keratinocytes are identified
Imaging - Study uses imaging to see the immune system work at a cellular level
Infectious Diseases - Recent steroid therapy increases severity of varicella infections in children with ALL
Leukemia - Higher risk of mortality among Hispanics after hematopoietic stem cell transplantation examined
Lung Cancer Mortality - Smoking interventions are needed to continue favorable trend in lung cancer mortality
Lung Cancer Risk Factors - Lung cancer risk may be associated with endogenous and extraneous estrogen
Lung Cancer Survival - Expression of nuclear estrogen receptor beta on survival differs by gender
Marketing - Drug market for superficial bladder cancer predicted to increase 10% to 2012
Medical Devices - Volume shipments of Habib4x resection device resume
Melanoma - Focal adhesion kinase downregulation affects melanoma cell viability
Melanoma Vaccine - MAGE-3 protein vaccine is not effective in patients with metastatic melanoma
Mental Health - Age and obesity alter quality of life after gynecological surgery
Mental Health - End-stage renal disease patients with strong fighting spirit are less psychologically distressed
Mental Health - Psychoactive medications linked to risk of delirium in hospitalized cancer patients
Mergers & Acquisitions - Pharma company completes acquisition of Eyetech Pharmaceuticals
Merkel Cell Cancer - Case of Merkel cell carcinoma of the auricle reported
Metastatic Melanoma - Phase II study of talabostat in stage IV melanoma complete; results promising
Multiple Myeloma - Obesity may increase the risk of multiple myeloma
Multiple Myeloma - U.S. FDA issues approvable letter for Thalomid in treatment of newly diagnosed multiple myeloma
Mutagenesis - Chromium picolinate induces mutations in L5178Y mouse lymphoma cells
Myelodysplastic Syndromes - Vidaza maker withdraws E.U. marketing authorization application
Natural Products - Resveratrol targets proangiogenic proteins in human cancer cells
Nerve Damage - Effect of patient height on paclitaxel nerve damage investigated
Neuroblastoma - New gene research may help physicians customize care for pediatric neuroblastoma and other cancers
Neurology - Midkine is overly expressed in malignant peripheral nerve sheath tumors
Neuroscience - DEC1 is not a hypoxia marker in oligodendroglial neoplasms
Non-Hodgkin Lymphoma - Promising data reported from phase II clinical trial of FavId following Rituxan
Non-Small Cell Lung Cancer - Combination therapy demonstrates 35% reduction in lung cancer tumors
Obesity Complications - Increased risk in open retropubic radical prostatectomy is observed in obese men
Oncogenesis - Murine cells model the epithelial-stromal interactions of breast cancer
Oncology - 3'-Hydroxymyosmine may be a unique urinary biomarker for the carcinogen myosmine
Oncology - Curcumin prevents breast cancer metastasis to the lungs by potentiating chemotherapy
Oncology - Early growth response gene 1 is a key regulator of heparanase in tumor cells
Oncology - Lymphangiogenesis affirms lymph node metastasis risk in non-small cell lung cancer
Oncology - Pigment epithelium-derived factor prevents VEGF expression in osteosarcoma cells
Oncology - RT inhibitors downregulate cell proliferation and restore thyrotropin signaling
Oncology - Recent findings in oncology provide new insights
Oncology - Retroviral expression screening detects oncogenes in pancreatic ductal carcinoma
Oncology - Tumor-associated macrophages interact with melanoma to drive cancer progression
Ovarian Cancer - Genomics collaboration designed to improve outcome for ovarian cancer treatment
Ovarian Cancer - U.S. NIH researcher focuses on ovarian cancer screening
Pancreatic Cancer - Drug combination may extend survival of pancreatic cancer patients
Pancreatic Cancer - Favorable 2-year survival data from phase II clinical trial of GVAX vaccine for pancreatic cancer
Papillary Thyroid Carcinoma - Prognostic factors for papillary thyroid carcinoma identified
Papillomavirus Diagnostics - Hybrid Capture II and PCR-EIA are both suitable for papillomavirus detection
Pediatric Cancer - Adverse outcomes in Childhood Cancer Survivor Study (CCSS) not associated with minority status
Pediatric Leukemia - Case of acute myeloid leukemia presenting as spinal cord compression discussed
Personnel - Cancer-focused biopharma company announces corporate changes
Personnel - Gynecological oncologist named OB-GYN chair at Stanford
Personnel - Oncology-focused drug discovery firm appoints three senior executives
Personnel - Philip Frost, MD, PhD, named interim CEO of oncology company; board initiates external search
Personnel - Provenge maker announces organizational changes: Michelle Burris and Rick Hamm take on new duties
Personnel - Russell H. Ellison, MD, MSc, named vice president of clinical development
Pharmaceutical Research - Absolute bioavailability of oral vinorelbine in patients with solid tumors determined
Pharmaceutical Research - Maximum tolerated dose of PKI166 in patients with advanced solid malignancies determined
Pharmaceutical Research - Pharmacokinetics of S-1 plus cisplatin studied in patients with advanced gastric carcinoma
Pharmaceutical Research - Pirfenidone inhibits obliterative airway disease in mouse tracheal allografts
Pharmaceutical Research - Report shows oncology brands spend $76.8 million to launch
Pharmacokinetics - XK469 has low potential for active or toxic metabolites
Prognostics - Ocular complications in myelodysplastic syndromes can prognosticate leukemia
Prophylaxis - Use of selective estrogen receptor modulators in chemoprevention of breast cancer evaluated
Prostate Cancer - Availability of polyclonal hepsin antibody announced
Prostate Cancer - Biopharmaceutical company presents preclinical data on lead prostate cancer therapeutic candidate
Prostate Cancer - Endorectal coil improves prostate cancer imaging with 1.5 T MRI
Prostate Cancer - Outcomes from finasteride Prostate Cancer Prevention Trial discussed
Prostate Cancer - Phenoxodiol delays tumor progression in late-stage prostate cancer
Prostate Cancer - Pin1-targeted RNA interference stops angiogenesis and growth in prostate tumors
Prostate Cancer - RNA interference-directed knockdown inhibits prostate cancer
Prostate Cancer - Radiotherapeutic techniques for prostate cancer discussed
Prostate Cancer - Suicide gene expression kills PSA-expressing prostate tumor cells
Prostate Cancer Vaccine - HER-2/neu peptide vaccine prevents recurrence in high-risk prostate cancer patients
Proteomics - Downregulation of c-myc protein occurs by siRNA-mediated silencing of DNA-PKcs in HeLa cells
Quality of Life - Ambivalence over emotional expression linked to patient pain and quality of life
Quality of Life - Quality of life and illness perceptions surveyed among patients with recently diagnosed head and neck cancer
RNA Research - Mutations in microRNA transcripts are common and may have functional importance
Radiation Therapy - Low-dose radiotherapy safe and effective for lymphatic fistulas with lymphorrhea
Radiotherapy - Outcomes of I-125 radiotherapy for suspected small choroidal melanomas reviewed
Radiotherapy - Reports advance knowledge in radiotherapy research
Radiotherapy - Stereotactically guided fractionated re-irradiation used to treat recurrent glioblastoma multiforme
Rectal Cancer - Preservation of continence is feasible in resection of locally recurrent rectal cancer
Rectal Cancer - Surveillance of rectal cancer showed most recurrences occur within 5 years
Renal Cell Carcinoma - Recurrence-free survival in renal cell carcinoma patients predicted by tumor differentiation
Rheumatoid Arthritis - Golimumab shows promise in the treatment of rheumatoid arthritis in phase II trial
Salivary Gland Tumors - Cases of sublingual salivary gland tumors reviewed
Sexual & Reproductive Health - Pregnancy achieved in fertile partners of patients after prostate brachytherapy
Smoking Cessation - Pharmacotherapy for nicotine dependence is reviewed
Squamous Cell Carcinoma - Patterns of mandibular invasion by gingival squamous cell carcinoma examined
Stem Cell Research - Stem cell research developments promise innovative and cost-effective therapies
Stem Cell Transplantation - Hematopoietic allografts are safe in patients with previous fungal infections
Stem Cell Transplantation - Hematopoietic stem cell transplant patients frequently show mixed chimerism for a long period
Stem Cell Transplantation - Mesenchymal stem cells obtained after BMT or SCT originate from host tissue
Stem Cell Transplantation - Myeloablative conditioning is well tolerated by older patients receiving T-cell-depleted grafts
Surgical Technology - Hypopharyngeal reconstruction with laryngotracheal flap deemed feasible
Surgical Technology - Neurosurgical techniques for treating adult supratentorial oligodendrogliomas described
Surgical Technology - Partial nephrectomy could still be performed using open techniques with good results
Surgical Technology - Radical resection recommended over transanal excision for T1 adenocarcinoma of the rectum
Surgical Technology - Surgical limitations of sphenoorbital meningiomas described
Surgical Technology - Techniques for renal radiofrequency ablation outlined
Thyroid Cancer - Survival of thyroid cancer patients adversely affected by lymph node metastases
Thyroid Cancer - Zactima study elicits partial response in 2 of 11 patients
Tobacco Use - A new report states that many smokers fail to quit after receiving a cancer diagnosis
Tobacco Use - Physicians, researchers need to address the issue of patients who continue to smoke after a cancer diagnosis, study argues
Tobacco Use - Smoking cessation rates increased with peer-delivered smoking counseling
Transplant Medicine - P. aeruginosa is predominant organism causing pneumonia in orthotopic liver transplantation
Transplant Medicine - Beneficial effects of liver transplantation noted for hepatocellular carcinoma
Tubular Cancer Therapy - Radiation therapy reduces local failures, but long-term follow up is essential
Tumorigenesis - Selective evolutionary pressure drives tumor progression
Tumorigenesis - The cell-associated isoform of vascular endothelial growth factor reflects tumorigenesis
Uterine Fibroids - MRI shown to improve selection for nonsurgical treatment of uterine fibroids
Vaccine Efficacy - Neo-antigen response to keyhole limpet hemocyanin vaccines is reduced after chemotherapy
Virology - Withdrawal of lamivudine in patients can preclude hepatitis B reactivation
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