Oncology
Tumor-associated macrophages interact with melanoma to drive cancer progression
Published in Cancer Weekly, December 13th, 2005
"The objective of this study was to evaluate the role of TAMs in malignant melanoma progression, invasion and angiogenesis. We examined the levels of macrophage infiltration and monocyte chemotactic protein-1 (MCP-1), neovascularization and vascular endothelial growth factor-A (VEGF-A) in different Clark level melanomas with varying thicknesses and metastases," investigators in the United States report.
"The level of TAM density was significantly higher in thick (>0.75 mm) than thin ({{<=}}0.75 mm) melanomas, and positively correlated with melanoma...
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Source: Cancer Weekly (2005-12-13)
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