Apoptosis
Programmed cell death pathways targeted with experimental therapeutics
Published in Cancer Weekly, December 13th, 2005
According to a study from the United States, "Neuroblastoma is a pediatric solid tumor with high morbidity and mortality in association with particular high-risk biological and clinical features (such as MYCN proto-oncogene amplification or advanced tumor stage). Such high-risk neuroblastomas may be initially responsive to cytoreductive therapies, yet the majority will ultimately demonstrate de novo or acquired chemoresistance leading to tumor progression and death."
"Insight into the genetic alterations responsible for these phenotypes are beginning to be...
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Source: Cancer Weekly (2005-12-13)
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