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Cancer Weekly

Susan Hasty, Publisher

Table of Contents . . . December 20th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cancer Weekly | Other Publications

Breast Cancer - C-MYC Asn-11-Ser polymorphism associated with increased risk for familial breast cancer

Cancer Risk Factors - Mutations in androgen receptor gene linked to risk of testicular cancer

Cancer Therapy - Downmodulation of E1A protein expression used to aid design of cancer-selective adenoviruses

Cancer Therapy - Novel aminosubstituted xanthenones overcame multidrug resistance toward MES-SA/Dx5 cells

Complementary & Alternative Medicine - Ferulic acid and vitamins C and E use protects against skin cancer

Apoptosis -  Gleditsia sinensis fruit extract induced apoptosis in human carcinoma cells

Apoptosis - Increased antiapoptotic protein expression increases chemical susceptibility of skin tumors

Apoptosis - Nano neodymium oxide induced cell death in non-small cell lung cancer cells

Apoptosis - The BAD protein integrates survival signaling in tumor cells

Atrial Myxoma - Left atrial myxoma diagnosed by cardiac magnetic resonance imaging

Breast Cancer - New findings in breast cancer described

Barrett Esophagus - A new study provides first estimate of U.S. population affected by Barrett esophagus

Bladder Cancer - Biologic markers could help diagnose occupational bladder cancer

Bladder Cancer - Loss of CAR expression associated with aggressive disease

Bladder Cancer Vaccine - Moureau-Rio de Janeiro BCG strain reduces recurrence rate in bladder cancer

Breast Cancer -  CHEK2*1100delC allele imparts high risk for familial breast cancer

Breast Cancer - ADAM 12-mediated focal adhesion formation is differently regulated by integrins

Cancer Therapy - Findings describe new data in cancer therapy research

Breast Cancer - Breast CT is more comfortable and may be better for detecting tumors

Breast Cancer - Breast cancer detection viewed as risky behavior among older Latinas

Breast Cancer - Breast cancer screening sensitivity increased with patient age

Breast Cancer - Capecitabine/docetaxel combination therapy deemed cost effective in advanced or metastatic breast cancer

Breast Cancer - Company files 510(k) application with U.S. FDA on microendoscope for breast exams

Breast Cancer - Data reinforce confidence in fulvestrant endocrine therapy for advanced breast cancer

Cancer Therapy - Reports advance knowledge in cancer therapy research

Breast Cancer - Emotional patterns of partners and women with breast cancer are interdependent

Breast Cancer - GI metastasis occurs more in patients with lobular cancer than ductal cancer

Breast Cancer - New data illuminates research in breast cancer

Breast Cancer - Outpatient visits did not improve survival of breast cancer patients and increased costs

Breast Cancer - Overexpression of CC3/TIP30 is associated with HER-2/neu status in breast cancer

Cancer Therapy - Researchers describe findings in cancer therapy studies

Breast Cancer - Pennsylvania Governor signs bill making free mammograms available to women at high risk

Breast Cancer - Women who smoke prior to first pregnancy may have a higher risk of breast cancer

Breast Cancer Diagnosis - Hormone receptor profiles of breast cancers suggest different etiologies

Breast Cancer Diagnosis - Researchers studied self-blame attributions in women with newly diagnosed breast cancer

Breast Cancer Risk Factors - Oral contraceptive use in teenagers increases risk for early-onset breast cancer

Breast Cancer Screening - Digital vs. screen mammography: Phantom object detection is not enhanced by higher resolution

Cancer Therapy - Studies add new findings to cancer therapy body of knowledge

Breast Cancer Screening - Double reading with CAD increases sensitivity for cancer detection over single reading

Breast Cancer Screening - Review design influences percentages of missed interval breast cancers

Breast Cancer Survival - Lymphovascular emboli or invasion independently predicts survival in Indian women

Breast Cancer Therapy - Information provided by health providers could enhance adherence to tamoxifen therapy

Breast Cancer Therapy - Patients deem even small benefits worthwhile to undergo adjuvant chemotherapy

Breast Cancer Therapy - Radiation therapy after breast conserving surgery reduces risk of second tumors

Cancer Therapy - Studies advance knowledge in cancer therapy research

Breast Cancer Therapy - Successful lactation is possible after breast-conserving therapy

Breast Cancer Vaccine - Overexpression of protein fragment sensitizes MDA-MB-231 breast tumor cells to radiation

Breast Conservation - Breast conservation therapy treated suitable breast cancer patients

Bronchiectasis - Bronchiectasis developed in persons with skin lesions who ingested arsenic from drinking water

Business & Finance - Cancer-focused pharmaceutical company reports $11.5 million Q3 2005 net loss

Business Update - Biomedical company announces restructuring management agreement, retains Experigen

Diagnostics - Recent findings in diagnostics provide new insights

Cancer Drugs - Efficacy of doxorubicin improved via an enhanced intracellular delivery system

Cancer Gene Therapy - Adoptive transfer of CD4+ helper T cells induces tumor rejection

Cancer Gene Therapy - Clusterin is a therapeutic target for radiation sensitization in lung cancer

Cancer Gene Therapy - RNA interference in cervical cancer produces increased sensitivity to cisplatin

Cancer Gene Therapy - Transduced peripheral blood lymphocytes recognize fresh human tumor

Cancer Gene Therapy - Transfection suppresses tissue infiltration of B cell precursor leukemia cells

Diagnostics - Recent studies add new data to diagnostics research

Cancer Metastasis - Insulin-like growth factors stimulate lymphangiogenesis

Cancer Research - CAPE sensitizes CT26 colorectal adenocarcinoma to IR, does not affect marrow radioresponse

Cancer Research - Obese youth with hyperglycemia related to lymphoblastic leukemia have high risk of complications

Cancer Research - Patients with lipoblastoma/lipoblastomatosis should be followed for more than 3 years

Cancer Research - Scientists are closer to a new technique to detect cancer before symptoms appear

Cancer Research - Serum levels of soluble ICAM-1 and VCAM-1 can be used to predict preclinical cancer

Diagnostics - Reports add new data to diagnostics research

Cancer Research - Vitamin E pre-treatment reduces the degree of oxidative stress induced by NDEA

Cancer Research - p53 Molecular bridge distruption may produce clumps, suggesting link to adrenocortical carcinoma

Cancer Risk Factors - Colorectal cancer incidence related to asbestos exposure

Cancer Risk Factors - Dietary iron, zinc, and calcium implicated with risk of lung cancer

Cancer Risk Factors - Estradiol and progesterone levels have no effect on micronucleus assay variability

Cancer Risk Factors - FASL-844C polymorphism associated with increased risk of cervical cancer

Diagnostics - Reports describe recent advances in diagnostics research

Cancer Risk Factors - Former breast/ovarian cancer patients have high risk of familial genetic mutation

Cancer Risk Factors - Long-term environmental tobacco smoke exposure linked to risk of adult leukemia

Cancer Risk Factors - Meta-analysis conducted to identify risk factors for cutaneous melanoma

Cancer Risk Factors - Relatives of women with lobular breast cancer linked to higher risk for breast cancer

Cancer Screening - Abdominal CT plus mammogram improves cancer detection in IVTE patients

Cancer Therapy - 130 mg*m-2 oxaliplatin is optimal multidrug dose with 5-fluorouracil and leucovorin

Diagnostics - Researchers' findings advance diagnostics research

Cancer Therapy - Administration of propolis and its polyphenolic compounds delayed tumor formation and growth

Cancer Therapy - Analysis of ABCC1 clarifies leukotriene C4 binding sites

Cancer Therapy - Anthracyclines plus fluoropyrimidines well tolerated and active in advanced breast cancer patients

Cancer Therapy - Bendamustine used to treat patients with relapsed or refractory chronic lymphocytic leukemia

Cancer Therapy - Breast tumor cell growth attenuated by conjugated linoleic acid

Cancer Therapy - Cancer drug AT-101 demonstrates manageable toxicity and early evidence of clinical activity

Diagnostics - Studies add new findings to diagnostics body of knowledge

Cancer Therapy - Chromosomal deletions in B-cell lymphoma identify candidate tumor suppressor genes

Cancer Therapy - Continuous exposure to low-dose cisplatin induced apoptosis in rat hepatoma AH-109A cells

Cancer Therapy - Data advance knowledge in cancer therapy research

Cancer Therapy - Dynamic MRI clarifies the effect of chemotherapy on tumor vascularity

Cancer Therapy - Extracellular matrix protein fragments offer new avenues for stopping tumor angiogenesis

Diagnostics - Studies advance knowledge in diagnostics research

Cancer Therapy - Genasense reported to enhance preclinical activity of Tarceva with intermittent dosing schedule

Cancer Therapy - HER2/neu may play a role in the tumorigenesis of synovial sarcoma

Cancer Therapy - HuN901-DM1 use in phase I trial results in 15-week remission for lung cancer patients

Cancer Therapy - IL-17 enhances angiogenic activity and growth of non-small cell lung cancer

Cancer Therapy - Intraoperative radiation therapy may be beneficial in recurrent ovarian cancer

Cancer Therapy - Irradiation down-regulates SMT3A gene expression in nevoid basal cell carcinoma

Lung Cancer - Studies add new findings to lung cancer body of knowledge

Cancer Therapy - Mastoparan could be administered via a tumor selective delivery system

Cancer Therapy - New chemotherapy and radiotherapy combinations used in the management of gastric cancer

Cancer Therapy - PS-341 did not improve condition in patients with metastatic pancreatic adenocarcinoma

Oncology - Reports add new data to oncology research

Cancer Therapy - Targeted blockade of p38 alpha MAPK helps hypericin-based photodynamic therapy fight cancer

Cancer Therapy - Telomerase antagonists inhibit tumor growth and increase hepatoma chemosensitivity

Cancer Therapy - Transurethral resection and radiochemotherapy used to treat locally advanced bladder cancer

Oncology - Researchers publish new studies and findings in the area of oncology

Cancer Therapy - Treatment including gemcitabine and vinorelbine is proposed for non-small cell lung cancer

Cancer Therapy - Updated PXD101 phase I results presented at the AACR-EORTC-NCI conference

Cancer Therapy - Various chemoradiotherapy regimens in rectal cancer compared

Cancer Vaccine - Electrical charge promotes viability and physiology of dendritic cells

Cancer Vaccine - Epitope from cancer testis antigen was presented by dendritic cells to CD4+ T cells

Cancer Vaccine - Mechanism of DNA topoisomerase poisoning was investigated

Carcinogenesis - A cellular model recreates the transformation of oral-esophageal cancer cells

Carcinogenesis - Hormesis and dose-response-mediated mechanisms in carcinogenesis discussed

Cell Biology - Interferring with cells' hypoxia mechanisms may enhance solid tumor treatment efficacy

Cervical Cancer - Gene cluster associated with HPV expression may be biomarker for cervical cancer

Cervical Cancer - Interaction of host and viral risk factors required for development of cervical carcinoma

Cervical Cancer - Studies advance knowledge in cervical cancer research

Cervical Cancer Screening - Participant factors were identified in a cervical cancer screening program

Cervical Cancer Screening - Single-visit program for women with abnormal Pap tests increases follow-up rate

Cervical Cancer Vaccine - High prevalence of HPV-16 found was in squamous intraepithelial lesions in Portuguese women

Cervical Cancer Vaccine - Vaccine against human papillomavirus in adolescents reaches market in 2006

Chemotherapy - Etoposide, doxorubicin and cisplatin plus mitotane used to treat advanced adrenocortical carcinoma

Chemotherapy - Imatinib and hydroxyurea used to treat progressive glioblastoma multiforme

Chemotherapy - Weekly paclitaxel used to treat patients with advanced melanoma

Clinical Trials - Clinical trial data on organic arsenic shows safety and activity at higher doses

Clinical Trials - Public awareness about cancer risk factors could bias case-control studies

Clinical Trials - Roswell Park Cancer Institute named a site for GCS-100 phase I/II multiple myeloma clinical trial

Clinical Trials - Study to evaluate combination therapy for MDS or AML

Clinical Trials - Updated trial data on therapy for advanced ovarian cancer is promising

Collaborations - German companies collaborate on monoclonal antibodies to human GPCR cancer targets

Collaborations - Technology company enters agreement with Eli Lilly & Co.

Collaborations - Validation strategy for prostate biomarkers reaffirmed

Colorectal Cancer - Effect of 2-week wait rule on presentation of colorectal cancer evaluated

Colorectal Disease - Prophylactic colectomy recommended in patients with MYH-associated polyposis

Complementary & Alternative Medicine - Consumption of soy food associated with lower risk of prostate cancer

Complementary & Alternative Medicine - Diterpenoids from the Chinese herb Rabdosia rubescens affected NF-kappa B in breast cancer

Complementary & Alternative Medicine - Glycolipids fraction from spinach displayed anticancer activity

Complementary & Alternative Medicine - Pomegranate fruit juice proposed for chemoprevention and chemotherapy of prostate cancer

Congenital Mesoblastic Nephroma - MRI could not be used to stage congenital mesoblastic nephroma

DNA Research - Telomerase-based approach detects natural cell-mediated cytotoxic activity

Dendritic Cell Vaccine - Melanoma cell necrosis facilitates transfer of antigens onto dendritic cells

Dendritic Cell Vaccine - Natural killer dendritic cell cross-talk is effective for cancer immunotherapy

Developmental Biology - Werner syndrome is associated with gene misregulation

Diagnostics - Criteria of diagnosis of oligodendrogliomas compared between WHO and Sainte-Anne classifications

Diagnostics - Dark-lumen magnetic resonance colonography used to diagnose patients with suspected sigmoid diverticulitis

Diagnostics - Diagnostics company announces breakthrough in human papillomavirus testing

Diagnostics - Findings advance knowledge in diagnostics research

Diagnostics - High-frequency ultrasound probe sonography determined depth of invasion of early gastric cancer

Diagnostics - Optical spectroscopy differentiated between benign and malignant renal tissues

Diagnostics - Perfusion MR imaging for initial diagnosis and follow-up of brain tumors discussed

Diagnostics - Positive nestin-immunoreaction used to diagnose clear cell tumors in adrenal glands

Diagnostics - Radiographic techniques for detection of lung adenocarcinoma lesions compared

Diagnostics - Revised instrument to assess perceived needs of men diagnosed with prostate cancer validated

Diet & Exercise - Study demonstrates the role of exercise, melatonin in reduced breast cancer risk

Diet & Nutrition - Diet rich in fruits and vegetables may improve health and lower medical costs in old age

Diet & Nutrition - Gastrointestinal malabsorption leading to malnutrition and weight loss is reviewed

Diet & Nutrition - Review shows that providing diet advice leads to a modest drop in cardiovascular risk factors

Disease Associations - Graft-versus-leukemia effect associated with acute and chronic graft-versus-host disease

Disease Associations - Patients with Wilms tumor associated with low risk of end stage renal disease

Disease Associations - Prostate cancer patients should be assessed for likelihood of gynecomastia

Disease Associations - Relationship between obesity and pediatric oncology discussed

Drug Development - Biopharma company expecting milestone payment from Bristol-Myers Squibb for cancer drug

Drug Development - Ceramide kinase may be a target for new class of anti-inflammatory compounds

Drug Development - Development program expanded for cancer drug humanized EGFr inhibitor nimotuzumab

Drug Development - Global development plans made for advancing eniluracil into phase III by mid 2007

Drug Development - Interim phase I data indicate RH1 in cancer patients is well tolerated

Drug Development - Radiopharmaceutical unit increases focus on radioactive iodine products

Drug Development - U.S. FDA grants fast track status to drug for head and neck squamous cell carcinoma

Drug Resistance - Proangiogenic signals help pancreatic cancer evade therapy

Endocrinology - ERTargetDB integrates information on transcription regulation of estrogen receptor target genes

Endocrinology - Estrogen and tamoxifen influence the angiogenic stance of breast cancer

Endometrial Cancer Therapy - Carboplatin plus paclitaxel is attractive treatment strategy for endometrial carcinoma

Environmental Health - Occupational exposure to pesticides linked to risk of non-Hodgkin lymphoma

Environmental Health - Potential toxicological risk from water ingestion in area affected by tanneries assessed

Environmental Health - Scientists find that PCBs and furans may factor into the risk of developing non-Hodgkin lymphoma

Environmental Health - Somatic and germ cell DNA damage in acrylamide-treated mice depends upon CYP2E1 activity

Epidemiology - Self-reported height and weight indicates higher BMI, does not increase cancer risk

Facilities - Cancer-focused biotech company relocates headquarters

Finance - Biopharma reports third-quarter revenues of $1.3 million

Finance - Cancer screening systems company reports reduction in operating loss

Finance - Developer of peptide-based therapies announces third-quarter net loss of $1,618,521

Finance - Drug developer reports third-quarter 2005 results: net loss is $3,631,000

Finance - Grant enables Long Island, NY, hospital to plan $45M research facility

Finance - Quadramet maker revises third-quarter results; net loss reduced by $703,000

Fitness & Wellness - Oncologists recommend exercise to patients with cancer

Gastric Cancer - Cyclooxygenase-2 is an independent prognostic factor in gastric cancer

Gastric Cancer - Double cancer of the stomach and esophagus with situs ambiguus with polysplenia reported

Gastritis - VEGF and angiogenesis stimulate Helicobacter pylori-related gastritis

Gastroenterology - Specific genetic changes may govern tumor angiogenesis in colon cancer

Gene Research - Administration of caffeine or green tea affected mutation profile in murine p53 gene

Genetics & Genomics - Ink4c and Ptch1 genes collaborate to suppress development of medulloblastoma

Geriatrics - Association between aging and cancer explored

Glioblastoma Multiforme - Cintredekin besudotox trial reaches criterion for the second futility statistical analysis

HIV/AIDS Coinfection - HHV8 enhances HIV replication in acutely infected cells and induces reactivation

Head & Neck Cancer - Coexpressed molecular markers identify progression risk in patients with oral cancer

Head & Neck Cancer - Combination radiation-chemotherapy may preserve speech better than surgery in head and neck cancer

Healthcare Access - Care Trust backs down on decision not to provide a life-saving drug to a single mother

Healthcare Costs - Costs of treatment intensification for head and neck cancer overviewed

Hepatitis B Virus - Lamivudine may prevent liver failure in HBV-related hepatocellular carcinoma

Hepatitis B Virus - Mannose-binding lectin may be therapeutic in chronic hepatitis B virus infection

Hepatitis C Virus - HCV-associated liver B cell clonalities do not carry a chromosomal translocation

Hepatocellular Carcinoma - Thalidomide amplifies the effects of paclitaxel in liver cancer models

Herpesvirus - HHV-8 is not associated with the pathogenesis of gastrointestinal stromal tumors

Hodgkin Lymphoma - Monitoring late effects of treatment in adolescents with Hodgkin lymphoma advised

Hormone Receptors - Hormone receptors predict HER2/neu status in older but not younger women

Human Papillomavirus - Hybrid capture 2 assay proves more sensitive than PCR assay for HPV DNA testing

Hypoxia - Activation of integrated stress response is required for tumor cell adaptation to hypoxia

Imaging - Gastrography used to evaluate gastric lesions

Imaging - Guidelines for computed tomography dose reduction in children discussed

Imaging - New ImageChecker Version 8.1 Mammography CAD system introduced

Imaging - Positron emission tomography deemed cost effective in most jurisdictions in Canada

Imaging - Process begun with U.S. FDA for approval of digital mammography imaging system

Imaging - Studies describe new findings in imaging research

Immunotherapy - JNK1 is essential for CD8+ T cell-mediated tumor immune surveillance

Influenza Vaccine - Children with solid tumors should receive yearly influenza immunizations

Influenza Vaccine - Conserved influenza A epitopes in humans and transgenic mice are described

Information Technology - Electronic clinical data capture solution to be piloted by U.K. National Cancer Research Network

Intraocular Metastatic Tumors - Testicular embryonal cell carcinoma may metastasize to the eye

Leukemia - Studies advance knowledge in leukemia research

Liver Cancer - Extended survival of hepatocellular carcinoma patients studied

Liver Cancer - New radiation treatment for liver cancer focuses on tumor not the whole liver

Liver Cancer - Percutaneous radiofrequency ablation of renal tumors assigned CPT code

Lung Cancer - Arginase I in myeloid suppressor cells is induced by COX-2

Lung Cancer - Carcinoembryonic antigen and neuron-specific enolase used to diagnose malignant effusion

Lung Cancer - Delays in specialist diagnosis and treatment were not correlated with worse lung cancer prognosis

Lung Cancer - Non-small cell lung cancer cells display alteration of biological pathways

Lung Cancer - Research add new data to lung cancer body of knowledge

Managed Healthcare - Awareness of diagnosis among hospitalized cancer patients in Greece surveyed

Managed Healthcare - Quality of pathology department affects staging and management of colon cancer

Marketing - GSW Worldwide to lead Saforis launch campaign for MGI Pharma, Inc.

Mastectomy - Radical mastectomy increases risk of treatment failure in high-grade primary breast lymphoma

Medical Devices - Accuracy of forceps biopsies to uncover polypoid lesions of the colon evaluated

Medical Devices - AutoMed 3400C Ambulatory Infusion Pump introduced to deliver continuous chemotherapy

Medical Devices - Personal electronic ultraviolet radiation dosimeter in a wristwatch developed

Medical Devices - Real-time brachytherapy implantation method lowers risk of pulmonary seed migration

Melanoma - Altered E prostanoid (EP) receptor expression implicated in development of melanoma

Melanoma - Expression of activated Akt and PTEN in malignant melanomas did not relate to clinical outcome

Melanoma - Increasing incidence of lentigo maligna melanoma subtypes reported

Melanoma - Melanomas contain a stem cell subpopulation that contributes to heterogeneity and tumorigenesis

Melanoma - Outcome of patients with melanoma and central nervous system as exclusive site of disease described

Melanoma - Risk, tumor characteristics, and mortality in adult twins with malignant melanoma analyzed

Mergers & Acquisitions - Developer of anticancer drugs announces transaction to become private company

Mergers & Acquisitions - Pharma company acquires Survac ApS for EUR 11 million

Metastases - Metastatic choroidal tumors indicated terminal status of underlying malignancy and short survival time

Metastatic Disease - Management of metastatic disease discussed

Nasopharyngeal Carcinoma - Radiotherapy does not impair retro-cochlear auditory pathway function

Non-Small Cell Lung Cancer - Biosciences company announces positive interim results from a phase I trial of Talotrexin

Nosocomial Infections -  Pichia anomala fungemia outbreak in a pediatric ICU in Brazil caused by a single strain

Obesity Complications - Large cohort study shows obesity increases cancer risk for variety of cancer types

Oncology - Lymphangiogenesis is diminished within breast cancer tumors

Oncology - Lymphangiogenesis is not a conduit for pancreatic ductal adenocarcinoma lymph node metastasis

Oncology - New data illuminates research in oncology

Oncology - VEGF may be a prognostic indicator in head and neck squamous cell carcinoma

Orbital Neoplasms - Mortality following exenteration for malignant tumors of the orbit examined

Ovarian Cancer - Modifying inclusion criteria for ovarian cancer patients may improve outcomes data

Ovarian Cancer - Molecular pathogenesis of ovarian borderline tumors discussed

Ovarian Cancer - Promoter methylation inactivates genes in ovarian clear cell adenocarcinoma

Pain Management - Buprenorphine used to control cancer pain

Pain Management - Coonrad-Morrey total elbow arthroplasty used to palliate pain in patients after resection

Pain Management - Efficacy and side effects of opioids for cancer pain treatment evaluated

Pain Management - Multicenter clinical trial of peptide therapeutic for severe cancer pain initiated

Pancreatic Cancer - EGFR-inhibitor receives approval in U.S. for pancreatic cancer

Pancreatic Cancer - Elastase modulates endostatin production in pancreatic cells

Pancreatic Cancer Therapy - Dehydroxymethylepoxyquinomicin and tumor necrosis factor-alpha used to treat pancreatic cancer

Pancreatic Cancer Therapy - Lupeol induced apoptotic death of human pancreatic adenocarcinoma cells

Patents - Connecticut company receives Canadian patent for apparatus and method for isolated pelvic perfusion

Patient Care - Benefits from short-term contact with general practitioner following cancer treatment assessed

Patient Care - Information needs of patients with incurable cancer discussed

Pelvic Reconstruction - Vertical rectus abdominis musculocutaneous flap is reliable tissue source for neovagina

Personnel - CEO Richard M. Levy to retire from cancer therapy systems company

Personnel - Dr. Robert Bast joins scientific advisory board of Xolair developer

Personnel - J. Kris Piper named VP, regulatory affairs, of oncology-focused drug company

Personnel - Medical device company names Frank Benick as chief financial officer

Personnel - Medical device company promotes Constantine to SVP marketing, sales and new product development

Pertussis Vaccine - Antibodies directed against pentasaccharide-tetanus toxoid conjugate exhibit anti-endotoxin activity

Pharmaceutical Research - Precursor cells signal optimal doses of metronomic chemotherapy

Produce Licensing - Clarient, partner, announce licensing agreement

Prognostics - High p53 expression associated with poorer prognosis in primary melanoma

Prognostics - MCM4 expression prognosticated esophageal cancer

Prognostics - Mitotic activity index and fibrotic focus used to prognosticate invasive breast cancers

Prognostics - rDNA methylation predicted progression-free survival of ovarian cancer patients

Prostate Cancer - Current thoughts shared on the role of androgen receptor in prostate cancer progression

Prostate Cancer - Interim results show PSA response from drug with docetaxel, prednisone in HRPC

Prostate Cancer - Prostate cancer cell line may help provide better model for disease study

Prostate Cancer - Radiation exposure risks associated with iodine-125 brachytherapy seeds are limited

Prostate Cancer - Scientists identify molecule that may contribute to prostate tumor formation growth

Prostate Cancer - Screening for prostate cancer could help detect earlier stage tumors and improve patient outcome

Proteomics - Recent studies add new data to proteomics research

Quality of Life - No difference in quality of life found between patients with neobladder and control population

Quality of Life - The quality of life in survivors of childhood craniopharyngioma was evaluated

Radiology - Prenatal irradiation induces genomic instability in hemopoietic cells

Radiotherapy - ConPas used as alternative to IMRT for bilateral neck treatment

Radiotherapy - Conventional irradiation compared to hypofractionated irradiation for breast cancer patients

Rectal Cancer Therapy - Gender and surgery type influence quality of life assessment after rectal surgery

Renal Cell Carcinoma - Coramsine receives orphan drug designation from U.S. FDA

Skin Cancer Vaccine - Melanoma progression occurs despite high levels of CD8+ T cells

Squamous Cell Carcinoma - Erbitux plus radiotherapy resulted in a 19.7-month median survival improvement

Squamous Cell Carcinoma - Study shows elecroporation plus bleomycin more effective treatment for head and neck cancer

Stem Cell Research - Activity of embryonic stem cell genes reported to be elevated in testicular and breast cancers

Stem Cell Transplantation - Acute GVHD grade correlates with the concentration of serum rabbit IgG prior to SCT

Stem Cell Transplantation - Autologous SCT with high-dose melphalan is safe for patients with multiple myeloma

Stem Cell Transplantation - Two activating donor KIRs protects against leukemic relapse after related HLA-identical HSCT

Stem Cell Transplantation - Viral transmission risk in BMT is lower with umbilical blood stem cells than with BM cells

Surgical Technology - Embolization recommended as initial treatment of choice for large or symptomatic AMLs

Surgical Technology - Hybrid video-assisted thoracic surgery offered as an alternative approach for lung cancer

Surgical Technology - Laparoscopic guidance improves axillary dissection outcome

Surgical Technology - Management of large cranial osteoma depends on shape and growth pattern of tumor

Surgical Technology - Per anum intersphincteric rectal dissection limits outlined

Surgical Technology - Superficial parotidectomy used to treat parotid tumors with acceptable morbidity

Surgical Technology - Surgical strategies for cervical and endometrial carcinoma discussed

Surgical Technology - Validity of clinical pathway for laparoscopic colorectal surgery assessed

Testicular Cancer - Infertile men with abnormal semen analyses linked to greater incidence of testicular cancer

Uveal Melanoma - Population-based incidence of uveal melanoma in various races and ethnic groups analyzed

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