Drug Development
Novel cis-diamminedichloroplatinum(II) analogues inhibited cancer cell growth
Published in Cancer Weekly, December 27th, 2005
"Preparations of cis- and trans-platinum(II) complexes of diethyl (pyridin-4-ylmethyl) phosphate (4-pmOpe) have been described. These complexes were identified and characterized by far-IR, H-1 NMR, C-13 NMR, P-31 NMR and Pt-195 NMR and microanalyses," investigators in Poland reported.
"The crystal and molecular structure of trans-platinum(II) complex i.e., trans-[PtCl2(4-pmOpe)(2)] was determined by the X-ray diffraction. Novel complexes were assayed for their potential antiproliferative effect against HT 29 (colorectal adenocarcinoma) and A 549 (non-small cell...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
Source: Cancer Weekly (2005-12-27)
More Articles from Cancer Weekly
- Diet & Nutrition
Use of dietary supplements might have adverse interactions with chemotherapy - Gene Research
Use of bioinformatics and genome analysis aids in discovery of new cancer therapeutics - Acoustic Neuromas
New procedure allows those suffering from a specialized brain tumor to preserve their hearing - Alzheimer Disease
Microglial cell uptake of amyloid beta is promoted by protein up-regulation - Antisense Technology
Promoter hypomethylation marks the progression of chronic myeloid leukemia - Apoptosis
Cisplatin activates Akt in small cell lung cancer cells and attenuates apoptosis - More from this issue of Cancer Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
