Imaging

Epithelial cell migratory behavior can be modeled and imaged

Published in Cancer Weekly, January 3rd, 2006

In a recent article, researchers in France reported on a three-dimensional (3D) culture model and computer-assisted videomicroscopy to analyze migratory behavior of noninvasive and invasive bronchial epithelial cells.

"To date, most of the studies in the field of cell migration have been applied to two-dimensional (2D) models. To mimic the 3D conditions similar to those observed in vivo during tumor invasion, we developed a 3D model of cell migration in which cells were embedded in a collagen I matrix placed in a double-compartment chamber."

"Using time-lapse videomicroscopy and interactive cell tracking in a four-dimensional data set, we determined...

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Source: Cancer Weekly (2006-01-03)

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