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Liver Metastases

Hepatic intraarterial Y-90-DOTA-lanreotide deemed safe palliative treatment of liver metastases

Published in Cancer Weekly, January 3rd, 2006

Hepatic intraarterial yttrium 90 (Y-90) tetraazacycloclodecane tetra-acetic acid (DOTA) was deemed a safe palliative treatment of liver metastases.

Researchers in England conducted a study "to prospectively evaluate the safety and effectiveness of hepatic intraarterial injection of Y-90-DOTA-lanreotide as a treatment for patients with progressive large-volume somatostatin receptor-positive liver metastases from neuroendocrine tumors. The study was local ethics committee approved, and all patients gave informed consent. Twenty-three patients (13 men, 10 women; age range, 21-69 years; median age, 57 years) with histologically proved large-volume liver metastases from...

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