Breast Cancer

Oophorectomy reduced risk of breast cancer in carriers of BRCA1 mutations

Published in Cancer Weekly, January 3rd, 2006

Oophorectomy reduced the risk of breast cancer in carriers of BRCA1 mutations and possibly also BRCA2 mutations.

According to recent research from Canada, "The purpose of this study was to estimate the extent of protection offered against breast cancer by prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations and to determine to what extent risk reduction varies with age at oophorectomy, age at diagnosis, and time elapsed since surgery."

"We analyzed 1,439 patients with breast cancer and 1,866 matched controls derived from a registry of BRCA1 and BRCA2 carriers. We estimated odds ratios (ORs) of breast cancer for having had a bilateral...

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Source: Cancer Weekly (2006-01-03)

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