Cancer Weekly

Cancer Risk Factors - Effects of gestational mutations on cancer risk assessed by mathematical formula

Diet & Nutrition - Human milk found to protect against gastric cancer

Disease Associations - Family history of hematopoietic malignancy related to higher risk of lymphoma

Head & Neck Cancer - Betel quid chewing may contribute to pharyngeal and laryngeal carcinogenesis

Acute Lymphoblastic Leukemia - European study confirms efficacy of clofarabine in pediatric patients with ALL

Acute Myeloid Leukemia - Acute myeloid leukemia blasts regularly express PRR1 and PRR2

Acute Myeloid Leukemia - Scientists may be able to use novel antibody to target specific cells leading to AML

Acute Myeloid Leukemia - Study of childhood AML yields 1-year survival rates of almost 90%

Anal Cancer - VRAM flap reconstruction prevented wound complications during abdominoperineal resection

Angiology - Fatty acid-mediated iron translocation is a mechanism of oxidative injury

Cancer Therapy - New research in the area of Cancer Therapy detailed

Antibiotics - Antibiotics could be withheld in neutropenic cancer patients with fever

Antioxidants - Researchers publish new studies and findings in the area of antioxidants

Antisense Technology - Antisense oligonucleotide induces apoptosis and enhances chemosensitivity in prostate cancer cells

Apoptosis - Cancer cells activate apoptosis in response to dehydrogenase expression

Apoptosis - Clonogenic tumor growth inhibited by Smac

Apoptosis - Doxorubicin induces apoptosis in germ line stem cells in the immature testis

Cancer Therapy - Recent findings in Cancer Therapy provide new insights

Apoptosis - HIN-1 identified as inhibitor of cell growth and invasion

Apoptosis - Ircinin-1 induced apoptosis in human melanoma cells

Apoptosis - Normal cells produce and release an apoptosis-inducing cytokine

Apoptosis - Recent studies add new data to apoptosis research

Autoimmune Diseases - Cytotoxic antigen induces autoimmune hypophysitis in cancer patients

Basal Cell Cancer - Basal cell carcinomas presented with unusual histologic patterns

Cancer Therapy - Researchers report details of new studies and findings in the area of Cancer Therapy

Bladder Cancer - Proteome analysis of gelatin-bound urinary proteins diagnosed bladder cancers

Bladder Cancer - Risk factors for prostatic urethral involvement in transitional cell carcinoma of bladder examined

Brain Cancer - Plasmalemmal vesicle associated protein-1 highlights brain tumor angiogenesis

Brain Metastases - Analysis finds Efaproxyn extends survival in brain metastases originating from breast cancer

Brain Tumors - Intensified induction chemotherapy yields positive results in pediatric brain tumors

Breast Cancer - Advanced breast biopsy instrumentation used to diagnose non-palpable breast lesions

Cancer Therapy - Researchers' data advance Cancer Therapy research

Breast Cancer - Breast ductal lavage samples bear biomarkers

Breast Cancer - Case of nodular fascitis of the breast presented

Breast Cancer - Conjugated linoleic acid may limit VEGF-A expression in breast tumors

Breast Cancer - Data show survival benefit of Arimidex over tamoxifin in early breast cancer

Breast Cancer - Estrogen and high LET-radiation induced breast cancer tumorigenesis

Breast Cancer - Expression of Com-1 correlated with prognosis of breast cancer patients

Cancer Therapy - Studies add new findings to Cancer Therapy body of knowledge

Breast Cancer - Expression of androgens and androgen receptors linked to risk of breast cancer

Breast Cancer - Femara shows survival improvement in women with hormone-sensitive early breast cancer

Breast Cancer - Nanotechnology shows promise in finding and treating breast tumors

Breast Cancer - Novel group of genes regulates drug susceptibility in breast cancer cells

Breast Cancer - Oxidative stress implicated in breast cancer

Breast Cancer - Phase II data on potential new therapy for the treatment of breast cancer announced

Cancer Therapy - Studies advance knowledge in Cancer Therapy research

Breast Cancer - Polymorphisms of the BRCA2 gene associated with breast cancer

Breast Cancer - Reduced dose capecitabine deemed effective treatment in metastatic breast cancer

Breast Cancer - Self-help online breast cancer bulletin boards evaluated

Breast Cancer - Sentinel lymph node biopsy reduces incidence of lymphedema and erysipelas

Breast Cancer - Studies evaluate impact of switching on survival in adjuvant treatment of early breast cancer

Breast Cancer - Study characterized antibodies involved in malignancy-induced autoimmunity to MUC1

Cancer Vaccines - Reports add new data to Cancer Vaccines research

Breast Cancer - Study demonstrates correlation between biomarker reactivity and breast cancer recurrence risk

Breast Cancer - Study shows TC chemotherapy superior to AC in disease-free survival among breast cancer patients

Breast Cancer - Study shows positive results for dose-dense combination therapy for early-stage breast cancer

Breast Cancer - Symposium highlights that genetic differences may determine breast cancer risk

Breast Cancer - Weekly administration of docetaxel and paclitaxel used to treat breast cancer

Breast Cancer - [F-18]FLT-positron emission tomography used to quantify cellular proliferation

Cancer Vaccines - Reports advance knowledge in Cancer Vaccines research

Breast Cancer Diagnostics - Fine needle aspiration cytology used as adjunct to core biopsy in breast cancer diagnosis

Breast Cancer Risk Factors - Mammographic density in postmenopausal women is independent of circulating sex hormones

Breast Cancer Risk Factors - Physical activity is inversely related to breast cancer risk

Breast Cancer Screening - Anxiety for women recalled for second mammography is similar regardless of family history

Breast Cancer Screening - Insurance status among African-American women is strongest predictor for mammography use

Breast Cancer Screening - Optical transillumination spectroscopy is a good predictor of tissue density

Chemotherapy - Researchers provide details of new studies and findings in the area of chemotherapy

Breast Cancer Survival - Long-term breast cancer survivors benefit from uncertainty management intervention

Breast Cancer Therapy - Report describes side effects observed with cancer risk reduction for tamoxifen

Breast Cancer Vaccine - Immunization with mucin 1 and its coding DNA had anti-tumor effect

Business & Finance - Research note issued on Callisto Pharmaceuticals

Business & Finance - orBec maker receives extension to comply with AMEX listing standards

Cancer Diagnostics - Efficacy of EUS-guided fine needle tissue acquisition to evaluate solid masses assessed

Chemotherapy - Researchers publish new studies and findings in the area of chemotherapy

Cancer Diagnostics - Methods for enumerating circulating tumor cells in carcinoma patients compared

Cancer Diagnostics - Telomerase activity detected by real-time TRAP assay in body fluids

Cancer Gene Research - Arrayed primer extension detects breast and ovarian carcinoma mutants

Cancer Gene Therapy - Combinatorial antiangiogenic gene therapy regresses tumors in glioblastoma

Cancer Gene Therapy - E2F-1 gene therapy up-regulates PKR and inhibits growth of leiomyosarcoma

Cancer Gene Therapy - PKR-induced mammalian cell death tested in an antisense cellular screening assay

Diagnostics - Research in diagnostics provides new insights

Cancer Gene Therapy - Tropism expanded in a human adenoviral vector with a chimeric fiber

Cancer Registries - Patient perspectives on research recruitment surveyed through cancer registries

Cancer Research - Phase III data show Aranesp increases and maintains patient hemoglobin levels

Cancer Risk Factors - Nonsignificant difference found for cancer risk factors when stratified by education level

Cancer Risk Factors - Researchers publish new studies and findings in the area of Cancer Risk Factors

Cancer Therapy - A PSP94-derived peptide PCK3145 inhibits MMP-9 secretion

Diagnostics - Researchers detail new studies and findings in the area of diagnostics

Cancer Therapy - Advances in radiotherapy show benefit for elderly patients with leukemia and non-Hodgkin lymphoma

Cancer Therapy - Affymax, partner present preclinical data for novel angiogenesis inhibitors

Cancer Therapy - Angiotensin II receptor blockers staunch prostate cancer proliferation

Cancer Therapy - Brain cancer treatment approved in Scotland but still not available to all in U.K.

Cancer Therapy - CTLA-4 provides a potential target for antitumor therapeutic intervention

Cancer Therapy - Chemotherapy and resection therapy clarified in anaplastic oligodendroglioma

Diagnostics - Researchers' data advance diagnostics research

Cancer Therapy - Data supports potential clinical utility of GRN163L in patients with multiple myeloma

Cancer Therapy - Drug-development company starts clinical trial with PHP in first-line extension

Cancer Therapy - Dual integrin antagonist elicits antiangiogenic activity

Cancer Therapy - Enzyme inhibitor limits radiation-induced tumor angiogenesis and invasion

Cancer Therapy - Extracellular matrix adherence linked to suppression of peritoneal implantation

Cancer Therapy - Findings in Cancer Therapy provide new insights

Oncology - Research add new data to oncology body of knowledge

Cancer Therapy - Glioma cell growth inhibited by siRNA targeting of growth factor

Cancer Therapy - HGS-ETR2 is well tolerated in patients with advanced solid tumors

Cancer Therapy - Hematologic safety and tolerability of topotecan investigated

Cancer Therapy - Human acute lymphoblastic leukemia cells produce human pregnancy hormone hCG

Cancer Therapy - Mechanism of an anticancer lysophospholipid described

Cancer Therapy - Medical technology company receives additional U.S. patent for cancer treatment system

Oncology - Researchers provide details of new studies and findings in the area of oncology

Cancer Therapy - Nonsteroidal anti-inflammatory drugs marked for development into anticancer agents

Cancer Therapy - O-6-benzylguanine and temozolomide used to treat pediatric patients with solid tumors

Cancer Therapy - Optimum management of patients with low-grade gliomas investigated

Cancer Therapy - Oral temozolomide used for heavily pre-treated brain metastases

Cancer Therapy - Phase II study of oregovomab for recurrent ovarian cancer indicates further study is warranted

Oncology - Researchers publish new studies and findings in the area of oncology

Cancer Therapy - Positive PXD101 phase I results presented at the American Society of Hematology

Cancer Therapy - Primary tumor of pancreatic cancer measured in chemotherapy trials

Cancer Therapy - Quadramet/ bortezomib combo demonstrates broad anticancer activity in preclinical study

Cancer Therapy - Radioiodine tracks the pharmacokinetics of angiostatin

Oncology - Studies add new findings to oncology body of knowledge

Cancer Therapy - Results reported of Phase II interleukin-2, granulocyte-macrophage colony-stimulating study

Cancer Therapy - Use of agarose capsules chemotherapeutically targets tumors

Cancer Vaccine -  Psidium guajava extracts exert antitumor effect

Oncology - Studies advance knowledge in oncology research

Cancer Vaccine - Adenovirus-mediated transfer of FRNK augments drug-induced cytotoxicity

Cancer Vaccine - Herpes simplex virus type-1 amplicons linked to vaccine generation in lymphoblastic leukemia

Cancer Vaccine - Knowledge of metastases and their microenvironments aids therapy design

Cancer Vaccine - Monoclonal antibodies for MK-1/Ep-CAM have been prepared

Cancer Vaccine - Neutralizing intrabodies against Etk kinase impair cellular transformation

Cancer Vaccine - Study identified amino acids of Sindbis virus protein involved in targeting tumor metastases

Prostate Cancer - Researchers describe findings in Prostate Cancer studies

Cancer Vaccine - Tumor cell-pulsed dendritic cells and activated lymphocytes prolong survival

Cancer Vaccines - New data illuminates research in Cancer Vaccines

Carcinogenesis - Colonic chicken-skin mucosa in children with polyps is not a preneoplastic lesion

Cardiac Papillary Fibroelastoma - Surgery used to treat cardiac papillary fibroelastoma

Cell Biology - Cell migration is induced by nucleotide receptor interaction with integrins

Cervical Cancer - Findings in Cervical Cancer provide new insights

Cervical Cancer Screening - Abnormal results in combination tests allow for improved prediction of cancer risk

Chemotherapy - New data illuminates research in chemotherapy

Chemotherapy - Potential signal for arrhythmias and cardiac arrest are found with dolasetron

Chemotherapy - Squamous and nonsquamous cancers respond alike to platinum-based combination chemotherapy

Cholangiocarcinoma - Genetic and environmental determinants of risk for cholangiocarcinoma examined

Choroidal Melanoma - Progression of choroidal melanocytes described

Chronic Lymphocytic Leukemia - Drug for lymphocytic leukemia shown to be generally well tolerated and biologically active

Chronic Lymphocytic Leukemia - Phase II talabostat plus rituximab trial exceeds targeted 20% response rate in CLL patients

Clinical Trials - Integrin antagonist MEDI-522 may impede tumor angiogenesis

Collaborations - Alliance formed to identify genes associated with cardiovascular disease, diabetes and cancer

Collaborations - Clinical trial alliance focuses on reducing the side effects of chemotherapy drugs

Collaborations - Partnership combines human antibody therapeutic pipelines

Colon Cancer - Anemia deemed poor predictor of right-sided colon cancers

Colon Cancer - Galectin-3 modulates MUC2 mucin expression in human colon cancer cells

Colon Cancer - Immunity induced by injection of dendritic cells expressing interleukin-15

Colon Cancer - Retinol inhibited growth of colon cancer cells

Colon Cancer - Risk of colorectal adenocarcinoma heightened in patients treated for appendiceal adenocarcinoid

Colon Cancer Vaccine - Epitope-specific immunization inhibits epidermal growth factor receptor signaling

Colorectal Cancer - Better outcomes achieved with laparoscopic than open colectomies

Colorectal Cancer - Colorectal cancer incidence among female textile workers in Shanghai trended

Colorectal Cancer - DCs fused with colorectal cancer cells induce immunity against autologous tumor cells

Colorectal Cancer - Guidelines for follow-up after polypectomy based on size, location, and number of polyps

Colorectal Cancer - JC virus DNA sequences detected in colorectal cancers in Japan

Colorectal Cancer - Major hepatectomy for colorectal cancer metastasis improved survival in elderly

Colorectal Cancer - Prognostic and predictive significance of the p53 mutation assessed

Colorectal Cancer - Study finds strong link between diabetes and increased risk of colon and rectal cancer

Colorectal Cancer - Surgery promoted implantation of disseminated tumor cells

Colorectal Cancer - Synchronous liver resection and cryotherapy effective for metastases

Colorectal Cancer - Two new clinical sites added for colorectal drug trial in Israel

Colorectal Cancer Screening - Quality improvement program targeting provider organizations fails to increase screening rates

Complementary & Alternative Medicine - Herbal agent overwhelms glioma proliferation

DNA Damage - Jun activation domain-binding protein required for mitotic checkpoint activation

Dermatofibrosarcoma - Outcome of patients with primary or recurrent dermatofibrosarcoma protuberans analyzed

Diagnostics - Detection of second primary cancer improved using F-18-FDG PET/CT

Diagnostics - Diagnostics company announces gene-based assay to ID cancers of unknown primary origin

Diagnostics - Diagnostics company presents data on soon-to-be introduced assay for hematologic diseases

Diagnostics - Expression pattern of beta-catenin used to diagnose mesothelial lesions

Diagnostics - Molecular end point can be a safe and effective tool for clinical decision making

Diagnostics - New findings in the area of diagnostics described

Diagnostics - Preoperative tumor staging improved with fluorescence-based staging laparoscopy

Diagnostics - Rapid assay detects fibroblast growth factor receptor 3 mutations in bladder cancer and urine

Diagnostics - Rights acquired to lung cancer screening test from University of Kentucky

Diet & Nutrition - Vitamin D is important for prevention of bone, heart, and autoimmune diseases

Disease Associations - Colorectal polyps detected in patients with sporadic adenomas or adenocarcinomas

Disease Associations - Greater awareness needed for adverse impact of anemia on cancer patients

Disease Associations - Risk factors leading to hypercholesterolemia and colorectal cancer studied

Drug Development - 1,4-DHP derivative promotes DNA repair in cultured human cells

Drug Development - AMN107 can produce dramatic benefits in some forms of leukemia resistant to Gleevec

Drug Development - Farnesyltransferase inhibitor ABT-100 abates angiogenesis

Drug Development - GSK selects development candidate directed to second mitotic kinesin target

Drug Development - N-acylethanolamines and other antimitotic agents evaluated as possible inductors of apoptosis

Drug Development - National Cooperative Drug Discovery Group names pharma company as corporate partner

Drug Development - Oral toll-like receptor ligand chosen as next drug development candidate for cancer

Drug Development - Phase I trial for Imprime PGGTM cancer therapy initiated

Drug Development - Plasminogen kringle 5 deletion mutant may control pathological angiogenesis

Drug Development - Proteasome inhibitors evaluated in lymphoid malignancies

Drug Development - Synthesis and biological evaluation of polyhydroxycurcuminoids described

Drug Development - Synthetic vascular endothelial growth factor receptor binding antagonist may fight cancer

Drug Devleopment - Integrin-linked kinase blockade targets signals linked to glioblastoma progression

Drug Resistance - Data advance knowledge in Drug Resistance research

Drug Resistance - Oral VEGF receptor inhibitor YM-231146 beats paclitaxel resistant tumors

End-of-Life Issues - Women and elderly cancer patients were less likely to receive formal terminal diagnosis

Endocrinology - Researchers' data advance endocrinology research

Endometrial Cancer - Interindividual variation in XPA and XPC influences the risk of endometrial cancer

Endometrial Cancer - Prevalence of hysterectomy among blacks may account for lower endometrial cancer rates

Endometrial Cancer Screening - Gadolinium-enhanced FMPSGR sequences improve MRI evaluation of myometrial invasion

Epidermoid Tumors - Treatment planning of epidermoid tumor aided by FLAIR and DWI