Cancer Weekly

Brain Cancer - Contrast-enhanced MR imaging at 3.0 T yielded higher CNR than at 1.5 T

Breast Cancer - Human embryonic SC genes OCT4/NANOG/STELLAR/GDF3 expressed in seminoma and breast cancer

Cancer Inhibition - 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibited cancer cells

Fitness & Wellness - QoL was lower in non-Hodgkin lymphoma survivors not meeting health exercise guidelines

Melanoma - 3D MRI delineated tumor shape of ocular melanoma

Acoustic Neuroma - Image distortion of neuromas treated with gamma knife radiosurgery examined

Antimicrobials - Bacteremia due to Pseudomonas aeruginosa analyzed

Apoptosis - Glycyrrhetinic acid induced apoptosis in human hepatocellular carcinoma

Apoptosis - Lysosomes and endoplasmic reticulum nominated as targets for anticancer therapy

Apoptosis - Natural and synthetic retinoids induced different apoptotic pathways in lymphoma

Apoptosis - Recent findings illuminate research in apoptosis

Cancer Therapy - New findings in the area of Cancer Therapy detailed

Apoptosis - Researchers identify protein that determines life and death of cells during development

Bioterrorism - Callisto's program to develop biowarfare vaccines featured in audio interview

Bladder Cancer - ALA fluorescence assisted transurethral resection conferred long-term benefits in bladder cancer

Bladder Cancer - Flavopiridol induced growth inhibition and apoptosis in bladder cancer cells

Bladder Cancer - Quality of life after cystectomy and urinary diversion assessed

Brain Cancer - Diffusion tensor tractography used for neurosurgical planning

Cancer Therapy - Recent findings in Cancer Therapy described

Brain Metastases - Current treatment approaches for brain metastases surgery discussed

Brain Metastases - Strategies in whole-brain radiation therapy for brain metastases discussed

Brain Metastases - Use of chemotherapy to treat brain metastases examined

Brain Tumors - Depression found to be associated with brain tumors

Breast Cancer - Artificial light at night stimulates growth of breast tumors in laboratory mice

Breast Cancer - Beta integrins are inessential for murine mammary tumor growth and progression

Cancer Therapy - Research in Cancer Therapy provides new insights

Breast Cancer - Common oncoproteins are not linked to angiogenic cytokine in ductal carcinoma in situ

Breast Cancer - Conflictive families manifested highest level of depression and anxiety

Breast Cancer - Course of emotional adjustment after radiation therapy for breast cancer tracked

Breast Cancer - Different radiotherapy treatment-planning systems for breast cancer compared

Breast Cancer - Double staining of MIB-1 and AgNORs used to predict lymph node metastasis

Breast Cancer - Gemcitabine and vinorelbine used to treat metastatic breast cancer

Cancer Therapy - Researchers publish new studies and findings in the area of Cancer Therapy

Breast Cancer - HRT no help for hot flashes in women taking tamoxifen, researcher says

Breast Cancer - Interim efficacy, updated safety analyses from Phase III breast cancer study presented

Breast Cancer - N-sulfonylpyrimidine derivatives exhibited antitumor activity in breast cancer

Breast Cancer - Needle-localized open breast biopsy used to diagnose breast lesions

Breast Cancer - New findings in the area of Breast Cancer detailed

Breast Cancer - Oral ibandronate deemed cost-effective treatment for metastatic bone disease

Cancer Therapy - Researchers report details of new studies and findings in the area of Cancer Therapy

Breast Cancer - Prediction model being developed to identify risk of developing anemia

Breast Cancer - p75 neurotrophin receptor found to be a marker of breast myoepithelial cells

Breast Cancer Mortality - Reasons for increased mortality among highly educated women differs depending on parity

Breast Cancer Risk Factor - Breast cancer risk and coffee consumption may not be related among BRCA carriers

Breast Cancer Risk Factor - Father's age at birth is associated with increased breast cancer risk in female offspring

Breast Cancer Risk Factor - Risk of breast cancer was not found to be associated with dietary patterns

Cancer Therapy - Researchers' findings advance Cancer Therapy research

Breast Cancer Risk Factor - Soliciting family medical history does not increase cancer worry in patients

Breast Cancer Risk Factor - Type of BRCA mutation influences breast cancer risk in multiparous carriers

Breast Cancer Risk Factor - Women with history of ovarian cysts show decreased risk of breast cancer

Breast Cancer Therapy - Expression changes in multiple genes result from estradiol-deprived breast cancer cells

Breast Cancer Therapy - Few differences seen in therapy for pregnant vs. non-pregnant breast cancer patients

Breast Cancer Therapy - Little improvement seen in breast cancer processes of care among vulnerable populations

Cancer Therapy - Studies describe new findings in Cancer Therapy research

Breast Cancer Therapy - Study contradicts reports of problems with cognitive functioning linked to chemotherapy

Breast Reconstruction Surgery - Immediate breast reconstruction postmastectomy is not frequently chosen by patients

Business & Finance - Tumor treatment-focused company completes second closing

Business Update - Clofarabine scheduled for Oral Explanation

Business Update - Wyeth signs agreement related to treatments for metabolic and liver diseases

Cancer Gene Therapy - ASH1 gene is a specific therapeutic target for lung cancers

Cancer Vaccines - Research add new data to Cancer Vaccines body of knowledge

Cancer Gene Therapy - Akt blocks breast cancer cell motility and invasion

Cancer Gene Therapy - Expression of migration stimulating factor is uniquely controlled

Cancer Gene Therapy - Integration of the Sleeping Beauty transposon replicates liver tumor development

Cancer Mortality - Reduction of cancer mortality should target behavioral and environmental interventions

Cancer Prevention - Prevention of adenocarcinoma of distal esophagus and proximal stomach discussed

Cancer Research - Pharma company advances clinical development programs for R788 and R763

Cancer Vaccines - Studies advance knowledge in Cancer Vaccines research

Cancer Research - Study shows limitations in current pathology methodology used in protein biomarker studies

Cancer Risk Factors - Exposure to drinking-water nitrate as a cancer risk factor evaluated

Cancer Survivors - Work experiences studied among diverse group of cancer survivors

Cancer Therapy - A full-length liposome complex suppresses growth of human colon cancer

Cancer Therapy - Adeno-associated virus transduction efficiency improved in human cancer cells

Cancer Therapy - Antibody therapy promising for pediatric neuroblastoma

Cervical Cancer - Researchers detail new studies and findings in the area of Cervical Cancer

Cancer Therapy - Bcl-2 and bax expression appear to be associated with a risk factor in oral cancer progression

Cancer Therapy - Broad cytotoxic activity of titanium dichloride observed

Cancer Therapy - Cancer treatment choices are affected by whether outcomes achieved actively or passively

Cancer Therapy - Chemotherapy consolidation with Zevalin may provide therapeutic benefit for MCL patients

Cancer Therapy - Codeinone induced apoptosis in human cancer cell lines

Cancer Therapy - Conjugated linoleic acid isomers inhibited growth of human cancer cell lines

Diagnostics - Recent findings in diagnostics provide new insights

Cancer Therapy - Dendritic cell therapy arrests carbonic anhydrase II activity in tumor vessels

Cancer Therapy - Doxazosin showed growth inhibitory effect on prostate and bladder cancer cells

Cancer Therapy - Early chemotherapy considered for high-risk localized prostate cancer

Cancer Therapy - Findings advance knowledge in Cancer Therapy research

Cancer Therapy - GVAX vaccine for chronic myelogenous leukemia reduced persistent disease in some patients

Cancer Therapy - HuMax-CD20 induces rapid responses in relapsed chronic lymphocytic leukemia patients

Diagnostics - Research add new data to diagnostics body of knowledge

Cancer Therapy - Humanized anti-CD20 antibody appears safe and active in non-Hodgkin lymphoma

Cancer Therapy - Impaired retinoic acid signal leads to receptor silencing and resistance

Cancer Therapy - Investigational therapy enhances breast cancer treatments, preclinical studies show

Cancer Therapy - Israeli researchers discover mechanisms causing cancer cell resistance to chemo

Cancer Therapy - Monophenolic compounds induce minimal apoptosis in murine leukemia cells

Diagnostics - Researchers' findings advance diagnostics research

Cancer Therapy - Oral antiangiogenic chemotherapy regimens deter cancer progression in pediatric patients

Cancer Therapy - Patients achieve complete hematological response in phase II trial of Ceflatonin

Cancer Therapy - Pivotal trials initiated for Zensana for chemotherapy-induced nausea and vomiting

Cancer Therapy - Positive data presented on anticancer drug AS1409

Diagnostics - Studies add new findings to diagnostics body of knowledge

Cancer Therapy - SIRT1 is a target for killing epithelial cancer cells

Cancer Therapy - U.S. FDA grants clearance for eye cancer proton therapy treatment planning tool

Oncology - Recent findings illuminate research in oncology

Cancer Vaccines - Recent studies add new data to Cancer Vaccines research

Cervical Cancer - Aberrant cell cycle regulation may aid in progression and development of cervical cancer

Cervical Cancer - CDC27 protein involved in radiation response in squamous cell cervix carcinoma

Cervical Cancer - CT and MR imaging were moderately sensitive in detecting nodal metastases

Oncology - Researchers report details of new studies and findings in the area of oncology

Cervical Cancer - Higher HPV DNA copy number corresponds to increased risk of cervical adenocarcinoma

Cervical Cancer - Pre-exenterative chemotherapy used to treat patients with cervical cancer

Cervical Cancer - Research in Cervical Cancer provides new insights

Cervical Cancer Risk Factors - Injectable hormonal contraceptives raise risk of cervical precancer in HPV-positive women

Chemotherapy - Metopimazine deemed effective in preventing delayed nausea and emesis in chemotherapy

Oncology - Researchers' work adds to oncology body of knowledge

Chemotherapy - Mini-FOLFOX-4 safe and effective as first-line palliative chemotherapy in elderly patients

Chemotherapy - Researchers report details of new studies and findings in the area of chemotherapy

Chronic Myeloid Leukemia - Imatinib mesylate enhances chronic myeloid leukemia stem cell elimination

Clear Cell Chondrosarcoma - Inadequate surgical resection of clear cell chondrosarcoma leads to recurrence

Clear Cell Sarcoma - Dual-color, break-apart FISH used to diagnose clear cell sarcoma

Clinical Trials - Aurora kinase inhibitor impacts relevant biomarker in phase I cancer study

Radiotherapy - New findings in the area of radiotherapy described

Clinical Trials - Enrollment complete for phase II trial of drug for superficial basal cell carcinoma

Clinical Trials - Interim results of phase I/II trial for anti-cancer drug announced

Clinical Trials - Offering to help advance actinic keratosis trials program

Clinical Trials - Phase II trial of heat shock protein inhibitor for metastatic breast cancer initiated

Clinical Trials - Positive phase I/2 data of immunotherapy product in cutaneous lymphoma reported

Clinical Trials - Small molecule drug treatment demonstrates significant responses in phase II MDS trial

Stem Cell Transplantation - Studies add new findings to Stem Cell Transplantation body of knowledge

Clinical Trials - Trial to evaluate satraplatin plus paclitaxel in advanced non-small cell lung cancer

Clinical Trials - Velcade trial shows positive results in variety of lymphomas

Clinical Trials - XL999, a spectrum selective kinase inhibitor, moves into phase II program

Collaborations - Collaboration, partnership agreements bring medical isotope testing to Idaho

Collaborations - Natco Pharma Limited to collaborate on development and supply of two oral anti-nausea drugs

Colorectal Cancer - Computed tomographic colonography used to detect colorectal polyps and cancer

Colorectal Cancer - Extended surgery and postoperative interstitial IMBT deemed feasible treatment

Colorectal Cancer - Genetic changes were associated with aggressive behavior of colorectal adenocarcinoma

Colorectal Cancer - Germline mutations of MYH gene differed between Japanese and Caucasians

Colorectal Cancer - Increasing incidence of colorectal cancer detected in Asia

Colorectal Cancer - Prognostic score based on total number of colorectal liver metastases proposed

Colorectal Cancer - Psychosocial intervention did not affect well-being of Danish colorectal cancer patients

Colorectal Cancer - RASSF1A hypermethylation and KRAS/BRAF mutations detected in colorectal cancer

Complementary & Alternative Medicine - Antitumor activity of Pulsatilla koreana saponins analyzed

Complementary & Alternative Medicine - Enhanced professional herb guide accredited through 2008

DNA Research - Data from DNA bank show genetic variations that may indicate myeloma risk factors

DNA Research - Optimized TRAP assay remains nonspecific for telomerase inhibitors

DNA Research - Synthesized pentacyclic acridinium salts destabilize telomeric integrity

Dermatology - Biomarkers may trace dormant benign melanocytic nevi to malignant melanomas

Dermatology - Endogenous nitric oxide triggers vascular endothelial growth factor-induced melanoma growth

Diagnostics - Antiangiogenic therapy and chemotherapy have distinct effects on radiotracer accumulation

Diagnostics - Cancer screening company changes name to CytoCorp

Diagnostics - Changes in p120 catenin are a sign of colon cancer progression

Diagnostics - Diagnostics company announces a new installation of the MaxLife Center for Men in Florida

Diagnostics - Diagnostics products company submits regulatory information to U.S. FDA for Lymphoseek

Diagnostics - Findings in diagnostics provide new insights

Diagnostics - Sainte-Anne Hospital classification of oligodendrogliomas reappraised

Diet & Nutrition - Antioxidants' mechanism in disease prevention must be defined

Diet & Nutrition - Diet might influence probability of tumor formation

Disease Associations - Case of testicular tumor related to Down syndrome

Disease Associations - EBV+ CNS lymphoma resolves with appearance of CSF EBV-specific T cells

Disease Associations - Fever of unknown origin associated with cancer

Disease Associations - Hashimoto thyroiditis might be associated with papillary thyroid carcinoma

Disease Associations - Medullary thyroid carcinoma risk increases in Hirschsprung disease

Drug Delivery - Recent studies add new data to Drug Delivery research

Drug Development - A new thrombogen blocks tumor growth and angiogenesis

Drug Development - Antibodies win European and U.S. orphan drug status

Drug Development - Anticancer drug Nexavar granted U.S. approval

Drug Development - CEO reviews development plan for cancer therapeutics and diagnostic product business

Drug Development - Fodosine studies indicate potential benefits in treating relapsed, refractory T-cell leukemia