Colorectal Cancer
Germline mutations of MYH gene differed between Japanese and Caucasians
Published in Cancer Weekly, January 17th, 2006
"Germline mutations of the MYH gene have been revealed to associate with the recessive inheritance of multiple colorectal adenomas in Caucasian population. However, MYH mutations in Japanese patients have not yet been clarified," scientists writing in the journal Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis reported.
"In an assessment of MYH mutations, we examined 35 Japanese patients with multiple colorectal adenomas who had neither dominant inheritance of colorectal tumors, nor germline APC mutations. One patient had a homozygous biallelic...
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Source: Cancer Weekly (2006-01-17)
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