Endometrial Cancer
High skp2 expression prognosticated endometrial endometrioid adenocarcinoma
Published in Cancer Weekly, January 17th, 2006
"Skp2 interacts with the degradation of cyclin-dependent kinase inhibitor p27. This study aimed to investigate the correlation of skp2 expression with the expression of p27 and other cell cycle regulators, and clinicopathological parameters in endometrial endometrioid adenocarcinoma. Tissue samples of 136 endometrioid adenocarcinomas, in addition to 20 endometrial hyperplasias and 20 normal endometria, were immunohistochemically stained for skp2," scientists in Japan reported.
"The expression was represented as a labeling index (LI), which indicates...
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Source: Cancer Weekly (2006-01-17)
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