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Pancreatic Cancer

Expression of RET could be used to prognosticate pancreatic cancer

Published in Cancer Weekly, January 17th, 2006

Expression of RET could be used as a prognostic marker in pancreatic cancer tissues.

According to recent research from Japan, "The glial cell line-derived neurotrophic factor (GDNF) is a member of neurotrophic polypeptide family, which promotes survival and rescue of various neural cells in the central and peripheral nerve systems. We previously reported that GDNF promotes tumor cell invasion in pancreatic cancer cell lines."

"The purpose of this study was to investigate GDNF family expression and the status of related receptors in actual cancer tissues, and assess correlations with clinicopathologic behavior. Immunohistochemical assessment of GDNF,...

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