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Cancer Weekly

Susan Hasty, Publisher

Table of Contents . . . January 24th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cancer Weekly | Other Publications

Cancer Therapy - Maximum tolerated dose of continuous mitomycin-C infusion determined

Cancer Therapy - Paclitaxel decreased uptake of gemcitabine in human leukemia cells

Drug Development - Organometallic compounds induce cytostatic and cytotoxic effects on cancer cells

Drug Development - PBT-3 caused long-term growth inhibition of K562 solid tumors in vivo

Prostate Cancer - Presence of apoptotic bodies could be used in diagnosis of prostate cancer

Actinic Keratoses - Diclofenac in 2.5% hyaluronan gel is effective for actinic keratoses

Acute Myeloid Leukemia - MRP3, BCRR and P-glycoprotein activities can prognosticate leukemia

Acute Myeloid Leukemia - New findings in Acute Myeloid Leukemia described

Acute Myeloid Leukemia - Pathogenic mechanism differed in cytogenetic subgroups of acute myeloid leukemia

Adenovirus Vaccine - Review focused on inactivating antiviral responses during adenovirus infection

Adipogenesis - Stromelysin-3 is a potent negative regulator of adipogenesis

Adrenocortical Cancer - Tumor stage used as prognostic factor for children with adrenocortical carcinoma

Apoptosis - 1-(3,4-dimethoxyphenyl)-3,5-dodecenedione induced apoptosis in leukemia

Apoptosis - A better understanding of the pathways governing apoptosis may yield new targets for therapy

Apoptosis - Abrogation of hsp70 induction increased antileukemia activity of 17-AAG

Apoptosis - Artemisinin and sodium butyrate showed cytotoxic effect on human cancer cells

Apoptosis - Inhibited nuclear translocation overcomes apoptosis signaling defects in B-cell malignancies

Apoptosis - Inhibition of apoptosis triggers hepatocarcinogenesis

Apoptosis - LAQ824 and roscovitine induced apoptosis in human leukemia cells

Apoptosis - Reports add new data to apoptosis research

Apoptosis - Researchers describe findings in apoptosis studies

Apoptosis - Researchers provide details of new studies and findings in the area of apoptosis

Apoptosis - Tumor suppressive effects of tocotrienol showed potential

Avian Influenza - Chinese corporation contracts for diagnostic test kit for avian influenza

Barrett Esophagus - Continued use of esophagectomy as treatment for high-grade dysplasia supported

Biliary Stenosis - K-ras mutation assays are useful in assessing extrahepatic biliary stenoses

Bladder Cancer - Urine ThinPrep specimens reveal disease stage in patients with bladder cancer

Bladder Cancer - Uroplakin II proposed as a marker of nodal metastases from bladder cancer

Bladder Tumors - Bladder transitional cell tumors 9q, 11p and 14q LOH were under-represented

Bone Cancer - Phase 1 preliminary findings in multiple myeloma study presented at hematology meeting

Bone Tumors - Transarticular invasion of bone tumors across the sacroiliac joint discussed

Brain Cancer - Ability of MET-PET to diagnose dysembryoplastic neuroepithelial tumors assessed

Brain Cancer - Radiosurgery for metastatic brain cancer discussed

Brain Cancer - Reports describe recent advances in Brain Cancer research

Brain Cancer - Surgery for primary brain tumors indicated quality of U.S. academic training

Breast Cancer - Adjuvant systemic therapy used to treat male breast carcinoma

Breast Cancer - Alpha6beta4 integrin depends on VEGF to maintain malignant breast tumor growth

Breast Cancer - Angiogenic induction may be a key feature of hormone-dependent breast cancer

Breast Cancer - Breast cancer resistance protein may not be primarily involved in multiple myeloma

Breast Cancer - Cancer diagnostics company highlights method of detecting nuclear matrix protein complex

Breast Cancer - Cause-specific survival of patients with inflammatory breast cancer trended

Breast Cancer - Cell stress protein linked to aggressive breast cancer disease

Breast Cancer - Effectiveness of permanent radiation seed implants being studied

Breast Cancer - Faults in newly discovered breast stem cells may lead to tumors

Breast Cancer - Femara receives U.S. approval for new treatment indication

Breast Cancer - Findings in Breast Cancer provide new insights

Breast Cancer - Letrozole as post-operative breast cancer therapy reduces recurrence, large study shows

Breast Cancer - Lobular breast cancer metastasized to the colon

Breast Cancer - New findings in Breast Cancer described

Breast Cancer - New research in the area of Breast Cancer detailed

Breast Cancer - Optimal adjuvant radiation therapy associated with improved survival

Breast Cancer - Overexpressed Twist alters angiogenesis and chromosomal stability in breast tumors

Breast Cancer - Pitfalls of using FDG-PET for the diagnosis of bone metastases identified

Breast Cancer - RNA interference in breast cancer cells alters differentiation and proliferation

Breast Cancer - Research affirms connection between surgical expertise and outcome

Breast Cancer - Studies describe new findings in Breast Cancer research

Breast Cancer - The MCT-1 oncogene promotes tumor angiogenesis and blocks apoptosis

Breast Cancer - Touch prep analysis advised in patients at high risk of nodal metastasis

Breast Cancer - Use of light therapy for breast-cancer-related fatigue evaluated

Breast Cancer - Use of sentinel node biopsy for breast cancer staging validated

Breast Cancer Frequency - Higher rate of cancer incidence in urban hospitals may be factor of increased detection

Breast Cancer Prevention - Exercise-induced melatonin did not have preventive effect against breast cancer

Breast Cancer Prevention - Prophylactic endocrine treatment is not recommended outside clinical trial setting

Breast Cancer Risk Factors - Polymorphisms in MGMT modulate inverse association of antioxidants and cancer risk

Breast Cancer Screening - Combined mammography, ultrasound, and MRI increases sensitivity for detecting cancer risk

Breast Cancer Screening - Magnetic resonance imaging is useful in detecting occult cancer after negative mammograms

Breast Cancer Survival - Benefits of longer tamoxifen therapy were seen in younger estrogen receptor-positive women vs. older women

Breast Cancer Survival - Employment status of cancer survivors is not associated with adjuvant therapy

Breast Cancer Therapy - Mental health plays strong role in chemotherapy-related fatigue in breast cancer patients

Breast Cancer Therapy - Residual disease is associated with skin flap thickness after skin-sparing mastectomies

Breast Cancer Therapy - Time to progression may be valuable surrogate marker in predicting breast cancer survival

Business & Finance - Previously announced sale of myoblast cell therapy program complete

Business Update - Medical technology company reports marketing progress of microendoscope for breast cancer

Cancer Cells - Three-dimensional culture of melanoma cells impairs their immunorecognition

Cancer Epidemiology - ErbB2 mutations are rare in Japanese patients with lung cancer

Cancer Gene Therapy - Angiogenesis and tumor growth inhibited in pancreatic adenocarcinoma

Cancer Immunotherapy - Antibody-based drugs may be more effective when combined with IL-2 or IL-12

Cancer Research - Advances reported in development of oncolytic viruses for cancer treatment

Cancer Research - Little known DNA repair enzyme may be a tumor suppressor gene

Cancer Research - Researchers curb activity of "watchdog" protein that slows spread of genetically predisposed cancer

Cancer Research - Results of in vitro bone marrow cancer cell study show gene technology effective

Cancer Research - Site and stage are important prognostic factors of malignant vascular tumors

Cancer Research - Study examined metabolic deviations related to weight loss during chemoirradiation

Cancer Research - U.S. DOD awards $1.5 million in research funding to Nebraska cancer center

Cancer Risk Factors - Notification of genetic test results did not adversely affect psychologic outcomes

Cancer Risk Factors - Shanghai study broadens examination of cancer etiologies across wider spectrum

Cancer Risk Factors - Weight change over adult life may not adversely affect cancer incidence in women

Cancer Support Groups - Motives for patients to join cancer associations surveyed

Cancer Therapy - Angiogenesis inhibitor ZD6474 helps control central nervous system tumors in mice

Cancer Therapy - Anticancer activity is displayed by light-induced ruthenium complexes

Cancer Therapy - Antisense/radiation therapy effectively treats nasopharyngeal cancer

Cancer Therapy - Breast cancer drugs may slow growth of lung cancer

Cancer Therapy - Cervical cancer vaccine candidate induced a higher immune response in young girls

Cancer Therapy - Concurrent growth factor inhibition and gemcitabine staunch pancreatic cancer growth

Cancer Therapy - Cytochrome modulation triggers apoptosis in tumor cells

Cancer Therapy - Data advance knowledge in Cancer Therapy research

Cancer Therapy - Findings describe new data in Cancer Therapy research

Cancer Therapy - Gefitinib with weekly epirubicin controls disease in patients with metastatic breast cancer

Cancer Therapy - Loss of the hSNF5 gene inactivates replicative senescence in rhabdoid tumors

Cancer Therapy - Melanoma differentiation-associated gene has diverse antitumor properties

Cancer Therapy - Method offers effective treatment for esophageal and cardia tumors

Cancer Therapy - Neoadjuvant chemotherapy used to treat liver metastases from colorectal cancer

Cancer Therapy - New platinum-based, anti-cancer agent overcomes drug resistance

Cancer Therapy - PPAR gamma-dependent effects of CLA on human glioblastoma cell line are investigated

Cancer Therapy - Pegamotecan exhibited antitumor activity in solid tumors and lymphomas

Cancer Therapy - Recent findings illuminate research in Cancer Therapy

Cancer Therapy - Reports add new data to Cancer Therapy research

Cancer Therapy - Reports describe recent advances in Cancer Therapy research

Cancer Therapy - Researchers describe findings in Cancer Therapy studies

Cancer Therapy - Researchers provide details of new studies and findings in the area of Cancer Therapy

Cancer Therapy - Soluble FLT-1 receptor thwarts vascular endothelial growth factor and angiogenesis

Cancer Therapy - Spectroscopic signatures for different forms of topotecan studied

Cancer Therapy - Study suggests a new prophylactic approach in the field of radioprotection of salivary glands

Cancer Therapy - Supplemental BLA submitted for Avastin in relapsed metastatic colorectal cancer

Cancer Vaccine - Density of carbohydrate epitopes on carrier affects IgG responses

Cancer Vaccine - Fibroblast activation protein shows promise as tumor antigen target

Cancer Vaccine - Soluble tumor-associated antigens exert preventive effect on tumorigenesis

Cancer Vaccines - Findings advance knowledge in Cancer Vaccines research

Cancer Vaccines - Recent findings illuminate research in Cancer Vaccines

Cancer Vaccines - Researchers' data advance Cancer Vaccines research

Cancer Vaccines - Studies add new findings to Cancer Vaccines body of knowledge

Carcinogenesis - UV-induced mutant p53 and skin tumors analyzed by mutation spectra and induction kinetics

Cardiovascular Disease - Surgical excision of papillary fibroelastoma should be valve-sparing

Cervical Cancer - 100% rapid rescreening deemed efficient in detecting cervical abnormalities

Cervical Cancer - eIF-4E expression associated with histopathologic grades in cervical neoplasia

Cervical Cancer Risk Factors - Presence of human papilloma virus increases cervical cancer risk among Mexican women

Cervical Cancer Screening - Reporting benign-appearing endometrial cells for women >40 years appears effective cutoff

Chemotherapy - Antiangiogenic chemotherapy in pediatric cancer patients deemed feasible

Chemotherapy - Chemotherapeutic cisplatin dosage can be reduced by ZD 1839

Chemotherapy - Vitamin C enhanced chemosensitization of esophageal cancer cells

Chronic Lymphocytic Leukemia - NDA filed for Genasense Injection

Cirrhosis - Neovascular characteristics distinguish hepatitis C-related liver lesions

Clear Cell Sarcoma - Up-regulation of neural markers detected in clear cell sarcoma of the kidney

Clinical Trials - Cancer cell-inhibiting drug shows significant activity in elderly leukemia patients

Clinical Trials - Enrollment complete in phase 3 trial of drug treatment of advanced ovarian cancer

Clinical Trials - Enrollment full in first phase 3 trial of oregovomab therapy in advanced ovarian cancer

Clinical Trials - Phase 3 clinical trial for oral cancer detection drug began with investigators' meeting

Clinical Trials - Promising interim phase 2 results in advanced stage malignant melanoma trial reported

Clinical Trials - Researcher presents argument for using new method in clinical trials

Clinical Trials - Results from Zadaxin proof-of-concept liver cancer trial indicate positive survival trend

Collaborations - Collaboration on vascular endothelial growth factor trap extended to include Japan

Collaborations - Pharma companies to collaborate on modeling of p38 kinase inhibitors

Colon Cancer - Abdominal wall abscess revealed unusual presentation of colon carcinoma

Colon Cancer - Impact of folate deficiency on colon cancer susceptibility assessed

Colon Cancer - Reports add new data to Colon Cancer research

Colorectal Cancer - Cholesterol-lowering drugs not associated with reduced disease risk

Colorectal Cancer - Colon cancer organization releases updated guidelines incorporating new technologies

Colorectal Cancer - Early chemotherapy in asymptomatic colorectal cancer did not improve survival

Colorectal Cancer - Persistence of ascitis predicted incomplete resectability of colorectal peritoneal carcinomatosis

Colorectal Cancer - Prospective study shows no association between dietary acrylamide and colorectal cancer

Colorectal Cancer - Protein expression used in prognosis of colorectal adenocarcinoma

Complementary & Alternative Medicine - Role(s) of bioactive food components in colon cancer prevention elucidated

Cutaneous Lymphoma - New WHO/EORTC classification of cutaneous lymphomas 2005 reviewed

DNA Vaccines - Studies advance knowledge in DNA Vaccines research

Diagnostics - Dogs may aid in early cancer detection

Diagnostics - Molecular imaging of apoptosis in cancer discussed

Diagnostics - New findings in the area of diagnostics detailed

Diagnostics - New monoclonal antibodies discern hypoxia regulatory factors in human tissues

Diagnostics - Peritoneal mesotheliomas and serous carcinomas diagnosed by immunohistochemistry

Diagnostics - Prior mammograms used in classification of benign and malignant masses

Diagnostics - Reports describe recent advances in diagnostics research

Diagnostics - Scanning electron microscopy helps quantify keratin networks in cancer cells

Diagnostics - Usefulness of cytopathologist's presence during CT-guided fine needle aspiration examined

Diet & Nutrition - Urinary phyto-estrogen concentrations in U.S. population are presented

Disease Associations - Associations between the kidney, renal cancers, and the eye reviewed

Disease Associations - Portal vein gas developed after chemoradiotherapy for esophageal carcinoma

Drug Development - 10f-TDAF identified as target for antineoplastic intervention

Drug Development - A new RNA aptamer targeting alphavbeta3 integrin hinders endothelial cell growth and survival

Drug Development - Cancer drug developer sums up pipeline progress

Drug Development - Favorable toxicity profile of tasidotin warrants further study of the drug

Drug Development - High response rates reported in use of single agent Treanda in non-Hodgkin lymphoma

Drug Development - Humanized anti-CD74 antibody has shown therapeutic activity in lymphoma and myeloma transplants

Drug Development - INDA filed with U.S. FDA for monoclonal antibody treatment of Hodgkin lymphoma

Drug Development - New drug application submitted to U.S. FDA for dasatinib

Drug Development - Pharmacogenomics of human ABC transporter ABCG2 described

Drug Development - Researchers describe findings in Drug Development studies

Drug Development - Swiss agency approves Erbituxfor for the treatment of head and neck cancer

Endocrinology - Research add new data to endocrinology body of knowledge

Endocrinology - Researchers' work adds to endocrinology body of knowledge

Endometrial Cancer - Circadian gene expression is disturbed in endometrial cancer

Environmental Health - Illinois lung association supports cleaner burning and alternative fuels

Epstein-Barr Virus - Proliferation of EBV-positive Burkitt lymphoma cells is inhibited by RNA interference

Esophageal Cancer - Link between adenocarcinoma and soft drinks debunked

Esophageal Cancer - Survival after surgery for esophageal cancer improved since 1987

Esophageal Cancer Vaccine - Drugs can promote effect of cancer/testis antigen-specific cancer vaccines

Facilities - DMI BioSciences is first tenant in new Colorado bioscience park

Fertility - Benefits and risks of ovarian tissue cryopreservation reviewed

Finance - Cancer diagnostics developer reports 61% increase in revenue

Finance - Cancer drug maker reports loss of $0.09 per share, provides clinical pipeline progress report

Finance - Cancer medical device maker gives support to 100,000 Lives Campaign

Finance - Cancer-focused drug delivery company to raise about $15.8 million through equity funding

Gastric Cancer - Methylation of GST-pi linked to Epstein-Barr virus-associated gastric carcinomas

Gastric Cancer - Morphological features of gastric noninvasive neoplasia described

Gastric Cancer - Multi-detector row CT used for T staging of gastric cancer

Gastric Cancer - Postoperative oral fluoropyrimidine compared to paclitaxel/oral fluoropyrimidine

Gastric Cancer - Risk factors for gastrointestinal malignancy delineated

Gastric Cancer - Sulfotransferase 1A1 polymorphism associated with gastric cancer risk

Gastroenterology - Notch signal blockade halts pancreatic cancer neurovascular progression

Gastrointestinal Stromal Tumors - Multidrug resistance proteins did not impair initial response of GIST to imatinib

Gene Expression - A novel survival-related gene controls apoptosis and tumorigenesis

Gene Research - HectH9 regulates transcriptional activation and tumor cell proliferation

Gene Therapy - Effect of epidermal growth factor receptor inhibitors on gliomas studied

Glioblastoma - Independent monitoring committee recommends that the PRECISE trial continue as planned

Glioblastoma - Virus-drug combination may have synergistic effect against brain cancer

Glioblastomas - Matrix-degrading proteases are expressed in human glioblastomas

Gliomas - PET and SPECT used to image low-grade glioma

HIV/AIDS Therapy - Incidence of squamous cell carcinoma of the anal canal among men has increased

HIV/AIDS-Related Lymphoma - SV40 gene expression occurs in a fraction of cells in some B-cell lymphomas in HIV/AIDS

Head & Neck Cancer - Antibody choice impacts vessel detection in oral mucosal tissues

Head & Neck Cancer - Risk of radiation-induced cancer in SCH patients deemed small

Head & Neck Cancer - Surgery and radiotherapy need to be implemented to achieve continuous remission

Head & Neck Cancer - Ultrasonographic carotid artery screening suggested in long-term head and neck cancer survivors

Head & Neck Cancer - Weekly docetaxel and radiation therapy was deemed feasible

Head & Neck Cancer Vaccine - HPV T cells have anti-tumor activity against head and neck cancer

Hematology - Recommended guidelines for molecular hematology outlined

Hematology - Research in hematology provides new insights

Hematology - Researchers detail new studies and findings in the area of hematology

Hematology - Researchers publish new studies and findings in the area of hematology

Histiocytoma - New grading system for malignant fibrous histiocytomas proposed

Hodgkin Lymphoma - Extended version of SEIQoL-DW validated in cohort of Hodgkin lymphoma survivors

Hormonal Cancer - Enhanced hormone glucuronidation may be protective against hormonal cancer

Human Papillomavirus - Bias in HPV genotype prevalence assessment is linked to commonly used primers

Human Papillomavirus Diagnostics - DNA purification method affects HPV genomic DNA detection from oral rinse samples

Human T-Lymphotropic Virus - HTLV-1-infected lymphocytic monkeys have reduced cell turnover

Imaging - Breast imaging PACS installed in public Stockholm Soder Hospital in Sweden

Imaging - Researchers' data advance imaging research

Immune Evasion - Viruses and tumor cells have strategies to evade CD8 cell recognition and destruction

Immunotherapy - Clinical efficacy of cancer immunotherapy targeting WT1 protein should be clarified

Kidney Cancer - Carboxyamidotriazole has an insignificant impact on advanced renal cell carcinoma progression

Legal Issues - Antitrust lawsuit filed against Bristol-Meyers Squibb in 2003 settled for $4.2 million

Leukemia - Adolescent survivors of acute lymphoblastic leukemia suffer psychological and physical pain

Leukemia - Cloretazine and ara-C chemotherapy regimen showed strong antileukemic activity

Leukemia - Hematopoietic cell transplantation followed reduced-intensity conditioning for leukemia therapy

Leukemia - Incidences of leukemia subtypes sorted by socioeconomic and occupational groups

Leukemia - Leukemia mortality related to ionizing radiation at Portsmouth Naval Shipyard

Leukemia - Link between NQO1 and pediatric acute lymphoblastic leukemias examined

Leukemia - Positive Dacogen injection data presented

Leukemia - Quantification of AML1-ETO fusion transcript used to prognosticate leukemia

Leukemogenesis - MEK kinase 1 essential for Bcr-Abl-induced STAT3 and self-renewal activity in ESCs

Liver Cancer - Miniaturized ultrasound arrays proposed for interstitial ablation and imaging

Liver Cancer - Recent findings in Liver Cancer described

Lung Cancer - Asbestosis was not a mandatory precursor for lung cancer in Wittenoom

Lung Cancer - Clinical features of lung cancer identified

Lung Cancer - Helical CT and FDG-PET used to identify lymph node mediastinal metastases

Lung Cancer - Low-dose gemcitabine infusion and cisplatin used to treat lung cancer

Lung Cancer - Lung carcinomas in Western Europe show low prevalence of human papillomaviruses

Lung Cancer - Mortality and cancer incidence in Ontario glass fiber workers studied

Lung Cancer - Nedaplatin and paclitaxel deemed effective for non-small cell lung cancer

Lung Cancer - Slug transcription factor promotes the invasion of lung adenocarcinoma

Lung Cancer Therapy - Combination ZD1839 and trastuzumab inhibit cell growth in non-small-cell lung cancer

Lymphoma - MabThera maintenance therapy shown to improves survival for patients with non-Hodgkin lymphoma

Macroadenomas - Strategies for management of invasive macroadenomas are needed

Medullary Thyroid Cancer - Prophylactic thyroidectomy used to treat hereditary medullary thyroid carcinoma

Melanoma - Dermoscopy patterns of cyclin D1 gene used to diagnose acral melanoma

Melanoma - Lupeol suppressed migration of malignant melanoma cells

Melanoma - O-6-benzylguanine and BCNU did not improve outcome of melanoma

Melanoma - Researchers provide details of new studies and findings in the area of melanoma

Melanoma - Surgical reconstruction of lentigo maligna defects discussed

Melanoma - hTERT expression could not be used in diagnosis of primary melanocytic lesions

Melanoma Therapy - Combination chemotherapy may be new option for metastatic skin cancer

Melanoma Vaccine - Cancer vaccines targeting tyrosinase show promise

Melanoma Vaccine - IL-7-dependent expansion and T cell persistence lead to tumor regression

Melanoma Vaccine - Melanoma survivin expression predicts poor disease outcome after polyvalent vaccine

Melanoma Vaccine - Vaccine expressing alpha(1,3)-galactosyl epitopes is effective against pre-existing melanoma

Meningioma - Leakage volume and permeability measured with dynamic contrast-enhanced MRI

Mergers & Acquisitions - Biopharmaceutical company stockholders approve proposal of merger with EpiCept

Mergers & Acquisitions - Drugmaker completes merger with Maxim Pharmaceuticals

Mergers & Acquisitions - Formal documentation entered for acquisition of HealthLinx

Mergers & Acquisitions - Pharmaceutical company to acquire Miikana Therapeutics

Mesothelioma - Met receptor is inhibited in mesothelioma

Multiple Myeloma - Orally active proteasome inhibitor induced apoptosis in multiple myeloma cells

Multiple Myeloma - VAD treatment affected levels of circulating serum proinflammatory mediators

Myelodysplastic Syndrome - Federal agency approves new treatment for subtype of myelodysplastic syndrome

Myelodysplastic Syndrome - U.S. FDA grants Revlimid NDA approval

Myeloid Leukemia - More than 90% of patients taking Gleevec for myeloid leukemia are alive after 4 1/2 years

Neuroblastoma - Gene described that halts spread of aggressive childhood cancer

Neurology - Radiosurgery used to treat primary central nervous system lymphoma of brain stem

Non-Hodgkin Lymphoma - Autoimmune disorders associated with risk for non-Hodgkin lymphoma

Non-Hodgkin Lymphoma - Positive interim results reported from phase I trial for CB3304 (noscapine) in non-Hodgkin lymphoma

Non-Hodgkin Lymphomas - Staging of non-Hodgkin lymphoma reported

Noncutaneous T-Cell Lymphoma - Encouraging responses reported with HuMax-CD4 in noncutaneous T-cell lymphoma

Occupational Exposure - Test method developed to assess spill and leakage from drug preparation systems

Oncology - Clonogens prevail before angiogenesis in irradiated tumors

Oncology - Findings in oncology provide new insights

Oncology - Galectin-3 phosphorylation leads to epithelial cell malignant transformation

Oncology - Recent findings in oncology provide new insights

Oncology - Recent studies add new data to oncology research

Oncology - Reports add new data to oncology research

Oncology - Research in oncology provides new insights

Oncology - Researchers detail new studies and findings in the area of oncology

Oncology - Thymic tumors in murine models maintain a large neovascular component

Oncology - Vascular endothelial growth factor bolsters prostate cancer-related osteoblast activity

Oral Cancers - 3-D invasion model used to study cancer cell invasion and cellular migration

Ovarian Cancer - Association between triazine herbicides and ovarian cancer risk remains vague

Ovarian Cancer - Combined treatment methods prolong survival in women with advanced ovarian cancer

Ovarian Cancer - Group issues position statement on intraperitoneal chemotherapy

Ovarian Cancer - Hyaluronan-linked beads help MRI follow angiogenic developments in ovarian cancer

Ovarian Cancer - Phosphatidylinositol 3-kinase inhibitor blocks ovarian tumor angiogenesis and vascular permeability

Ovarian Cancer - Study confirms established prognostic marker for recurrent ovarian cancer

Pain Management - Pain treatment analyzed among patients with incurable malignant tumors

Pain Management - U.S. FDA accepts investigational new drug application for Sativex

Palliative Care - Use of spirituality, psychotherapy and music in palliative cancer care examined

Pancreatic Cancer - Proteomic analysis used to diagnose pancreatitis and pancreatic adenocarcinoma

Pancreatic Ductal Adenocarcinoma - Protein overexpression influences pancreatic ductal adenocarcinoma cell growth

Pancreatic Tumors - Management algorithm of cystic pancreatic tumors developed

Patents - Company receives notice that European patent will be issued for optical biopsy system

Personnel - David T. Zava, PhD, appointed to board of Naturopathic College of Naturopathic Medicine

Personnel - Drug developer adds cancer specialist Ewa K. Carrier, MD, to scientific advisory board

Personnel - Jose L. Rodriguez named vice president of business development of specialty pharma

Personnel - Richard W. Dugan named to board of oncology-focused drug development company

Pharmaceutical Research - Imatinib synergizes with donor cell infusions for rapid molecular CML remission after ASCT

Product Licensing - Commercial license inked for the production of paclitaxel, taxane products from plant cell culture

Product Licensing - MedImmune licenses rights to XmAb proprietary engineered Fc domains

Product Licensing - Pharma company signs license agreement for European rights to Rapinyl

Prognostics - Poor differentiation linked to unfavorable outcome of hepatic endocrine tumors

Prostate Cancer - Accuracy of three-dimensional sonoelastography evaluated

Prostate Cancer - Advanced prostate cancer managed with first- and second-line chemotherapy

Prostate Cancer - Broader strategies needed for improving coping ability with sexual dysfunction

Prostate Cancer - Efficacy of androgen deprivation and radiotherapy for locally advanced prostate cancer assessed

Prostate Cancer - Increased Hsp27 facilitates androgen-independent progression in prostate cancer

Prostate Cancer - Lean body mass associated with risk of prostate cancer

Prostate Cancer - Misoprostol rectal suppositories did not prevent acute radiation proctitis

Prostate Cancer - PSP-94 and PCK3145 examined as therapeutic modalities for prostate cancer

Prostate Cancer - Parameters for treatment decisions for salvage radiation therapy discussed

Prostate Cancer - Pathogenesis and treatment of prostate cancer bone metastases discussed

Prostate Cancer - Preoperative PSA kinetics predict post-radical retropubic prostatectomy outcomes

Prostate Cancer - Prostate gland volume used to predict biopsy results in men 70 years or older

Prostate Cancer - Prostate-specific antigen kinetics and clinical factors used to select patients

Prostate Cancer - Recent studies add new data to Prostate Cancer research

Prostate Cancer - Rectal balloons filled with 60 ml air are recommended

Prostate Cancer - Relationship of vitamin E and prostate cancer benefits not resolved, men's newsletter says

Prostate Cancer - Rewards justify costs of phase III prostate cancer prevention trials

Prostate Cancer - Role of 5ARIs for prostate cancer chemoprevention needs further elucidation

Prostate Cancer - Routine transition zone biopsy did not improve prostate cancer detection rate

Prostate Cancer - Study shows PSP94 diagnostic marker better at detecting aggressive prostate cancer

Prostate Cancer - Tumor length, Gleason score and prostate volume predicted insignificant cancer

Prostate Cancer - Use of radiotherapy to manage clinically localized prostate cancer reviewed

Prostate Cancer Diagnosis - Lowering prostate-specific antigen threshold for biopsy benefits older men

Prostate Cancer Therapy - Balsalazide prevented acute radiation-induced proctosigmoiditis in prostate cancer patients

Proteomics - Recombinant endostatin generates a U-shaped dose-response curve

Proteomics - Tumor endothelial marker 7 is a prerequisite for endothelial cell capillary morphogenesis

Pseudotumors - Radiologic features of inflammatory pseudotumors described

Radiotherapy - Method for target motion measurement without implanted markers validated

Radiotherapy - Renal dysfunction occurred after total-body irradiation for leukemia

Rectal Cancer - Clinical evaluation of therapy response could not be used to make treatment decisions

Rectal Cancer - Distal resection margin of 2 cm is adequate in rectal adenocarcinoma

Rectal Cancer - Patient outcome after surgical excision of T4 rectal cancer analyzed

Rheumatoid Arthritis - Positive preliminary results reported from phase Ib trial of CH-1504

Smoking Cessation - Treatment options for smoking cessation therapy in aviators discussed

Squamous Cell Cancer Vaccine - Anti-HER-2 DNA vaccine protects against squamous cell carcinomas

Squamous Cell Carcinoma - Case of primary squamous cell carcinoma of the stomach reported

Squamous Cell Carcinoma - New guide to mandibular resection for oral squamous cell carcinoma proposed

Squamous Cell Carcinoma - Squamous cell carcinoma was more prominently displayed with delayed luminescence

Statins - Statins have neutral effect on risk of cancer

Stem Cell Transplantation - Busulfan-thiotepa followed by SCT toxic/ineffective in relapsed irradiated medulloblastoma

Stem Cell Transplantation - Graft manipulation results in well-characterized transplants with minimal GVHD risk

Surgical Technology - Incidence of bladder perforation after transurethral bladder surgery evaluated

Surgical Technology - Pre-mental foramen mandibulotomy for tumor resection described

Surgical Technology - Resection of T3 carcinomas of upper thoracic esophagus linked to poor outcome

Surgical Technology - Split orbicularis myomucosal flap used for lower lip reconstruction

Surgical Technology - Surgical outcome of ileal pouch-anal anastomosis reviewed

Surgical Technology - Transurethral bladder tumor resection performed under supervision deemed safe

Testicular Cancer - Primary surveillance resulted in fewer testicular cancer therapeutic interventions

Testicular Germ Cell Tumor - Testicular germ cell tumors exhibit evidence of hormone dependence

Thyroid Cancer - Gene mutation linked to poor outcome in thyroid cancer patients

Thyroid Cancer - Selective use of postsurgical radioiodine in follicular thyroid cancer advised

Thyroid Gland - Loss-of-function deletion in sodium/iodide symporter found in thyroid adenoma

Tobacco Use - Scientists developing behavior- and physiology-based cancer prevention program

Tonsillar Lymphoma - Diagnosis of tonsillar lymphoma in pediatric patients discussed

Transitional Cell Cancer - Ki-67 over-expression used to prognosticate transitional cell carcinoma

Tumors - Cytotoxic T cell functions are directly targeted during tumor evasion of immune surveillance

Vaginal Intraepithelial Neoplasia - Trichloroacetic acid proves effective for low-grade vaginal intraepithelial neoplasia

Virology - Cytoplasmic phosphoproteins alter cellular morphology and disrupt adhesion in KSHV

Vulvar Cancer - Bone metastases should be considered in women with a history of vulvar cancer

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