Cancer Vaccines
Findings advance knowledge in Cancer Vaccines research
Published in Cancer Weekly, January 24th, 2006
Study 1: Exosomes show potential in the immunotherapy of cancer.
"Dendritic-cell-derived exosomes (DEX) secreted after dendritic cell loading with tumor peptides were found to mediate tumor rejection in mice. This observation prompted us to demonstrate that MHC class I/peptide complexes harbored onto exosomal membranes were capable of priming cytotoxic T cells and to mediate rejection of tumors expressing the relevant antigens," scientists in France report.
"Moreover, DEX also promote NK cell activation in immunocompetent mice and...
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Source: Cancer Weekly (2006-01-24)
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