Acute Myeloid Leukemia
Pathogenic mechanism differed in cytogenetic subgroups of acute myeloid leukemia
Published in Cancer Weekly, January 24th, 2006
"It is well known that the different cytogenetic subgroups of AML show different age-specific frequencies," investigators in Germany reported.
"For example, balanced translocations tend to be found in younger patients while complex aberrant karyotypes are usually found in elderly patients with AML. However, detailed data on the population-based age-dependent incidences of distinct cytogenetic subtypes as well as of molecular mutations are lacking. We evaluated the population-based age-specific incidences of different cytogenetic subgroups in 2555...
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Source: Cancer Weekly (2006-01-24)
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