Published in Cancer Weekly, January 31st, 2006
According to a study from Scotland, "Up to 5% of patients with melanoma have a family history of a first-degree relative also being affected. [The scientists' goals were] to study such families for germline mutations [and] to help clarify the gene-environment interaction in melanoma etiology."
"Thirty-two families in Scotland with melanoma in two or more first-degree relatives are reported for the first time. Peripheral blood DNA was extracted, and denaturing high-performance liquid chromatography analysis performed on exons 1 alpha and 2 of the CDKN2A gene and their...
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