Published in Cancer Weekly, February 7th, 2006
According to recent research published in the journal Oncology Reports, "The ubiquitin-proteasome system plays a critical role in the regulation of programmed cell death. Proteasome inhibitors induce apoptosis in various cancer cells and have antitumor effects in murine tumor models."
"In the present study, we investigated whether the cell-permeable proteasome inhibitor MG132 reduced the growth of a human pancreatic cancer cell line through induction of apoptosis in vitro. The effects of MG132 (.125-1.000...
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