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Susan Hasty, Publisher Table of Contents . . . February 14th, 2006 Non-Subscriber - Summaries Only Related Areas: Other Issues in Cancer Weekly | Other Publications
Bone Tumors - FDG-PET used to detect bone tumors when bone scintigraphy gave negative findingsBreast Cancer - New breast magnetic resonance imaging technique endorsedColon Cancer - Use of artepillin C helps prevent colon cancerDrug Resistance - Chromosomal alterations resulted in drug resistance in cancer cellsProstate Cancer - Antiprostasome antibody titer used as supplemental prostate cancer markerAbdominal Tumors - Abdominal position shifts detected with radiation-planning CT scansAdverse Drug Reaction - CYP17 polymorphism may influence tamoxifen-induced hepatic steatosisAlcoholic Hepatitis - Glycine may prevent liver cancer by impeding angiogenesisAmputation - Sarcoma identified as leading cause of limb amputationAnalgesia - Recommendations made on safety of cancer patient-controlled analgesiaAngiology - Only nonalcoholic fraction of red wine may protect DNA from oxidative damageAntisense Technology - Antisense oligo DNA and small interfering RNA suppress malignant cancer cell phenotypesApoptosis - PDCD2_C domain might not be universally associated with apoptosisApoptosis - Transcription inhibition proposed as potential strategy for cancer therapeuticsAstrocytomas - Fractionated stereotactic reirradiation deemed effective in gliomasAutoimmune Disease Research - NovImmune SA files IND in the Netherlands for a human antibody that targets the CD3 antigenAwards - Komen Tulsa affiliate awards $340,000 to local organizations to aid breast cancer fightBarrett Esophagus - Cryoablation used to eradicate Barrett esophagusBarrett Esophagus - Progression to high-grade dysplasia in women with Barrett esophagus is similar to menBladder Cancer - New findings in the area of bladder cancer describedBladder Cancer - Published study of protein-based bladder cancer test shows 99% of malignancies foundBladder Cancer - Researcher reports NMP22 BladderChek Test detects three times more cases of bladder cancerBladder Cancer - Tobacco smoking and GSTP1 polymorphism linked to bladder carcinomaBladder Urothelial Cancer - COX-2 protein expression related to poor outcome of bladder urothelial carcinomaBone Marrow - Blimp-1 is required for formation and maintenance of long-lived plasma cellsBone Metastases - (18)FDG-PET should complement bone scintigraphy for detecting bone metastasesBrain Cancer - 3 T deemed more beneficial than 1.5 T in brain tumor magnetic resonance imagingBrain Cancer - Anti-angiogenic therapy in pediatric neuro-oncology discussedBrain Cancer - Atypical teratoid/rhabdoid tumors of the central nervous system identifiedBrain Cancer - Infections could contribute to adult brain tumorsBrain Cancer - No link shown between mobile phone use and increased risk of glioma tumorsBrain Cancer - Recent findings in brain cancer describedBrain Metastases - Role of chemotherapy in brain metastases examinedBrain Tumor - Restoring neurogenesis might treat cognitive sequelae of brain tumor therapyBreast Cancer - Adiponectin expression induced apoptosis in MDA-MB-231 breast cancer cellsBreast Cancer - Adjuvant breast cancer therapy needs to move away from one-fits-all mentalityBreast Cancer - Androgen receptor activity reduces cancer risk in African-American womenBreast Cancer - Calcium signaling in cancer and vitamin D examinedBreast Cancer - Clinical trial tests delivery of chemotherapy directly to breast ductsBreast Cancer - Combined gene therapy effect revealed in syngeneic murine breast cancer modelsBreast Cancer - Declines in mortality from breast cancer represent progress in disease controlBreast Cancer - Dependable social relationships predicted survival in breast carcinoma patientsBreast Cancer - High-dose chemotherapy improved survival in breast cancer patientsBreast Cancer - Identification of all sentinel nodes may reduce risk of breast cancer recurrenceBreast Cancer - Mapping for sentinel lymph node biopsy is enhanced with combined diagnostic modalitiesBreast Cancer - Multicenter phase II study of MKC-1 initiated in breast cancerBreast Cancer - Positron emission tomography for breast cancer deemed cost-effective in CanadaBreast Cancer - Prognostic factors in breast cancer change over timeBreast Cancer - Recent studies add new data to breast cancer researchBreast Cancer - Reports add new data to breast cancer researchBreast Cancer - Researchers detail new studies and findings in the area of breast cancerBreast Cancer - Role of autoimmunity in breast cancer has broad implications in therapy target discoveryBreast Cancer - Solid-state gamma camera used to depict sentinel lymph nodes in breast cancerBreast Cancer - Spanish-preferring Latinas experienced delays in care for breast cancerBreast Cancer - Spleen tyrosine kinase mediated breast tumor suppressionBreast Cancer - Study examines participation in online support groups for breast cancer patientsBreast Cancer - Survival after diagnosis of breast cancer varied in SwitzerlandBreast Cancer - Ultrasonography detected infraclavicular lymph node metastases in breast cancerBreast Cancer - Unsatisfactory coping and defending mechanisms linked to risk of breast cancerBreast Cancer - Vaginal estrogen may pose risks to patients taking new breast cancer drugsBreast Cancer Prevention - Physician education would enhance recruitment of Asian-American women into cancer researchBreast Cancer Prevention - Review examines therapeutic value of selective estrogen receptor modulators in breast cancerBreast Cancer Risk Factors - Breast cancer risk for Hispanic women increases with length of residency in U.S.Breast Cancer Risk Factors - Dietary calcium/dairy consumption have slight inverse association with breast cancer riskBreast Cancer Risk Factors - Dietary factors may influence mammographic density and breast cancer riskBreast Cancer Risk Factors - Some foods in traditional southern diet may reduce risk of invasive breast cancerBreast Cancer Screening - Breast cancer survival is linked more to early diagnosis than to differential treatmentBreast Cancer Survival - Extended benefit for women after 5 years of tamoxifen therapy is observed with letrozoleBreast Cancer Survival - Regional differences in breast cancer survival are explained by low diagnostic activityBreast Cancer Therapy - Report advocates use of epirubicin for adjuvant breast cancer chemotherapyBreast Cancer Therapy - Risk of recurrence is reduced in women treated with letrozole for breast cancerBreast Cancer Therapy - Studies add new findings to breast cancer therapy body of knowledgeBreast Cancer Vaccine - ST6GalNAc I expression in breast cancer cells enhances tumorigenicityBreast Disease - Body fat at young age may reduce incidence of breast disease in premenopausal womenBusiness & Finance - License agreement for cancer therapy satraplatin to yield $40 million in milestone paymentsBusiness Update - Circulating tumor cells are predictive of outcome for breast cancer patientsCancer Cell Biology - icb-1 gene expression is inducible in breast and ovarian cancer cellsCancer Diagnostics - Current imaging algorithm and new developments in cancer diagnostics reviewedCancer Diagnostics - Tumor markers and (18)FDG-PET could detect tumor recurrencesCancer Drugs - Access to drugs for cancer varied across CanadaCancer Drugs - Cytotoxicity of MDL 72527 demonstrated in cancer cellsCancer Drugs - Recommended dose of irinotecan in pediatric cancer patients announcedCancer Gene Therapy - Adeno-associated virus is tumoricidal because of inhibited angiogenesisCancer Gene Therapy - Capsid-modified adenovirus efficiently infects tumor endothelial cellsCancer Gene Therapy - RNA interference enhances the cisplatin sensitivity of colorectal adenocarcinoma cellsCancer Gene Therapy - Thymidylate synthase expression is inhibited by retrovirally introduced siRNA geneCancer Gene Therapy - Transfected, microencapsulated cells and ifosfamide treat peritoneal cancerCancer Genetics - Etheno-DNA adducts may be lead markers for inflammatory cancer-prone diseasesCancer Immunology - Interleukin-1 receptor antagonist arrests the oncological effects of interleukin-1 betaCancer Immunotherapy - Antibody with human sugar structures can be produced in non-mammalian hostCancer Incidence - Extra X chromosome does not appear to increase cancer incidence, mortality in womenCancer Inhibition - Polymeric polyphenols inhibited hematologic tumor cell linesCancer Prevention - Lipid peroxidation was examined as possible chemoprotective mechanism for breast cancerCancer Prognostics - White blood cell count, inflammation predict cancer deathsCancer Research - Crystal structure holds clue to Aurora kinase inhibitor's efficacy against Gleevec-resistant kinaseCancer Research - New development enables longer survival of cells, allowing opportunity for measurementCancer Research - Pennsylvania may opt to give tax refund to breast, cervical cancer researchCancer Risk Factors - BRCA1 deficiency is linked to aberrant estrogen biosynthesis associated with cancer riskCancer Risk Factors - Cancer incidence and mortality in UK semiconductor workers examinedCancer Risk Factors - Inconclusive BRCA1/2 testing results create anxiety in women about cancer riskCancer Survivors - Divide between cancer survivorship initiatives and minorities needs bridgingCancer Survivors - Psychosocial problems faced by adult cancer survivors analyzedCancer Therapy - 2C4 disrupts HER kinase signaling pathway, inhibits ovarian carcinoma cell growthCancer Therapy - Antiproliferative and apoptosis-inducing activity of Brucea javanica shownCancer Therapy - By 2020 there will be 30M people living with cancerCancer Therapy - Calcitriol plus NSAIDs may be potential therapy for prostate cancerCancer Therapy - Cancer phenotypes are suppressed through a multifunctional actin-binding proteinCancer Therapy - Cancer treatment system non-invasively focuses heat on drug-injected regionCancer Therapy - High-risk profiles across cancer continuum defined via multidimensional approachCancer Therapy - Leptosins inhibit DNA topoisomerases and induce apoptosisCancer Therapy - Long-term side effects of adjuvant chemotherapy reviewedCancer Therapy - Meisoindigo curtails angiogenic processes in chronic myelogenous leukemia cellsCancer Therapy - Mucosectomy is a sufficient therapy for early squamous cell of the esophagusCancer Therapy - New findings in the area of cancer therapy describedCancer Therapy - New research in the area of cancer therapy detailedCancer Therapy - Oncolytic herpes simplex virus is useful in therapy of metastatic pleural cancerCancer Therapy - Oral cancer plasma tumor marker identified with proteomics technologyCancer Therapy - Polysaccharide-rich substance with antitumor activity isolated from black currant juiceCancer Therapy - Positive early responses reported on use of HepaSphere Microsphere for liver cancerCancer Therapy - Preclinical data demonstrating anticancer activity of Quadramet in multiple myeloma publishedCancer Therapy - Report presents useful techniques for evaluating cancer control effortsCancer Therapy - Researchers' work adds to cancer therapy body of knowledgeCancer Therapy - Study explored zebularine metabolism by aldehyde oxidase in hepatic cytosolCancer Therapy - UHRF1 required in tumor cell proliferationCancer Vaccine - Dendritic cell therapy with IFN-alpha suppresses tumors in colorectal cancerCancer Vaccine - Gastric cancer cell-dendritic cell hybrids induce tumor-specific T cellsCancer Vaccine - Melanoma patient has spontaneous CTL response to MAGE-A3 peptideCancer Vaccine - NKT lymphocytes confer immunity via tumor-capturing dendritic cellsCancer Vaccine - Report summarizes European Conference on Progress in Vaccination Against CancerCancer Vaccines - New data illuminates research in cancer vaccinesCancer Vaccines - Researchers detail new studies and findings in the area of cancer vaccinesCarcinogenesis - Possibility examined of thiamin deficiency as major cause of some tumorsCervical Cancer - HPV typing from paraffin-embedded sections of cervical cancers deemed feasibleCervical Cancer - Increased GRP94 expression in cervical cancer cells is linked to decreased X-ray sensitivityCervical Cancer - Life sciences company inks MOU through U.S. State Department's Bio-Industry InitiativeCervical Cancer - New data illuminates research in cervical cancerCervical Cancer Screening - Human papillomavirus-DNA testing may be useful to triage patients for colposcopyCervical Cancer Screening - Rate of cervical cancer among Zimbabwe women highlights value of screening programsCervical Cancer Vaccine - Study examined pediatricians' intention to administer HPV vaccineCervical Cancer Vaccine - Transcutaneous immunization protects against HPV-induced tumorsCervical Lymph Node Metastasis - Tc-99m-MIBI SPECT and CT used in evaluation of cervical lymph node metastasisChemotherapy - Researchers describe findings in chemotherapy studiesChronic Myelogenous Leukemia - Newly discovered Bcr-abl kinase inhibitor may have therapeutic potential in CMLClinical Trials - Dosing begun in anticancer drug trial in patients with metastatic colorectal cancerClinical Trials - Phase 1 clinical trial of oral heat shock protein 90 inhibitor for cancer initiatedClinical Trials - Positive new survival findings reported from phase II and III clinical trials of orBecCollaborations - Anticancer drug discovery collaboration signedCollaborations - Strategic alliance agreement establishes Molecular Center of ExcellenceColon Cancer - Colon cancer survival linked to regional lymph node metastasisColon Cancer - Estrogen receptor-beta gene in women is associated with increased colorectal cancer riskColon Cancer - Sphingosine kinase 1 levels rise in colon carcinomasColon Cancer - Use of adjuvant chemotherapy in colon cancer differs among race, gender, and ageColorectal Cancer - Asian-Americans have low colorectal cancer screening ratesColorectal Cancer - Clinicopathological features predicted microsatellite instability in colorectal carcinomasColorectal Cancer - Colorectal cancer in colonic Crohn disease linked to DNA-aneuploidyColorectal Cancer - Contrast-enhanced ultrasonography used during surgery for CRC liver metastasesColorectal Cancer - Dietary fiber intake was not correlated with lower risk of colorectal cancerColorectal Cancer - Extracolonic findings during colorectal cancer screening were rarely of clinical significanceColorectal Cancer - Use of germline DNA pharmacogenetics to study colorectal tumor DNA validatedColorectal Cancer - Use of virtual CT colectomy suggested for laparoscopic colorectal surgeryComplementary & Alternative Medicine - Orbignya phalerata Mart activates peritoueal macrophages, which may assist in tumor treatmentComplementary & Alternative Medicine - Alternative medicine remedies might stimulate leukemic cell viabilityComplementary & Alternative Medicine - Anti-inflammatory potential of Antrodia camphorata demonstratedComplementary & Alternative Medicine - Blueberry flavonoids inhibited MMP activity in DU145 human prostate cancer cellsComplementary & Alternative Medicine - The plant compound hyperforin blocks angiogenesisDNA Research - Positive data presented from test of alkylating anthraquinone on multiple cancer cell linesDNA Research - Radiation sensitivity of fresh peripheral blood cells related to cancer statusDiagnostics - Angiogenic protein in nipple fluid detects breast cancer risk in womenDiagnostics - Chest CT has low sensitivity for distant metastasesDiagnostics - Clinical findings and cytology in disseminated TB can mimic anaplastic thyroid cancerDiagnostics - Diagnostics company to supply test kits, including VScan, to China hospital in Anhui ProvinceDiagnostics - Extra-axillary sentinel node biopsy may help doctors manage early breast cancerDiagnostics - Features of recurrent lung cancer cells may indicate depth of invasion in bronchial wallDiagnostics - Interfacial properties of tissues may lead to biophysical marker of cervical cancerDiagnostics - Intraoperative sentinel node detection enhances the staging of invasive bladder cancerDiagnostics - Near-infrared spectroscopy is potential in vivo diagnostic of pancreatic cancerDiagnostics - Novel approach facilitates tumor classification from gene expression profilesDisease Associations - Acromegaly associated with increased risk of developing colonic tumorsDrug Development - Basal cell carcinoma phase I trial to be completed in first half of 2006Drug Development - Multiple Myeloma Research Consortium selects preferred contract research organizationDrug Development - Patients with colorectal hepatic metastases may benefit from irinotecan-based adjuvant chemotherapyDrug Development - Phase I study of EM-1421 underway targetting tumors unresponsive to conventional therapyDrug Development - Reports describe recent advances in drug development researchDrug Development - Two antitumor agents can modify cell-bound DNADrug Development - Withdrawal of EMEA marketing application for rubitecan capsules announcedDrug Resistance - Transcription factors and drug resistance discussedDuctal Carcinoma In Situ - Biological variables and prognosis of ductal carcinoma in situ discussedEmbryonal Cancer - Embryonic environment can 'normalize' tumor cells during postimplantation developmentEndocrinology - Recent findings in endocrinology describedEndometrial Cancer - Estrogen exposure combined with inflammation may foster development of endometrial cancerEndometrial Cancer - No chemoprotective effect for endometrial cancer was observed with regular aspirin useEndometrial Cancer - Supplemental radiation therapy beneficial for stage I endometrial cancerEnzymology - Cyclooxygenase-2 uses toll-like receptors to drive microbe-induced cancer invasionEnzymology - Researchers publish new studies and findings in the area of enzymologyEsophageal Cancer - Appropriate staging system for esophageal carcinoma identifiedEuosmia - Euosmia discovered as rare form of parosmiaFanconi Anemia - Frog eggs help researchers understand Fanconi anemiaFinance - Cancer-focused biopharma company announces $21.6 million tax assisted financingFinance - Genomics company reports losses of $0.10 per shareFinance - Immunotherapy company closes additional $1.2 million in investments
Finance - Immunotherapy developer announces proposed offering of common stockFinance - NCI SPORE grant will fund basic and translational breast cancer researchFinance - Protein diagnostic products company closes $7 million financingFinance - orBec maker secures $6 million equity commitment from Fusion CapitalFitness & Wellness - Dietary changes and physical activity may improve the outcomes of breast cancer patientsGastric B-Cell Lymphoma - Functional promotor polymorphism of TNF-alpha linked to gastric B-cell lymphomaGastric Cancer - Clinical characteristics and management of esophagogastric tumors discussedGastric Cancer - Elderly patients with gastric cancer treated by diathermic knife dissectionGastric Cancer - Laparoscopically assisted distal gastrectomy with D2 lymph node dissection feasibleGastric Cancer - Loss of ADAM23 function implicated in gastric carcinogenesisGastric Cancer - MGr1-antigen regulates multidrug resistance in gastric cancer cellsGastroenterology - Inhibitor of DNA binding protein blockade halts gastric cancer metastasisGastroenterology - SP5 identified as a downstream gene of the beta-catenin/Tcf pathwayGastrointestinal Stromal Tumor - STI571 was effective treatment for gastrointestinal stromal tumorGene Therapy - Transcriptional control of therapeutic genes targets proliferating tumor cellsGenetic Research - Role of tumor suppressor retinoblastoma protein Rb as a transcription regulator examinedGenetic Research - Tumor suppressor genetics reviewedGenetics & Genomics - Differentially methylated promoters identified in tumor cell linesGenetics & Genomics - Genes associated with telomerase activity identified in esophageal carcinoma cell linesGenetics & Genomics - Genomic alterations noted in study may help explain mechanisms of lung cancerGlioma - DTI used to individualize radiotherapy target volumes in glioma patientsGlioma - Radiotherapy is gaining ground as therapy option for childhood low grade gliomaGraft-versus-Host Disease - CD8+ SCs identified that generate and sustain allogeneic T-cell subsets in GVHD reactionsGynecological Cancer - Nedaplatin exhibited strong antitumor activity in gynecological carcinomasHead & Neck Cancer - Carboplatin and raltitrexed used to treat head and neck squamous cell carcinomaHead & Neck Cancer - Cervicofacial and cervicothoracic rotation flaps used to reconstruct facial defectsHead & Neck Cancer - Chemoradiotherapy with taxotere and cisplatin used in head and neck cancerHead & Neck Cancer - Head and neck cancer patients experienced delays in accessing clinical resourcesHelicobacter Pylori - H. pylori -positive gastric mucosa is associated with lymphoid lymphomaHemangioendothelioma - Wide local excision recommended for epithelioid hemangioendotheliomaHematology - Angiogenic factors may influence the outcomes of adults with acute lymphoblastic leukemiaHepatitis C Virus - Hepatitis C virus E2 inhibits apoptosisHepatitis C Virus - Researchers' findings advance hepatitis C virus researchHepatocellular Cancer - Human hepatocellular carcinoma-related biomarkers identifiedHepatocellular Cancer - Model described for nonalcoholic steatohepatitis and hepatocellular carcinomaHepatocellular Cancer - Protein kinase C alpha expression is regulated in human hepatocellular carcinomaHepatocellular Cancer - Reports describe recent advances in hepatocellular cancer researchHepatocellular Cancer - Ser-mutated DNA can be quantitatively analyzed by mass spectrometryHepatocellular Cancer - Serum KL-6 serves as a tumor marker for hepatocellular carcinoma in HCV patientsHereditary Cancer - Family System Illness model offered to patients and families coping with cancerHilar Cholangiocarcinoma - Resection recommended for idiopathic strictures with presumed malignancyHodgkin Disease - Creation of a breast health program for female survivors of Hodgkin disease advocatedHuman Papillomavirus - Human papillomavirus in adolescents could lead to genital abnormalitiesHuman Papillomavirus - Study examined value of combined Pap and HPV testing in screening for cervical abnormalitiesImaging - Hypericin helps differentiate between glioblastoma and neurons in vitroImaging - Magnification endoscopy image analysis can aid diagnosis of gastric tumorsImaging - Optical coherence tomography useful for imaging laryngeal microstructureImaging - Radiotherapy equipment supplied to London hospitalImaging - Recent findings illuminate research in imagingInterleukin-2 - Regulatory T cell depletion enhanced vaccine-mediated immunity in cancer patientsKidney Cancer - Functional simulation of renal cancer in virtual reality environments designedLaryngeal Cancer - Survival rate of patients with laryngeal cancer analyzedLegal issues - Breach of contract lawsuit filed against Advanced Magnetics, Inc.Leukemia - Allo-BMT reduced relapse risk of leukemia but did not improve survivalLeukemia - Changes in bone mineral density in survivors of childhood leukemia analyzedLeukemia - Comparative genomic hybridization used to analyze Japanese B-CLLLeukemia - Coping linked to survival in leukemia patients with bone marrow transplantsLeukemia - Dose intensification improves outcome of leukemiaLeukemia - Elderly patients with acute lymphoblastic leukemia treated with imatinibLeukemia - Hairy cell leukemia developed in patient after cardiac transplantationLeukemia - Importance of cytogenetics in diagnosis of leukemias assessedLeukemia - Leukemia xenografts are inhibited by adenovirus-mediated tissue inhibitorLeukemia - Move towards pathogenesis-oriented therapy of acute myeloid leukemia warrantedLeukemia - New findings in leukemia describedLeukemia - New findings in the area of leukemia detailedLeukemia - Outcome in childhood acute myeloid leukemia found to be still unsatisfactoryLeukemia - Poor treatment outcomes in children with leukemia owed to low remission rateLeukemia - Recent findings in leukemia describedLeukemia - Research in leukemia provides new insightsLeukemia - Researchers publish new studies and findings in the area of leukemiaLeukemia - TRAIL proposed as anticancer agent in acute myeloid leukemiaLeukemia - Treatment concepts of acute promyelocytic leukemia discussedLeukemia - Verapamil analogues display multidrug reverting activity toward leukemia cellsLiver Cancer - Researchers provide details of new studies and findings in the area of liver cancerLiver Disease - Oxidative cellular damage occurs often in non-alcoholic fatty liver diseasesLiver Function - Loss of function of liver retinoic acid leads to steatohepatitis and liver tumorLung Cancer - Data advance knowledge in lung cancer researchLung Cancer - Endobronchial ultrasound-driven biopsy used to diagnose peripheral lung lesionsLung Cancer - High-resolution CT used to classify shape of pulmonary nodulesLung Cancer - Human lung cancer tumors are suppressed by a nuclear export mediatorLung Cancer - Indian herbal medicine used to treat lung cancerLung Cancer - Iodide sensitizes non-small cell lung cancer cells to ionizing radiationLung Cancer - New imaging technology detects pulmonary nodulesLung Cancer - Novel EGFR gene mutation could improve lung cancer patients' response to therapyLung Cancer - Palliative radiation actually a cure for some lung cancer patientsLung Cancer - Radiation therapy and paclitaxel used to treat non-small cell lung cancerLung Cancer - Report issues failing grades for progress being made against lung cancerLung Cancer - Reports advance knowledge in lung cancer researchLung Cancer - Research add new data to lung cancer body of knowledgeLung Cancer - Topotecan/ifosfamide used to treat patients with platinum refractory lung cancerLung Cancer - Tumor diameter of non-small cell lung cancer correlated with long-term survivalLymphoma - Neutrophils found to be activated in cutaneous T-cell lymphomaLymphoma - New hope of cure shed on primary splenic lymphomaMalignant Glioma - Phase I recurrent malignant glioma trial 6-month follow-up complete, reovirus is well-toleratedMarket Analysis - More angiogenesis inhibitors expected to reach market in next 5 years, according to reportMedical Devices - NeoMatrix selects medical device developer to manufacture breast cancer screening systemMedical Devices - The RBE of the MIT epithermal neutron beam has been determined in a murine modelMedicare - Medicare contractor establishes reimbursement coverage policy for Oncotype DX breast cancer testMedicare - Medicare shifted to an Average Sales Price-based reimbursement systemMedulloblastoma - Tumor suppressors collaborate with Patched to suppress medulloblastoma formationMelanoma - Computer-aided diagnosis of melanocytic lesions proved usefulMelanoma - Invasive skin cancer a growing problem among HispanicsMelanoma - Low-dose chemobiotherapy is effective in treatment of metastatic melanomaMelanoma - Recent findings in melanoma provide new insightsMelanoma - Ultrasound used to map lymph node and subcutaneous metastases of melanomaMergers & Acquisitions - Biosil Limited and Nagor Limited schedule closing of medical products company acquisitionMultiple Myeloma - FDG-PET detected more lesions than MIBI scan in patients with multiple myelomaMultiple Myeloma - Imexon combined with cytotoxic agents to improve therapeutic activity in myelomaMyeloma - Use of imatinib in patients with refractory/relapsed myeloma had no effectNanotechnology - Nanoparticles can be used for the optical imaging of tumor E-selectinNasopharyngeal Cancer - Nasopharyngeal cancer treated by chemoradiotherapy and accelerated fractionationNasopharyngeal Cancer - Time for LMP-1 regression inversely related to nasopharyngeal cancer controlNasopharyngeal Cancer - Wound treatment therapies in nasopharyngeal cancer patients comparedNeuroscience - Prion-protein 1 interaction promotes neuritogenesis and neuroprotectionNon-Hodgkin Lymphoma - TNF and lymphotoxin alfa polymorphisms related to poor outcome in non-Hodgkin lymphomaNon-Hodgkin Lymphoma - Vaccine boosts survival in patients with aggressive non-Hodgkin lymphomaNuclear Medicine - Standards authority reports on safety of nuclear medicine proceduresOligonucleotides - Splicing-sensitive microarrays detect and measure alternative splicingOncology - Exfoliation of fresh tumor tissue produces samples suitable for molecular profilingOncology - Recent findings in oncology provide new insightsOncology - Researchers publish new studies and findings in the area of oncologyOral Cancer Vaccine - DNA vaccine is effective against oral papillomavirus-linked oral cancerOsteosarcoma - TNSALP, PHEX and MEPE induced by beta-glycerophosphate in osteosarcoma cellsOvarian Cancer - Aggressive surgery benefited optimally debulked patients with ovarian cancerOvarian Cancer - NH2-terminally truncated p73 isoforms predicted poor prognosis in ovarian cancerOvarian Cancer - Ovarian tumor xenografts are imaged and treated using sodium iodide symporter-mediated radioiodideOvarian Cancer - Tumor protein D52 is overexpressed in ovarian cancerOvarian Cancer - Underlying mechanism connecting endometriosis and ovarian cancer needs definingOvarian Cancer Risk Factors - Endometriotic lesions are related to subsequent risk of ovarian cancersPancreatic Cancer - Congenital anomalies of spleen mimicked hematological disorders and solid tumorsPancreatic Cancer - Pancreatic head resection performed with low mortality in specialized unitsPancreatic Cancer - Researchers' findings advance pancreatic cancer researchPancreatic Cancer - Two cytologic patterns noted in invasive ductal adenocarcinoma of the pancreasPatents - Pharma company receives patent covering Provecta in conjunction with ultrasound imagingPatents - U.S. patent office grants allowance in biopharm company's second organic arsenic casePersonnel - AMD drug developer names John L. Armstrong, Jr. CEOPersonnel - Barbara Wallner, PhD, named senior VP for technical operations of cancer-focused companyPersonnel - Biomedical funding company promotes Chad W. Souvignier to directorPersonnel - Biopharma company builds drug-development team through new hires and promotionPersonnel - Biopharma company hires Mark W. Salyer as executive vice president of sales and marketingPersonnel - Biotech company signs investment banking agreement with Janney Montgomery ScottPersonnel - Kevin J. Buckman, MD, named to medical advisory board of medical diagnostics companyPersonnel - Lloyd Sanders named vice president of sales and marketing for Genasense developerPersonnel - Meghan Fitzgerald joins cancer drug developer as chief business officerPersonnel - Pharma company announces the appointment of Anatole Klyosov as chief scientistPersonnel - Pharma company appoints Jeff Himawan to board of directorsPersonnel - Stephen T.D. Dixon, CFO of cancer-focused company, resignsPhilanthropy - Cancer organization awards $105,000 in grants for cancer survivorship and outreachPhilanthropy - Financial services company extends commitment to underwrite children's health organization eventsPhilanthropy - Online grocery delivery company customers donate $12,000 to Hope Chest for Breast CancerPhysiology - Microtubules have differential roles in megakaryocyte proplatelet formationPituitary Tumors - PRL secretion, tumor size and operation date predicted neurosurgical outcome in pituitary tumorsProduct Licensing - Drug development company licenses formulation of opiate analgesic fentanyl for JapanProstate Cancer - A replicating adenovirus is useful for the treatment of prostate cancerProstate Cancer - Accurate application of Partin Tables in patients with prostate cancer assessedProstate Cancer - Adenovirus-mediated expression sensitizes prostate carcinoma cells to apoptosisProstate Cancer - Adoptive splenocyte transfer is therapeutic in a mouse prostate cancer modelProstate Cancer - Androgen receptor mutation implicated in prostate cancerProstate Cancer - Bone loss occurred after androgen deprivation therapy for prostate cancerProstate Cancer - Company realigns to focus on Provenge biologic license application for prostate cancer therapyProstate Cancer - Complete androgen ablation suppresses PSCA mRNA expression in prostate cancerProstate Cancer - Cystectomy in patients previously treated for prostate cancer linked to greater morbidityProstate Cancer - DRE deemed unnecessary in men with undetectable PSA after radical prostatectomyProstate Cancer - Docetaxel, estramustine and prednisone used to treat prostate cancerProstate Cancer - Phase III clinical development of Acapodene on course following planned safety reviewProstate Cancer - Prostate cancer awareness campaign extended to bass fishing with angler Rick ClunnProstate Cancer - Sentinel lymph node biopsy used to stage prostate cancerProstate Cancer - Study shows protein diagnostic marker PSP94 better at detecting prostate cancers than PSAProstate Cancer - Transition zone biopsies do not improve prostate cancer detectionProstate Cancer Vaccine - Docetaxel does not diminish effect of gonadotropin-releasing hormone vaccine in prostate cancerProteomics - Medical diagnostics lab announces availability of monoclonal cyclin EProteomics - Retinoblastoma tumor suppressor protein is down-regulated by HCV RNA polymerasePulmonary Lesions - Bronchoscopy and PET used to diagnose small pulmonary nodulesRadiation Therapy - Researchers' data advance radiation therapy researchRectal Cancer - Adverse effects of preoperative radiation therapy for rectal cancer examinedRectal Cancer - Tumor vascularity used to predict therapy outcome for low-lying rectal cancerRenal Cell Cancer - Genitofemoral nerve damage can occur during radiofrequency ablation of renal cell cancerRenal Cell Carcinoma - Manipulation of B7-H1 is a viable therapeutic option in patients with RCCRetroperitoneal Schwannoma - Surgical considerations during excision of retroperitoneal schwannoma listedRicin Vaccine - RiVax milestone achievedSarcomas - Role of new biological prognostic factors in soft tissue sarcomas reviewedSarcomas - Serum levels of CD44 could not be used to prognosticate pediatric sarcomasSarcomas - Vascular reconstruction deemed feasible in limb-salvage surgery for sarcomaStem Cell Research - ATR/Chk1 pathway inhibition induces a p38-dependent S-phase delay in ESCsStem Cell Research - Chemokines guide endothelial progenitors to new tumor vesselsStem Cell Transplantation - CD3/CD19-selected grafts advantageous for engraftment and immunoreconstitutionStem Cell Transplantation - Procedure developed to highly purify NK cells for immunotherapy after haploidentical SCTStem Cell Transplantation - Recent studies add new data to stem cell transplantation researchSurgical Technology - Angiographic catheter used for neuroendoscopic surgerySurgical Technology - Gamma knife surgery safe and effective after microsurgical resectionSurgical Technology - Studies describe new findings in surgical technology researchSurgical Technology - Ultrasonic dissector did not improve results of hepatic resectionThyroid Cancer - BRAF mutation linked to poorer clinical prognosis for papillary thyroid cancerThyroid Cancer - Vitamin D3 therapy used to treat locally advanced thyroid cancerTobacco Use - COX-2 and VEGFR-2 mediate nicotine-related angiogenesis and cancer invasionTobacco Use - Increased mortality associated with tobacco and smokeless tobacco useTransplant Medicine - Adenovirus specific T-cell reconstitution should be monitored after stem cell transplantationTransplant Medicine - Researchers report details of new studies and findings in the area of transplant medicineVaccine Adjuvant - Vesiculated alpha-tocopheryl succinate enhances effect of dendritic cell vaccinesVector Development - Researchers develop all-in-one gene delivery system to open new treatment avenuesWilms Tumor - Decrease in LRP expression linked to advanced stages of Wilms tumors
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