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Cancer Weekly

Susan Hasty, Publisher
Table of Contents . . . February 14th, 2006
Non-Subscriber - Summaries Only
Related Areas: Other Issues in Cancer Weekly | Other Publications

Bone Tumors - FDG-PET used to detect bone tumors when bone scintigraphy gave negative findings

Breast Cancer - New breast magnetic resonance imaging technique endorsed

Colon Cancer - Use of artepillin C helps prevent colon cancer

Drug Resistance - Chromosomal alterations resulted in drug resistance in cancer cells

Prostate Cancer - Antiprostasome antibody titer used as supplemental prostate cancer marker

Abdominal Tumors - Abdominal position shifts detected with radiation-planning CT scans

Adverse Drug Reaction - CYP17 polymorphism may influence tamoxifen-induced hepatic steatosis

Alcoholic Hepatitis - Glycine may prevent liver cancer by impeding angiogenesis

Amputation - Sarcoma identified as leading cause of limb amputation

Analgesia - Recommendations made on safety of cancer patient-controlled analgesia

Angiology - Only nonalcoholic fraction of red wine may protect DNA from oxidative damage

Antisense Technology - Antisense oligo DNA and small interfering RNA suppress malignant cancer cell phenotypes

Apoptosis - PDCD2_C domain might not be universally associated with apoptosis

Apoptosis - Transcription inhibition proposed as potential strategy for cancer therapeutics

Astrocytomas - Fractionated stereotactic reirradiation deemed effective in gliomas

Autoimmune Disease Research - NovImmune SA files IND in the Netherlands for a human antibody that targets the CD3 antigen

Awards - Komen Tulsa affiliate awards $340,000 to local organizations to aid breast cancer fight

Barrett Esophagus - Cryoablation used to eradicate Barrett esophagus

Barrett Esophagus - Progression to high-grade dysplasia in women with Barrett esophagus is similar to men

Bladder Cancer - New findings in the area of bladder cancer described

Bladder Cancer - Published study of protein-based bladder cancer test shows 99% of malignancies found

Bladder Cancer - Researcher reports NMP22 BladderChek Test detects three times more cases of bladder cancer

Bladder Cancer - Tobacco smoking and GSTP1 polymorphism linked to bladder carcinoma

Bladder Urothelial Cancer - COX-2 protein expression related to poor outcome of bladder urothelial carcinoma

Bone Marrow - Blimp-1 is required for formation and maintenance of long-lived plasma cells

Bone Metastases - (18)FDG-PET should complement bone scintigraphy for detecting bone metastases

Brain Cancer - 3 T deemed more beneficial than 1.5 T in brain tumor magnetic resonance imaging

Brain Cancer - Anti-angiogenic therapy in pediatric neuro-oncology discussed

Brain Cancer - Atypical teratoid/rhabdoid tumors of the central nervous system identified

Brain Cancer - Infections could contribute to adult brain tumors

Brain Cancer - No link shown between mobile phone use and increased risk of glioma tumors

Brain Cancer - Recent findings in brain cancer described

Brain Metastases - Role of chemotherapy in brain metastases examined

Brain Tumor - Restoring neurogenesis might treat cognitive sequelae of brain tumor therapy

Breast Cancer - Adiponectin expression induced apoptosis in MDA-MB-231 breast cancer cells

Breast Cancer - Adjuvant breast cancer therapy needs to move away from one-fits-all mentality

Breast Cancer - Androgen receptor activity reduces cancer risk in African-American women

Breast Cancer - Calcium signaling in cancer and vitamin D examined

Breast Cancer - Clinical trial tests delivery of chemotherapy directly to breast ducts

Breast Cancer - Combined gene therapy effect revealed in syngeneic murine breast cancer models

Breast Cancer - Declines in mortality from breast cancer represent progress in disease control

Breast Cancer - Dependable social relationships predicted survival in breast carcinoma patients

Breast Cancer - High-dose chemotherapy improved survival in breast cancer patients

Breast Cancer - Identification of all sentinel nodes may reduce risk of breast cancer recurrence

Breast Cancer - Mapping for sentinel lymph node biopsy is enhanced with combined diagnostic modalities

Breast Cancer - Multicenter phase II study of MKC-1 initiated in breast cancer

Breast Cancer - Positron emission tomography for breast cancer deemed cost-effective in Canada

Breast Cancer - Prognostic factors in breast cancer change over time

Breast Cancer - Recent studies add new data to breast cancer research

Breast Cancer - Reports add new data to breast cancer research

Breast Cancer - Researchers detail new studies and findings in the area of breast cancer

Breast Cancer - Role of autoimmunity in breast cancer has broad implications in therapy target discovery

Breast Cancer - Solid-state gamma camera used to depict sentinel lymph nodes in breast cancer

Breast Cancer - Spanish-preferring Latinas experienced delays in care for breast cancer

Breast Cancer - Spleen tyrosine kinase mediated breast tumor suppression

Breast Cancer - Study examines participation in online support groups for breast cancer patients

Breast Cancer - Survival after diagnosis of breast cancer varied in Switzerland

Breast Cancer - Ultrasonography detected infraclavicular lymph node metastases in breast cancer

Breast Cancer - Unsatisfactory coping and defending mechanisms linked to risk of breast cancer

Breast Cancer - Vaginal estrogen may pose risks to patients taking new breast cancer drugs

Breast Cancer Prevention - Physician education would enhance recruitment of Asian-American women into cancer research

Breast Cancer Prevention - Review examines therapeutic value of selective estrogen receptor modulators in breast cancer

Breast Cancer Risk Factors - Breast cancer risk for Hispanic women increases with length of residency in U.S.

Breast Cancer Risk Factors - Dietary calcium/dairy consumption have slight inverse association with breast cancer risk

Breast Cancer Risk Factors - Dietary factors may influence mammographic density and breast cancer risk

Breast Cancer Risk Factors - Some foods in traditional southern diet may reduce risk of invasive breast cancer

Breast Cancer Screening - Breast cancer survival is linked more to early diagnosis than to differential treatment

Breast Cancer Survival - Extended benefit for women after 5 years of tamoxifen therapy is observed with letrozole

Breast Cancer Survival - Regional differences in breast cancer survival are explained by low diagnostic activity

Breast Cancer Therapy - Report advocates use of epirubicin for adjuvant breast cancer chemotherapy

Breast Cancer Therapy - Risk of recurrence is reduced in women treated with letrozole for breast cancer

Breast Cancer Therapy - Studies add new findings to breast cancer therapy body of knowledge

Breast Cancer Vaccine - ST6GalNAc I expression in breast cancer cells enhances tumorigenicity

Breast Disease - Body fat at young age may reduce incidence of breast disease in premenopausal women

Business & Finance - License agreement for cancer therapy satraplatin to yield $40 million in milestone payments

Business Update - Circulating tumor cells are predictive of outcome for breast cancer patients

Cancer Cell Biology - icb-1 gene expression is inducible in breast and ovarian cancer cells

Cancer Diagnostics - Current imaging algorithm and new developments in cancer diagnostics reviewed

Cancer Diagnostics - Tumor markers and (18)FDG-PET could detect tumor recurrences

Cancer Drugs - Access to drugs for cancer varied across Canada

Cancer Drugs - Cytotoxicity of MDL 72527 demonstrated in cancer cells

Cancer Drugs - Recommended dose of irinotecan in pediatric cancer patients announced

Cancer Gene Therapy - Adeno-associated virus is tumoricidal because of inhibited angiogenesis

Cancer Gene Therapy - Capsid-modified adenovirus efficiently infects tumor endothelial cells

Cancer Gene Therapy - RNA interference enhances the cisplatin sensitivity of colorectal adenocarcinoma cells

Cancer Gene Therapy - Thymidylate synthase expression is inhibited by retrovirally introduced siRNA gene

Cancer Gene Therapy - Transfected, microencapsulated cells and ifosfamide treat peritoneal cancer

Cancer Genetics - Etheno-DNA adducts may be lead markers for inflammatory cancer-prone diseases

Cancer Immunology - Interleukin-1 receptor antagonist arrests the oncological effects of interleukin-1 beta

Cancer Immunotherapy - Antibody with human sugar structures can be produced in non-mammalian host

Cancer Incidence - Extra X chromosome does not appear to increase cancer incidence, mortality in women

Cancer Inhibition - Polymeric polyphenols inhibited hematologic tumor cell lines

Cancer Prevention - Lipid peroxidation was examined as possible chemoprotective mechanism for breast cancer

Cancer Prognostics - White blood cell count, inflammation predict cancer deaths

Cancer Research - Crystal structure holds clue to Aurora kinase inhibitor's efficacy against Gleevec-resistant kinase

Cancer Research - New development enables longer survival of cells, allowing opportunity for measurement

Cancer Research - Pennsylvania may opt to give tax refund to breast, cervical cancer research

Cancer Risk Factors - BRCA1 deficiency is linked to aberrant estrogen biosynthesis associated with cancer risk

Cancer Risk Factors - Cancer incidence and mortality in UK semiconductor workers examined

Cancer Risk Factors - Inconclusive BRCA1/2 testing results create anxiety in women about cancer risk

Cancer Survivors - Divide between cancer survivorship initiatives and minorities needs bridging

Cancer Survivors - Psychosocial problems faced by adult cancer survivors analyzed

Cancer Therapy - 2C4 disrupts HER kinase signaling pathway, inhibits ovarian carcinoma cell growth

Cancer Therapy - Antiproliferative and apoptosis-inducing activity of Brucea javanica shown

Cancer Therapy - By 2020 there will be 30M people living with cancer

Cancer Therapy - Calcitriol plus NSAIDs may be potential therapy for prostate cancer

Cancer Therapy - Cancer phenotypes are suppressed through a multifunctional actin-binding protein

Cancer Therapy - Cancer treatment system non-invasively focuses heat on drug-injected region

Cancer Therapy - High-risk profiles across cancer continuum defined via multidimensional approach

Cancer Therapy - Leptosins inhibit DNA topoisomerases and induce apoptosis

Cancer Therapy - Long-term side effects of adjuvant chemotherapy reviewed

Cancer Therapy - Meisoindigo curtails angiogenic processes in chronic myelogenous leukemia cells

Cancer Therapy - Mucosectomy is a sufficient therapy for early squamous cell of the esophagus

Cancer Therapy - New findings in the area of cancer therapy described

Cancer Therapy - New research in the area of cancer therapy detailed

Cancer Therapy - Oncolytic herpes simplex virus is useful in therapy of metastatic pleural cancer

Cancer Therapy - Oral cancer plasma tumor marker identified with proteomics technology

Cancer Therapy - Polysaccharide-rich substance with antitumor activity isolated from black currant juice

Cancer Therapy - Positive early responses reported on use of HepaSphere Microsphere for liver cancer

Cancer Therapy - Preclinical data demonstrating anticancer activity of Quadramet in multiple myeloma published

Cancer Therapy - Report presents useful techniques for evaluating cancer control efforts

Cancer Therapy - Researchers' work adds to cancer therapy body of knowledge

Cancer Therapy - Study explored zebularine metabolism by aldehyde oxidase in hepatic cytosol

Cancer Therapy - UHRF1 required in tumor cell proliferation

Cancer Vaccine - Dendritic cell therapy with IFN-alpha suppresses tumors in colorectal cancer

Cancer Vaccine - Gastric cancer cell-dendritic cell hybrids induce tumor-specific T cells

Cancer Vaccine - Melanoma patient has spontaneous CTL response to MAGE-A3 peptide

Cancer Vaccine - NKT lymphocytes confer immunity via tumor-capturing dendritic cells

Cancer Vaccine - Report summarizes European Conference on Progress in Vaccination Against Cancer

Cancer Vaccines - New data illuminates research in cancer vaccines

Cancer Vaccines - Researchers detail new studies and findings in the area of cancer vaccines

Carcinogenesis - Possibility examined of thiamin deficiency as major cause of some tumors

Cervical Cancer - HPV typing from paraffin-embedded sections of cervical cancers deemed feasible

Cervical Cancer - Increased GRP94 expression in cervical cancer cells is linked to decreased X-ray sensitivity

Cervical Cancer - Life sciences company inks MOU through U.S. State Department's Bio-Industry Initiative

Cervical Cancer - New data illuminates research in cervical cancer

Cervical Cancer Screening - Human papillomavirus-DNA testing may be useful to triage patients for colposcopy

Cervical Cancer Screening - Rate of cervical cancer among Zimbabwe women highlights value of screening programs

Cervical Cancer Vaccine - Study examined pediatricians' intention to administer HPV vaccine

Cervical Cancer Vaccine - Transcutaneous immunization protects against HPV-induced tumors

Cervical Lymph Node Metastasis - Tc-99m-MIBI SPECT and CT used in evaluation of cervical lymph node metastasis

Chemotherapy - Researchers describe findings in chemotherapy studies

Chronic Myelogenous Leukemia - Newly discovered Bcr-abl kinase inhibitor may have therapeutic potential in CML

Clinical Trials - Dosing begun in anticancer drug trial in patients with metastatic colorectal cancer

Clinical Trials - Phase 1 clinical trial of oral heat shock protein 90 inhibitor for cancer initiated

Clinical Trials - Positive new survival findings reported from phase II and III clinical trials of orBec

Collaborations - Anticancer drug discovery collaboration signed

Collaborations - Strategic alliance agreement establishes Molecular Center of Excellence

Colon Cancer - Colon cancer survival linked to regional lymph node metastasis

Colon Cancer - Estrogen receptor-beta gene in women is associated with increased colorectal cancer risk

Colon Cancer - Sphingosine kinase 1 levels rise in colon carcinomas

Colon Cancer - Use of adjuvant chemotherapy in colon cancer differs among race, gender, and age

Colorectal Cancer - Asian-Americans have low colorectal cancer screening rates

Colorectal Cancer - Clinicopathological features predicted microsatellite instability in colorectal carcinomas

Colorectal Cancer - Colorectal cancer in colonic Crohn disease linked to DNA-aneuploidy

Colorectal Cancer - Contrast-enhanced ultrasonography used during surgery for CRC liver metastases

Colorectal Cancer - Dietary fiber intake was not correlated with lower risk of colorectal cancer

Colorectal Cancer - Extracolonic findings during colorectal cancer screening were rarely of clinical significance

Colorectal Cancer - Use of germline DNA pharmacogenetics to study colorectal tumor DNA validated

Colorectal Cancer - Use of virtual CT colectomy suggested for laparoscopic colorectal surgery

Complementary & Alternative Medicine - Orbignya phalerata Mart activates peritoueal macrophages, which may assist in tumor treatment

Complementary & Alternative Medicine - Alternative medicine remedies might stimulate leukemic cell viability

Complementary & Alternative Medicine - Anti-inflammatory potential of Antrodia camphorata demonstrated

Complementary & Alternative Medicine - Blueberry flavonoids inhibited MMP activity in DU145 human prostate cancer cells

Complementary & Alternative Medicine - The plant compound hyperforin blocks angiogenesis

DNA Research - Positive data presented from test of alkylating anthraquinone on multiple cancer cell lines

DNA Research - Radiation sensitivity of fresh peripheral blood cells related to cancer status

Diagnostics - Angiogenic protein in nipple fluid detects breast cancer risk in women

Diagnostics - Chest CT has low sensitivity for distant metastases

Diagnostics - Clinical findings and cytology in disseminated TB can mimic anaplastic thyroid cancer

Diagnostics - Diagnostics company to supply test kits, including VScan, to China hospital in Anhui Province

Diagnostics - Extra-axillary sentinel node biopsy may help doctors manage early breast cancer

Diagnostics - Features of recurrent lung cancer cells may indicate depth of invasion in bronchial wall

Diagnostics - Interfacial properties of tissues may lead to biophysical marker of cervical cancer

Diagnostics - Intraoperative sentinel node detection enhances the staging of invasive bladder cancer

Diagnostics - Near-infrared spectroscopy is potential in vivo diagnostic of pancreatic cancer

Diagnostics - Novel approach facilitates tumor classification from gene expression profiles

Disease Associations - Acromegaly associated with increased risk of developing colonic tumors

Drug Development - Basal cell carcinoma phase I trial to be completed in first half of 2006

Drug Development - Multiple Myeloma Research Consortium selects preferred contract research organization

Drug Development - Patients with colorectal hepatic metastases may benefit from irinotecan-based adjuvant chemotherapy

Drug Development - Phase I study of EM-1421 underway targetting tumors unresponsive to conventional therapy

Drug Development - Reports describe recent advances in drug development research

Drug Development - Two antitumor agents can modify cell-bound DNA

Drug Development - Withdrawal of EMEA marketing application for rubitecan capsules announced

Drug Resistance - Transcription factors and drug resistance discussed

Ductal Carcinoma In Situ - Biological variables and prognosis of ductal carcinoma in situ discussed

Embryonal Cancer - Embryonic environment can 'normalize' tumor cells during postimplantation development

Endocrinology - Recent findings in endocrinology described

Endometrial Cancer - Estrogen exposure combined with inflammation may foster development of endometrial cancer

Endometrial Cancer - No chemoprotective effect for endometrial cancer was observed with regular aspirin use

Endometrial Cancer - Supplemental radiation therapy beneficial for stage I endometrial cancer

Enzymology - Cyclooxygenase-2 uses toll-like receptors to drive microbe-induced cancer invasion

Enzymology - Researchers publish new studies and findings in the area of enzymology

Esophageal Cancer - Appropriate staging system for esophageal carcinoma identified

Euosmia - Euosmia discovered as rare form of parosmia

Fanconi Anemia - Frog eggs help researchers understand Fanconi anemia

Finance - Cancer-focused biopharma company announces $21.6 million tax assisted financing

Finance - Genomics company reports losses of $0.10 per share

Finance - Immunotherapy company closes additional $1.2 million in investments

Finance - Immunotherapy developer announces proposed offering of common stock

Finance - NCI SPORE grant will fund basic and translational breast cancer research

Finance - Protein diagnostic products company closes $7 million financing

Finance - orBec maker secures $6 million equity commitment from Fusion Capital

Fitness & Wellness - Dietary changes and physical activity may improve the outcomes of breast cancer patients

Gastric B-Cell Lymphoma - Functional promotor polymorphism of TNF-alpha linked to gastric B-cell lymphoma

Gastric Cancer - Clinical characteristics and management of esophagogastric tumors discussed

Gastric Cancer - Elderly patients with gastric cancer treated by diathermic knife dissection

Gastric Cancer - Laparoscopically assisted distal gastrectomy with D2 lymph node dissection feasible

Gastric Cancer - Loss of ADAM23 function implicated in gastric carcinogenesis

Gastric Cancer - MGr1-antigen regulates multidrug resistance in gastric cancer cells

Gastroenterology - Inhibitor of DNA binding protein blockade halts gastric cancer metastasis

Gastroenterology - SP5 identified as a downstream gene of the beta-catenin/Tcf pathway

Gastrointestinal Stromal Tumor - STI571 was effective treatment for gastrointestinal stromal tumor

Gene Therapy - Transcriptional control of therapeutic genes targets proliferating tumor cells

Genetic Research - Role of tumor suppressor retinoblastoma protein Rb as a transcription regulator examined

Genetic Research - Tumor suppressor genetics reviewed

Genetics & Genomics - Differentially methylated promoters identified in tumor cell lines

Genetics & Genomics - Genes associated with telomerase activity identified in esophageal carcinoma cell lines

Genetics & Genomics - Genomic alterations noted in study may help explain mechanisms of lung cancer

Glioma - DTI used to individualize radiotherapy target volumes in glioma patients

Glioma - Radiotherapy is gaining ground as therapy option for childhood low grade glioma

Graft-versus-Host Disease - CD8+ SCs identified that generate and sustain allogeneic T-cell subsets in GVHD reactions

Gynecological Cancer - Nedaplatin exhibited strong antitumor activity in gynecological carcinomas

Head & Neck Cancer - Carboplatin and raltitrexed used to treat head and neck squamous cell carcinoma

Head & Neck Cancer - Cervicofacial and cervicothoracic rotation flaps used to reconstruct facial defects

Head & Neck Cancer - Chemoradiotherapy with taxotere and cisplatin used in head and neck cancer

Head & Neck Cancer - Head and neck cancer patients experienced delays in accessing clinical resources

Helicobacter Pylori - H. pylori-positive gastric mucosa is associated with lymphoid lymphoma

Hemangioendothelioma - Wide local excision recommended for epithelioid hemangioendothelioma

Hematology - Angiogenic factors may influence the outcomes of adults with acute lymphoblastic leukemia

Hepatitis C Virus - Hepatitis C virus E2 inhibits apoptosis

Hepatitis C Virus - Researchers' findings advance hepatitis C virus research

Hepatocellular Cancer - Human hepatocellular carcinoma-related biomarkers identified

Hepatocellular Cancer - Model described for nonalcoholic steatohepatitis and hepatocellular carcinoma

Hepatocellular Cancer - Protein kinase C alpha expression is regulated in human hepatocellular carcinoma

Hepatocellular Cancer - Reports describe recent advances in hepatocellular cancer research

Hepatocellular Cancer - Ser-mutated DNA can be quantitatively analyzed by mass spectrometry

Hepatocellular Cancer - Serum KL-6 serves as a tumor marker for hepatocellular carcinoma in HCV patients

Hereditary Cancer - Family System Illness model offered to patients and families coping with cancer

Hilar Cholangiocarcinoma - Resection recommended for idiopathic strictures with presumed malignancy

Hodgkin Disease - Creation of a breast health program for female survivors of Hodgkin disease advocated

Human Papillomavirus - Human papillomavirus in adolescents could lead to genital abnormalities

Human Papillomavirus - Study examined value of combined Pap and HPV testing in screening for cervical abnormalities

Imaging - Hypericin helps differentiate between glioblastoma and neurons in vitro

Imaging - Magnification endoscopy image analysis can aid diagnosis of gastric tumors

Imaging - Optical coherence tomography useful for imaging laryngeal microstructure

Imaging - Radiotherapy equipment supplied to London hospital

Imaging - Recent findings illuminate research in imaging

Interleukin-2 - Regulatory T cell depletion enhanced vaccine-mediated immunity in cancer patients

Kidney Cancer - Functional simulation of renal cancer in virtual reality environments designed

Laryngeal Cancer - Survival rate of patients with laryngeal cancer analyzed

Legal issues - Breach of contract lawsuit filed against Advanced Magnetics, Inc.

Leukemia - Allo-BMT reduced relapse risk of leukemia but did not improve survival

Leukemia - Changes in bone mineral density in survivors of childhood leukemia analyzed

Leukemia - Comparative genomic hybridization used to analyze Japanese B-CLL

Leukemia - Coping linked to survival in leukemia patients with bone marrow transplants

Leukemia - Dose intensification improves outcome of leukemia

Leukemia - Elderly patients with acute lymphoblastic leukemia treated with imatinib

Leukemia - Hairy cell leukemia developed in patient after cardiac transplantation

Leukemia - Importance of cytogenetics in diagnosis of leukemias assessed

Leukemia - Leukemia xenografts are inhibited by adenovirus-mediated tissue inhibitor

Leukemia - Move towards pathogenesis-oriented therapy of acute myeloid leukemia warranted

Leukemia - New findings in leukemia described

Leukemia - New findings in the area of leukemia detailed

Leukemia - Outcome in childhood acute myeloid leukemia found to be still unsatisfactory

Leukemia - Poor treatment outcomes in children with leukemia owed to low remission rate

Leukemia - Recent findings in leukemia described

Leukemia - Research in leukemia provides new insights

Leukemia - Researchers publish new studies and findings in the area of leukemia

Leukemia - TRAIL proposed as anticancer agent in acute myeloid leukemia

Leukemia - Treatment concepts of acute promyelocytic leukemia discussed

Leukemia - Verapamil analogues display multidrug reverting activity toward leukemia cells

Liver Cancer - Researchers provide details of new studies and findings in the area of liver cancer

Liver Disease - Oxidative cellular damage occurs often in non-alcoholic fatty liver diseases

Liver Function - Loss of function of liver retinoic acid leads to steatohepatitis and liver tumor

Lung Cancer - Data advance knowledge in lung cancer research

Lung Cancer - Endobronchial ultrasound-driven biopsy used to diagnose peripheral lung lesions

Lung Cancer - High-resolution CT used to classify shape of pulmonary nodules

Lung Cancer - Human lung cancer tumors are suppressed by a nuclear export mediator

Lung Cancer - Indian herbal medicine used to treat lung cancer

Lung Cancer - Iodide sensitizes non-small cell lung cancer cells to ionizing radiation

Lung Cancer - New imaging technology detects pulmonary nodules

Lung Cancer - Novel EGFR gene mutation could improve lung cancer patients' response to therapy

Lung Cancer - Palliative radiation actually a cure for some lung cancer patients

Lung Cancer - Radiation therapy and paclitaxel used to treat non-small cell lung cancer

Lung Cancer - Report issues failing grades for progress being made against lung cancer

Lung Cancer - Reports advance knowledge in lung cancer research

Lung Cancer - Research add new data to lung cancer body of knowledge

Lung Cancer - Topotecan/ifosfamide used to treat patients with platinum refractory lung cancer

Lung Cancer - Tumor diameter of non-small cell lung cancer correlated with long-term survival

Lymphoma - Neutrophils found to be activated in cutaneous T-cell lymphoma

Lymphoma - New hope of cure shed on primary splenic lymphoma

Malignant Glioma - Phase I recurrent malignant glioma trial 6-month follow-up complete, reovirus is well-tolerated

Market Analysis - More angiogenesis inhibitors expected to reach market in next 5 years, according to report

Medical Devices - NeoMatrix selects medical device developer to manufacture breast cancer screening system

Medical Devices - The RBE of the MIT epithermal neutron beam has been determined in a murine model

Medicare - Medicare contractor establishes reimbursement coverage policy for Oncotype DX breast cancer test

Medicare - Medicare shifted to an Average Sales Price-based reimbursement system

Medulloblastoma - Tumor suppressors collaborate with Patched to suppress medulloblastoma formation

Melanoma - Computer-aided diagnosis of melanocytic lesions proved useful

Melanoma - Invasive skin cancer a growing problem among Hispanics

Melanoma - Low-dose chemobiotherapy is effective in treatment of metastatic melanoma

Melanoma - Recent findings in melanoma provide new insights

Melanoma - Ultrasound used to map lymph node and subcutaneous metastases of melanoma

Mergers & Acquisitions - Biosil Limited and Nagor Limited schedule closing of medical products company acquisition

Multiple Myeloma - FDG-PET detected more lesions than MIBI scan in patients with multiple myeloma

Multiple Myeloma - Imexon combined with cytotoxic agents to improve therapeutic activity in myeloma

Myeloma - Use of imatinib in patients with refractory/relapsed myeloma had no effect

Nanotechnology - Nanoparticles can be used for the optical imaging of tumor E-selectin

Nasopharyngeal Cancer - Nasopharyngeal cancer treated by chemoradiotherapy and accelerated fractionation

Nasopharyngeal Cancer - Time for LMP-1 regression inversely related to nasopharyngeal cancer control

Nasopharyngeal Cancer - Wound treatment therapies in nasopharyngeal cancer patients compared

Neuroscience - Prion-protein 1 interaction promotes neuritogenesis and neuroprotection

Non-Hodgkin Lymphoma - TNF and lymphotoxin alfa polymorphisms related to poor outcome in non-Hodgkin lymphoma

Non-Hodgkin Lymphoma - Vaccine boosts survival in patients with aggressive non-Hodgkin lymphoma

Nuclear Medicine - Standards authority reports on safety of nuclear medicine procedures

Oligonucleotides - Splicing-sensitive microarrays detect and measure alternative splicing

Oncology - Exfoliation of fresh tumor tissue produces samples suitable for molecular profiling

Oncology - Recent findings in oncology provide new insights

Oncology - Researchers publish new studies and findings in the area of oncology

Oral Cancer Vaccine - DNA vaccine is effective against oral papillomavirus-linked oral cancer

Osteosarcoma - TNSALP, PHEX and MEPE induced by beta-glycerophosphate in osteosarcoma cells

Ovarian Cancer - Aggressive surgery benefited optimally debulked patients with ovarian cancer

Ovarian Cancer - NH2-terminally truncated p73 isoforms predicted poor prognosis in ovarian cancer

Ovarian Cancer - Ovarian tumor xenografts are imaged and treated using sodium iodide symporter-mediated radioiodide

Ovarian Cancer - Tumor protein D52 is overexpressed in ovarian cancer

Ovarian Cancer - Underlying mechanism connecting endometriosis and ovarian cancer needs defining

Ovarian Cancer Risk Factors - Endometriotic lesions are related to subsequent risk of ovarian cancers

Pancreatic Cancer - Congenital anomalies of spleen mimicked hematological disorders and solid tumors

Pancreatic Cancer - Pancreatic head resection performed with low mortality in specialized units

Pancreatic Cancer - Researchers' findings advance pancreatic cancer research

Pancreatic Cancer - Two cytologic patterns noted in invasive ductal adenocarcinoma of the pancreas

Patents - Pharma company receives patent covering Provecta in conjunction with ultrasound imaging

Patents - U.S. patent office grants allowance in biopharm company's second organic arsenic case

Personnel - AMD drug developer names John L. Armstrong, Jr. CEO

Personnel - Barbara Wallner, PhD, named senior VP for technical operations of cancer-focused company

Personnel - Biomedical funding company promotes Chad W. Souvignier to director

Personnel - Biopharma company builds drug-development team through new hires and promotion

Personnel - Biopharma company hires Mark W. Salyer as executive vice president of sales and marketing

Personnel - Biotech company signs investment banking agreement with Janney Montgomery Scott

Personnel - Kevin J. Buckman, MD, named to medical advisory board of medical diagnostics company

Personnel - Lloyd Sanders named vice president of sales and marketing for Genasense developer

Personnel - Meghan Fitzgerald joins cancer drug developer as chief business officer

Personnel - Pharma company announces the appointment of Anatole Klyosov as chief scientist

Personnel - Pharma company appoints Jeff Himawan to board of directors

Personnel - Stephen T.D. Dixon, CFO of cancer-focused company, resigns

Philanthropy - Cancer organization awards $105,000 in grants for cancer survivorship and outreach

Philanthropy - Financial services company extends commitment to underwrite children's health organization events

Philanthropy - Online grocery delivery company customers donate $12,000 to Hope Chest for Breast Cancer

Physiology - Microtubules have differential roles in megakaryocyte proplatelet formation

Pituitary Tumors - PRL secretion, tumor size and operation date predicted neurosurgical outcome in pituitary tumors

Product Licensing - Drug development company licenses formulation of opiate analgesic fentanyl for Japan

Prostate Cancer - A replicating adenovirus is useful for the treatment of prostate cancer

Prostate Cancer - Accurate application of Partin Tables in patients with prostate cancer assessed

Prostate Cancer - Adenovirus-mediated expression sensitizes prostate carcinoma cells to apoptosis

Prostate Cancer - Adoptive splenocyte transfer is therapeutic in a mouse prostate cancer model

Prostate Cancer - Androgen receptor mutation implicated in prostate cancer

Prostate Cancer - Bone loss occurred after androgen deprivation therapy for prostate cancer

Prostate Cancer - Company realigns to focus on Provenge biologic license application for prostate cancer therapy

Prostate Cancer - Complete androgen ablation suppresses PSCA mRNA expression in prostate cancer

Prostate Cancer - Cystectomy in patients previously treated for prostate cancer linked to greater morbidity

Prostate Cancer - DRE deemed unnecessary in men with undetectable PSA after radical prostatectomy

Prostate Cancer - Docetaxel, estramustine and prednisone used to treat prostate cancer

Prostate Cancer - Phase III clinical development of Acapodene on course following planned safety review

Prostate Cancer - Prostate cancer awareness campaign extended to bass fishing with angler Rick Clunn

Prostate Cancer - Sentinel lymph node biopsy used to stage prostate cancer

Prostate Cancer - Study shows protein diagnostic marker PSP94 better at detecting prostate cancers than PSA

Prostate Cancer - Transition zone biopsies do not improve prostate cancer detection

Prostate Cancer Vaccine - Docetaxel does not diminish effect of gonadotropin-releasing hormone vaccine in prostate cancer

Proteomics - Medical diagnostics lab announces availability of monoclonal cyclin E

Proteomics - Retinoblastoma tumor suppressor protein is down-regulated by HCV RNA polymerase

Pulmonary Lesions - Bronchoscopy and PET used to diagnose small pulmonary nodules

Radiation Therapy - Researchers' data advance radiation therapy research

Rectal Cancer - Adverse effects of preoperative radiation therapy for rectal cancer examined

Rectal Cancer - Tumor vascularity used to predict therapy outcome for low-lying rectal cancer

Renal Cell Cancer - Genitofemoral nerve damage can occur during radiofrequency ablation of renal cell cancer

Renal Cell Carcinoma - Manipulation of B7-H1 is a viable therapeutic option in patients with RCC

Retroperitoneal Schwannoma - Surgical considerations during excision of retroperitoneal schwannoma listed

Ricin Vaccine - RiVax milestone achieved

Sarcomas - Role of new biological prognostic factors in soft tissue sarcomas reviewed

Sarcomas - Serum levels of CD44 could not be used to prognosticate pediatric sarcomas

Sarcomas - Vascular reconstruction deemed feasible in limb-salvage surgery for sarcoma

Stem Cell Research - ATR/Chk1 pathway inhibition induces a p38-dependent S-phase delay in ESCs

Stem Cell Research - Chemokines guide endothelial progenitors to new tumor vessels

Stem Cell Transplantation - CD3/CD19-selected grafts advantageous for engraftment and immunoreconstitution

Stem Cell Transplantation - Procedure developed to highly purify NK cells for immunotherapy after haploidentical SCT

Stem Cell Transplantation - Recent studies add new data to stem cell transplantation research

Surgical Technology - Angiographic catheter used for neuroendoscopic surgery

Surgical Technology - Gamma knife surgery safe and effective after microsurgical resection

Surgical Technology - Studies describe new findings in surgical technology research

Surgical Technology - Ultrasonic dissector did not improve results of hepatic resection

Thyroid Cancer - BRAF mutation linked to poorer clinical prognosis for papillary thyroid cancer

Thyroid Cancer - Vitamin D3 therapy used to treat locally advanced thyroid cancer

Tobacco Use - COX-2 and VEGFR-2 mediate nicotine-related angiogenesis and cancer invasion

Tobacco Use - Increased mortality associated with tobacco and smokeless tobacco use

Transplant Medicine - Adenovirus specific T-cell reconstitution should be monitored after stem cell transplantation

Transplant Medicine - Researchers report details of new studies and findings in the area of transplant medicine

Vaccine Adjuvant - Vesiculated alpha-tocopheryl succinate enhances effect of dendritic cell vaccines

Vector Development - Researchers develop all-in-one gene delivery system to open new treatment avenues

Wilms Tumor - Decrease in LRP expression linked to advanced stages of Wilms tumors

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