Cancer Vaccine

Dendritic cell therapy with IFN-alpha suppresses tumors in colorectal cancer

Published in Cancer Weekly, February 14th, 2006

Dendritic cell therapy with interferon-alpha synergistically suppresses outgrowth of established tumors in a murine colorectal cancer model.

Scientists writing in the journal Gene Therapy report, "Both dendritic cell (DC)-based immunotherapy and interferon (IFN)-alpha therapy have been proved to have potent long-lasting antitumor effects. In anticipation of synergistic antitumor effects, we performed combination therapy with DCs and IFN-alpha gene transduced murine colorectal cancer MC38 cells (MC38-IFN-alpha)."

"DCs incubated with MC38-IFN-alpha, but not neomycin-resistance gene-transduced MC38 cells (MC38-Neo), effectively enhanced...

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Source: Cancer Weekly (2006-02-14)

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