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Apoptosis
PDCD2_C domain might not be universally associated with apoptosis
February 14th, 2006
Scientists suggested the PDCD2_C domain might not be universally associated with apoptosis. According to a study from the People's Republic of China, "There are only two isoforms of PDCD2 and MGC13096 containing PDCD2_C domain in human genome. To study the role of PDCD2_C domain in apoptosis, the cDNAs of two isoforms of PDCD2 and MGC13096 were cloned." "The RT-PCR products (AY948416, AY948417) of PDCD2 from RNA of human embryonic kidney 293T (HEK293T) and gastric cancer AGS cell line lost common 99 bp when compared with the sequences of NCBI database (NM_002598, NM_144781). The data of expression of PDCD2 and MGC13096 genes in HEK293T cells which...
Source: Cancer Weekly (2006-02-14)
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